Patents by Inventor Amit Parekh

Amit Parekh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • IN VITRO BILIARY EXCRETION ASSAY
    Publication number: 20200141926
    Abstract: An in vitro methods of characterizing biliary excretion of a chemical entity using a single hepatocyte culture. Comprising providing cell culture comprising hepatocytes forming at least one bile canaliculus; contacting the cell culture with a first chemical entity for a time sufficient to allow uptake of the chemical entity by hepatocytes in the culture; disrupting the at least one bile canaliculus without lysing the hepatocytes and detecting the amount (if any) of the first chemical entity and/or a metabolite thereof released by the at least one bile canaliculus; and lysing the hepatocytes and detecting the amount of the first chemical entity and/or a metabolite thereof released by the hepatocytes.
    Type: Application
    Filed: December 22, 2019
    Publication date: May 7, 2020
    Inventors: Eric NOVIK, Cheul CHO, Amit PAREKH, Robert FREEDMAN, Martin L. YARMUSH, Eric PLUDWINSKI
  • PRIMARY MAMMALIAN CELL CULTURE SYSTEMS AND METHODS
    Publication number: 20170260490
    Abstract: Primary mammalian cell culture systems, methods of making primary mammalian cell culture systems, and methods of culturing primary mammalian cells are provided. In some embodiments the systems and methods utilize an exothermic chemical process as a heat source for culturing and shipping cultures comprising primary mammalian cells.
    Type: Application
    Filed: August 19, 2015
    Publication date: September 14, 2017
    Applicant: HUREL CORPORATION
    Inventors: Erik NOVIK, Amit PAREKH, Eric PLUDWINSKI, Anil SHRIRAO
  • IN VITRO BILIARY EXCRETION ASSAY
    Publication number: 20160061820
    Abstract: An in vitro methods of characterizing biliary excretion of a chemical entity using a single hepatocyte culture. Comprising providing cell culture comprising hepatocytes forming at least one bile canaliculus; contacting the cell culture with a first chemical entity for a time sufficient to allow uptake of the chemical entity by hepatocytes in the culture; disrupting the at least one bile canaliculus without lysing the hepatocytes and detecting the amount (if any) of the first chemical entity and/or a metabolite thereof released by the at least one bile canaliculus; and lysing the hepatocytes and detecting the amount of the first chemical entity and/or a metabolite thereof released by the hepatocytes.
    Type: Application
    Filed: September 2, 2015
    Publication date: March 3, 2016
    Inventors: Eric NOVIK, Cheul CHO, Amit PAREKH, Robert FREEDMAN, Martin L. YARMUSH
  • PROCESS FOR IMPROVING AROMATICITY OF HEAVY AROMATIC HYDROCARBONS
    Publication number: 20130313159
    Abstract: A process for producing paraffin extracted clarified slurry oil (raffinate) with improved aromaticity from the feed stock such as clarified slurry oil (CSO) is provided. The obtained paraffin extracted clarified slurry oil with improved aromaticity is suitable for a variety of industrial applications. For example, it can be used as a valuable feedstock for producing carbon black.
    Type: Application
    Filed: February 10, 2012
    Publication date: November 28, 2013
    Applicant: RELIANCE INDUSTRIES LIMITED
    Inventors: Mahesh Marve, Suyog Salgarkar, Manthan Malvankar, Amit Parekh, Vinod Rayan, Ashwani Yadav, Harender Bisht, Manoj Yadav, Sukumar Mandal, Asit Das