Abstract: The disclosure provides polypeptides and encoding nucleic acids of engineered formate dehydrogenases. The disclosure also provides cells expressing an engineered formate dehydrogenase. The disclosure further provides methods for producing a bioderived compound comprising culturing cells expressing an engineered formate dehydrogenase. Where the engineered formate dehydrogenase is capable of catalyzing a conversion.

Abstract: The disclosure provides pharmaceutical compositions comprising an anti-PD-1 antibody or an anti-PD-L1 antibody. In some aspects, the pharmaceutical compositions are formulated for subcutaneous delivery. In some aspects, the pharmaceutical compositions further comprise an endoglycosidase hydrolase enzyme. Other aspects of the present disclosure are directed to methods of subcutaneously delivering a pharmaceutical composition comprising an anti-PD-1 antibody or an anti-PD-L1 antibody.

Abstract: Systems, methods, and devices that relate to adaptive selection of communication infrastructure are disclosed. In one example aspect, a method for wireless communication includes performing or receiving measurements of a serving cell and one or more neighboring cells based on a configuration from a base station. The method also includes comparing a first measurement result associated with a first channel condition of the serving cell and a second measurement result associated with a second channel condition of the one or more neighboring cells and adjusting an interval of time between two searches for an access network according to the comparing of the first measurement result and the second measurement result.

Abstract: Systems, methods, and devices that relate to adaptive selection of communication infrastructure are disclosed. In one example aspect, a method for wireless communication includes performing or receiving measurements of a serving cell and one or more neighboring cells based on a configuration from a base station. The method also includes comparing a first measurement result associated with a first channel condition of the serving cell and a second measurement result associated with a second channel condition of the one or more neighboring cells and adjusting an interval of time between two searches for an access network according to the comparing of the first measurement result and the second measurement result.

Abstract: The disclosure provides pharmaceutical compositions comprising an anti-PD-1 antibody or an anti-PD-L1 antibody. In some aspects, the pharmaceutical compositions are formulated for subcutaneous delivery. In some aspects, the pharmaceutical compositions further comprise an endoglycosidase hydrolase enzyme. Other aspects of the present disclosure are directed to methods of subcutaneously delivering a pharmaceutical composition comprising an anti-PD-1 antibody or an anti-PD-L1 antibody.

Abstract: The Collaborative Non-Fungible Token Advertising System (100) for Targeted Influence on Social Network introduces a novel approach where brands collaborate with influencers (102) to co-create NFTs featuring brand-related contents (103). The NFTs are strategically displayed to influencer networks (104), leveraging credibility and engagement for effective advertising. Through secure blockchain technology (107) and interactive interfaces, the system (100) optimizes revenue generation (105) and revenue sharing (106), user interaction, and authenticity, thereby revolutionizing advertising dynamics within social networks.

Abstract: The present invention discloses a system (100) for direct content monetization through a Non-Fungible Token (NFT) on a social networking platform (101). Users are provided with a Content Creation Module (102) that empowers them to generate diverse digital content. A Conversion Module (103) transforms user-generated content into valuable NFTs. A Display Module (104) seamlessly integrates NFTs into the platform's interface, enhancing content visibility. An Economic Transaction Module (105) enables various economic transactions involving NFTs. A Payment Processing Module (106) offers flexible payment options, including cryptocurrencies and fiat currency. The system harnesses blockchain technology (107) to ensure transparent and secure recording of NFT ownership and transactions. Together, these components redefine content monetization, bridging the gap between creators and their audiences, and creating a unified platform for content creators to realize the full potential of their creations.

Abstract: The present invention discloses an integrated anti-trolling and content moderation system (100) for an online platform that pioneers a transformative approach to a digital interaction. Through a Troll Detection Module (102), offensive content is thwarted at its source, while a Personalized Moderation Module (103) empowers the user to nominate moderators for pre-publication assessment, fostering transparency and accountability. Augmenting user communication, an AI-driven Suggestions Module (104) provides the user with alternative rephrasing suggestions before posting, fostering the promotion of polite and constructive communication. The system incorporates a Collaborative Moderation Module (105), enabling the collective assessment of a content by multiple moderators. A user profile management Module (106) diligently tracks and showcases true positive trolling instances, accompanied by temporary commenting restrictions following the identification of trolling behavior.

Abstract: The present invention discloses an integrated system (100) within the online social networking platforms (101), designed to ensure authenticity and amplify user engagement. The system (100) orchestrates the enabling of users to upload both avatar and real images, linked to their profiles, thus giving rise to bona fide visual identities. Facilitated by a user-friendly interface (103), the system (100) provides effortless transitions between avatar and real profile images, thereby enriching engagement encounters. The assurance of controlled access to authentic image profiles is administered through a permission management module (105). Moreover, the system employs placeholder notifications to gently guide users in aligning their visual identities, thus fostering an environment that embodies authenticity, security, and heightened engagement within the online social networking realm.

Abstract: The disclosed invention relates to a commenting entitlement system (100) within an online social networking platform (101), leveraging real-ID verification for enhanced user interactions. The system (100) comprises a real ID setup module (102) that streamlines real-ID verification during user registration, fortifying identity authenticity. Furthermore, the system (100) incorporates a commenting module (103) permitting users with verified real IDs to engage in diverse interaction activities on the online social networking platform (101). Additionally, a user ‘hash’ generation module (104) is integrated, producing a distinct user ‘hash’ that anonymously correlates real IDs with corresponding user profiles, ensuring confidential connections and a multi-account prevention module (105) is integrated, constraining engagement across multiple accounts using identical real ID-based user ‘hashes.

Abstract: A system (100) for evaluating user demeanor and authenticity comprises a profile ring feature module (102) configured to exhibit a profile ring on a profile of each user, wherein the profile ring serves as an indicator within an online social networking platform (101), a user activity tracking module (103) configured to generate one or more signals derived from a plurality of actions executed by users on the online social networking platform (101), a notification module (104) configured to provide real time notifications to the user upon detecting variations in the color of the profile ring, Further, the present invention discloses a method (200) that generates valuable data about user engagement patterns and behavior. This data is analyzed over time to derive insights into user trends, preferences, and interactions, aiding in platform improvement and strategic decision-making.

Abstract: The disclosure provides pharmaceutical compositions comprising an anti-PD-1 antibody or an anti-PD-L1 antibody. In some aspects, the pharmaceutical compositions are formulated for subcutaneous delivery. In some aspects, the pharmaceutical compositions further comprise an endoglycosidase hydrolase enzyme. Other aspects of the present disclosure are directed to methods of subcutaneously delivering a pharmaceutical composition comprising an anti-PD-1 antibody or an anti-PD-L1 antibody.

Abstract: The disclosure provides pharmaceutical compositions comprising an antibody and at least two antioxidants. In some aspects, pharmaceutical composition is formulated for subcutaneous delivery. In some aspects, the pharmaceutical composition further comprises an endoglycosidase hydrolase enzyme. Other aspects of the present disclosure are directed to methods of subcutaneously delivering the pharmaceutical composition.

Abstract: A formation method is provided. During this formation method, a metallic substrate is provided. A coating is deposited onto the metallic substrate using a suspension plasma spray process. The coating is formed from or otherwise includes copper oxide.

Abstract: Disclosed is an approach to implement an architecture and methodology that allows rapid access to provisioned software without requiring the entirety of the software distribution to be transferred to the target system in an upfront manner. Instead, a multi-tier architecture is used that allows the software to be provisioned and accessed with efficient access and reads of distribution materials from one or more remote storage locations.

Abstract: Disclosed is an approach to implement an architecture and methodology that allows rapid access to provisioned software without requiring the entirety of the software distribution to be transferred to the target system in an upfront manner. Instead, a multi-tier architecture is used that allows the software to be provisioned and accessed with efficient access and reads of distribution materials from one or more remote storage locations.

Abstract: The disclosure provides pharmaceutical compositions comprising an antibody and at least two antioxidants. In some aspects, pharmaceutical composition is formulated for subcutaneous delivery. In some aspects, the pharmaceutical composition further comprises an endoglycosidase hydrolase enzyme. Other aspects of the present disclosure are directed to methods of subcutaneously delivering the pharmaceutical composition.

Abstract: The disclosure provides pharmaceutical compositions comprising an anti-PD-1 antibody or an anti-PD-L1 antibody. In some aspects, the pharmaceutical compositions are formulated for subcutaneous delivery. In some aspects, the pharmaceutical compositions further comprise an endoglycosidase hydrolase enzyme. Other aspects of the present disclosure are directed to methods of subcutaneously delivering a pharmaceutical composition comprising an anti-PD-1 antibody or an anti-PD-L1 antibody.

Abstract: Techniques are provided for transitioning from a hierarchical file system to an object store. A request is received to change file metadata of a hierarchical file system. In response to the request: in-cache file metadata of the hierarchical file system is modified. The in-cache file metadata includes a directory structure of the hierarchical file system and file metadata of the hierarchical file system. Additionally, an in-store metadata journal entry is generated. The in-store metadata journal entry indicates an update to in-store file metadata. The in-store file metadata includes the directory structure of the hierarchical file system and file metadata of the hierarchical file system and is stored in an object store. The in-store metadata journal entry is stored in the object store. Furthermore, in-store file metadata and in-store metadata journal entry may be used to reconstruct the in-cache file metadata on another node.

Abstract: Systems and methods are described for providing subtitles based on a user's language proficiency. An illustrative method includes receiving a request to display subtitles, selecting a language for the subtitles, determining, from a user profile, a user's proficiency level in the selected language, selecting, based on the user's proficiency level in the selected language, a set of subtitles from a plurality of sets of subtitles in the selected language, wherein each respective set of subtitles corresponds to a different proficiency level in the selected language, and generating for display the selected set of subtitles.