Patents by Inventor Amita M. Chaudhari

Amita M. Chaudhari has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Triazolones as fatty acid synthase inhibitors
    Patent number: 9340529
    Abstract: This invention relates to the use of triazolone derivatives for the modulation, notably the inhibition of the activity or function of fatty acid synthase (FAS). Suitably, the present invention relates to the use of triazolones in the treatment of cancer.
    Type: Grant
    Filed: November 4, 2013
    Date of Patent: May 17, 2016
    Assignee: GlaxoSmithKline LLC
    Inventors: Nicholas David Adams, Christopher Joseph Aquino, Amita M. Chaudhari, Jonathan Michael Ghergurovich, Terence John Kiesow, Cynthia Ann Parrish, Alexander Joseph Reif, Kenneth Wiggall
  • Triazolones as fatty acid synthase inhibitors
    Patent number: 8802864
    Abstract: This invention relates to the use of triazolone derivatives of Formula (I) for the modulation, notably the inhibition of the activity or function of fatty acid synthase (FAS). Suitably, the present invention relates to the use of triazolones in the treatment of cancer.
    Type: Grant
    Filed: February 22, 2011
    Date of Patent: August 12, 2014
    Assignee: GlaxoSmithKline LLC
    Inventors: Nicholas D. Adams, Christopher Joseph Aquino, Amita M. Chaudhari, Jonathan M. Ghergurovich, Terence John Kiesow, Cynthia A. Parrish, Alexander Joseph Reif, Kenneth Wiggall
  • TRIAZOLONES AS FATTY ACID SYNTHASE INHIBITORS
    Publication number: 20140100213
    Abstract: This invention relates to the use of triazolone derivatives for the modulation, notably the inhibition of the activity or function of fatty acid synthase (FAS). Suitably, the present invention relates to the use of triazolones in the treatment of cancer.
    Type: Application
    Filed: November 4, 2013
    Publication date: April 10, 2014
    Applicant: GlaxoSmithKline LLC
    Inventors: Nicholas David Adams, Christopher Joseph Aquino, Amita M. Chaudhari, Jonathan Michael Chergurovich, Terence John Kiesow, Cynthia Ann Parrish, Alexander Joseph Reif, Kenneth Wiggall
  • FATTY ACID SYNTHASE INHIBITORS
    Publication number: 20130237535
    Abstract: This invention relates to the use of spirocyclic piperidine derivatives for the modulation, notably the inhibition of the activity or function of fatty acid synthase (FAS). Suitably, the present invention relates to the use of spirocyclic piperidines in the treatment of cancer.
    Type: Application
    Filed: November 7, 2011
    Publication date: September 12, 2013
    Inventors: Nicholas D. Adams, Amita M. Chaudhari, Terence John Kiesow, Cynthia Ann Parrish, Alexander Joseph Reif, Lance Howard Ridgers, Stanley J. Schmidt, Kenneth Wiggall
  • TRIAZOLONES AS FATTY ACID SYNTHASE INHIBITORS
    Publication number: 20120316151
    Abstract: This invention relates to the use of triazolone derivatives of Formula (I) for the modulation, notably the inhibition of the activity or function of fatty acid synthase (FAS). Suitably, the present invention relates to the use of triazolones in the treatment of cancer.
    Type: Application
    Filed: February 22, 2011
    Publication date: December 13, 2012
    Inventors: Nicholas D. Adams, Christopher Joseph Aquino, Amita M. Chaudhari, Jonathan M. Ghergurovich, Terence John Kiesow, Cynthia A. Parrish, Alexander Joseph Reif, Kenneth Wiggall
  • AZABENZIMIDAZOLES AS FATTY ACID SYNTHASE INHIBITORS
    Publication number: 20120295915
    Abstract: Disclosed are compounds having Formula (I), wherein R1, R2, R3, R4, Ra, Rb, X, Y, m, and n are defined herein and methods of using the same.
    Type: Application
    Filed: November 22, 2010
    Publication date: November 22, 2012
    Inventors: Amita M. Chaudhari, Jason Hallman, Christopher P. Laudeman, David Lee Musso, Cynthia A. Parrish
  • NAPHTHYRIDINE, DERIVATIVES AS P13 KINASE INHIBITORS
    Publication number: 20100179143
    Abstract: Invented is a method of inhibiting the activity/function of PI3 kinases using naphthyridine derivatives. Also invented is a method of treating one or more disease states selected from: autoimmune disorders, inflammatory diseases, cardiovascular diseases, neurodegenerative diseases, allergy, asthma, pancreatitis, multiorgan failure, kidney diseases, platelet aggregation, cancer, sperm motility, transplantation rejection, graft rejection and lung injuries by the administration of naphthyridine derivatives.
    Type: Application
    Filed: May 29, 2008
    Publication date: July 15, 2010
    Inventors: Nicholas D. Adams, Joelle L. Burgess, Amita M. Chaudhari, David Knight, Cynthia A. Parrish
  • QUINOLINE DERIVATIVES AS P13 KINASE INHIBITORS
    Publication number: 20100168100
    Abstract: Invented is a method of inhibiting the activity/function of PI3 kinases using quinoline derivatives. Also invented is a method of treating one or more disease states selected from: autoimmune disorders, inflammatory diseases, cardiovascular diseases, neurodegenerative diseases, allergy, asthma, pancreatitis, multiorgan failure, kidney diseases, platelet aggregation, cancer, sperm motility, transplantation rejection, graft rejection and lung injuries by the administration of quinoline derivatives.
    Type: Application
    Filed: May 16, 2008
    Publication date: July 1, 2010
    Applicant: SMITHKLINE BEECHAM CORPORATION
    Inventors: Nicholas D. Adams, Amita M. Chaudhari
  • Azaindole inhibitors of aurora kinases
    Patent number: 7495102
    Abstract: The present invention relates to a compound represented by Formula (I): and pharmaceutically acceptable salts. Compounds of the present invention inhibit Aurora kinase, making them especially suitable for the treatment of a number of diseases, including solid tumor cancers and hematological cancers.
    Type: Grant
    Filed: September 14, 2007
    Date of Patent: February 24, 2009
    Assignee: SmithKline Beecham Corporation
    Inventors: Martha A. Sarpong, Nicholas D. Adams, Jeffrey Michael Axten, Amita M. Chaudhari, Dashyant Dhanak, Toshihiro Hamajima, Kenneth Allen Newlander, Cynthia A. Parrish, Jerry Leroy Adams, Domingos J. Silva, Jun Tang