Abstract: The invention relates to new use of hydroxystearic acid for inducing secretion of anti-microbial peptides (AMPs) when applied on an external surface of the human body. It also relates to an antimicrobial composition comprising a combination of hydroxystearic acid and antimicrobial peptides or antimicrobial lipids or mixtures thereof. This has application in improving the immunity of skin, scalp and oral cavity against attack by microorganisms.

Abstract: The invention relates to a topical sanitising composition comprising: a) polyhydroxy compound selected from a saccharide, a polyol, or combinations thereof; b) antimicrobial lipid; and c) tetrahydroxypropyl ethylenediamine (THPE), wherein the antimicrobial lipid and THPE are present in a weight ratio from 1:10,000 to 1:10. The invention further relates to a method of disinfecting a surface by applying the aforementioned topical composition onto said surface and to the use of the same composition for sanitising skin, hair or the oral cavity. The invention also relates to use of a polyhydroxy compound selected from a saccharide, a polyol or combinations thereof, as an antimicrobial activity promoter.

Abstract: The present invention relates to a topical composition comprising from 0.001 to 10% by weight a compound of formula (I), i.e. N-cyclopropyl nicotinamide, that provides improved antimicrobial effect through generation of antimicrobial peptides when applied to an external surface of the human body. A combination of compound of formula I and at least one ingredient selected from niacinamide, picolinamide and iso-nicotinamide triggers generation of AMPs in a synergistic way.

Abstract: This invention relates to a water in oil emulsion composition which provides enhanced delivery of water soluble skin benefit agent. The invention more particularly relates to a wash off composition e.g that for washing hair, body, hand or face which generally contain anionic surfactants and yet provide enhanced delivery of such agents. It does this by delivering the actives through a specific water-in-oil emulsion. The water-in-oil emulsion comprises a hydrophobic phase preferably petrolatum with preferred emulsifiers being non-ionic surfactant of specified HLB range.

Abstract: The present invention relates to an extruded soap bar composition. It more particularly relates to a soap bar composition which delivers the enhanced antimicrobial benefit to skin while ensuring that the soap bar is easy to extrude. This is achieved by including free fatty acids in the soap bar composition while ensuring that part of the free fatty acid is hydroxy stearic acid.

Abstract: The present invention relates to a topical composition and more particularly a topical composition for antimicrobial benefit. According to the present invention there is provided a topical composition comprising Niacinamide and picolinamide wherein the molar ratio of Niacinamide to picolinamide is from I:20 to 20:I.

Abstract: The present invention relates to an antimicrobial composition. More particularly the present invention relates to an antimicrobial composition for malodor and oral biofilm inhibitions benefits. Accordingly, the present invention provides an antimicrobial composition comprising: a. 0.1 to 10% by weight of tetrahydroxypropyl ethylenediamine (THPE) and, b. 0.001 to 10% by weight of at least one compound selected from a biphenol.

Abstract: The present invention relates to a topical composition. The present invention more particularly relates to a topical composition for antimicrobial benefit and a method of disinfecting a surface. According to the invention there is provided a topical composition comprising: a) 0.1 to 10% by weight of Niacinamide or its derivatives; b) 0.01% to 5% by weight of a first quaternary ammonium salt comprising Didecyl Dimethyl Ammonium Chloride; c) 0.01 to 5% by weight of a second quaternary ammonium salt; and d) a cosmetically acceptable base.

Abstract: This invention relates to an antimicrobial composition, more particularly a personal care composition like a soap bar. It more particularly relates to a composition comprising an essential oil compound and a tetra hydroxy alkylene amine compound which interact synergistically to provide the desired result.

Abstract: The present invention relates to an extruded soap bar composition. It more particularly relates to a soap bar composition which delivers the enhanced antimicrobial benefit to skin while ensuring that the soap bar is easy to extrude. This is achieved by including free fatty acids in the soap bar composition while ensuring that part of the free fatty acid is hydroxy stearic acid.

Abstract: The invention relates to a sanitizer composition for topical use, i.e. for application onto the human skin, especially on hands for instantaneous disinfection of the body part while imparting long lasting immunity benefit. The sanitizer composition comprising high amount of alcohol and vitamin B3 compound or a derivative thereof is seen to be hazy and this problem is solved by inclusion of specific type non-ionic surfactant.

Abstract: This invention relates to an antimicrobial composition for application onto human skin, said composition comprising: a. 20 to 90 wt. % of one or more C2 to C4 monohydric alcohols; b. 0.5 to 10 wt. % vitamin B3 compound; c. 1 to 20 wt. % of one or more polyols; and wherein the weight ratio of the vitamin B3 compound to the one or more polyols is in the range of 1:2 to 1:20 and wherein the viscosity of the composition is in the range of 0.5 Pa s (500 cps) to 18 Pa s (18000 cps) at 25° C. wherein the one or more C2 to C4 monohydric alcohols are selected from ethanol, isopropyl alcohol and combinations thereof and further wherein the composition comprises a combination of ethanol and isopropyl alcohol.

Abstract: The present invention relates to a topical composition comprising a compound pf formula (I) wherein R is a cycloalkyl group with the total number of carbon atoms in the cycloalkyl group in the range 4 to 6.

Abstract: The present invention relates to a topical composition comprising from 0.001 to 10% by weight a compound of formula (I), i.e. N-cyclopropyl nicotinamide, that provides improved antimicrobial effect through generation of antimicrobial peptides when applied to an external surface of the human body. A combination of compound of formula I and at least one ingredient selected from niacinamide, picolinamide and iso-nicotinamide triggers generation of AMPs in a synergistic way.

Abstract: The present invention relates to a topical composition and more particularly a topical composition for antimicrobial benefit. According to the present invention there is provided a topical composition comprising Niacinamide and picolinamide wherein the molar ratio of Niacinamide to picolinamide is from I:20 to 20:I.

Abstract: The present invention relates to a topical composition and more particularly a topical composition for antimicrobial benefit. According to the present invention there is provided a topical composition comprising Niacinamide and picolinamide wherein the molar ratio of Niacinamide to picolinamide is from 1:20 to 20:1.

Abstract: The invention relates to a personal care composition which provides enhanced inter-cellular tight junction in skin cells. The invention more particularly relates to use of such composition for application on skin, scalp, hair and oral cavity. The personal care composition comprises an extract of Aloe vera and a hyaluronic acid polymer having a molecular weight from 5 to 60 kDa.

Abstract: The present invention provides an antimicrobial composition comprising a) Thymol; b) Terpineol; c) Niacinamide or its derivatives thereof; and d) a cosmetically acceptable base.

Abstract: The invention relates to a specific fraction of Aloe vera extract for enhancing tight junction in skin cells. The invention more particularly relates to use of such a fraction in skin, oral and hair care compositions. The inventive extract of Aloe vera comprises 60 to 95% by weight of polysaccharides having a molecular weight in the range of 2 to 3 kDa, and less than 5% polyphenols, wherein the polysaccharides are hydrolysed by trifiuoroacetic acid.

Abstract: This invention relates to an antimicrobial composition for application onto human skin, said composition comprising: a. 20 to 90 wt. % of one or more C2 to C4 monohydric alcohols; b. 0.5 to 10 wt. % vitamin B3 compound; c. 1 to 20 wt. % of one or more polyols; and wherein the weight ratio of the vitamin B3 compound to the one or more polyols is in the range of 1:2 to 1:20 and wherein the viscosity of the composition is in the range of 0.5 Pa s (500 cps) to 18 Pa s (18000 cps) at 25° C. wherein the one or more C2 to C4 monohydric alcohols are selected from ethanol, isopropyl alcohol and combinations thereof and further wherein the composition comprises a combination of ethanol and isopropyl alcohol.