Patents by Inventor Amjad Askary

Amjad Askary has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • IN SITU READOUT OF DNA BARCODES
    Publication number: 20220396833
    Abstract: Disclosed herein include systems, methods, compositions, and kits for in situ readout of barcodes, such as DNA barcodes. Barcode constructs containing a promoter (e.g., a phage promoter) that is inactive in live cells can be integrated in the genomes of cells. Cells can be fixed, and phage RNA polymerase can be used for transcription of the barcode to RNA transcripts. The RNA transcripts can be detected using, for example, fluorescent imaging and used to determine barcode sequences.
    Type: Application
    Filed: August 4, 2022
    Publication date: December 15, 2022
    Inventors: Amjad Askary, Michael B. Elowitz, Mark W. Budde, Carlos Lois, Luis Sanchez Guardado, Long Cai, James Linton
  • In situ readout of DNA barcodes
    Patent number: 11421273
    Abstract: Disclosed herein include systems, methods, compositions, and kits for in situ readout of barcodes, such as DNA barcodes. Barcode constructs containing a promoter (e.g., a phage promoter) that is inactive in live cells can be integrated in the genomes of cells. Cells can be fixed, and phage RNA polymerase can be used for transcription of the barcode to RNA transcripts. The RNA transcripts can be detected using, for example, fluorescent imaging and used to determine barcode sequences.
    Type: Grant
    Filed: December 2, 2019
    Date of Patent: August 23, 2022
    Assignee: California Institute of Technology
    Inventors: Amjad Askary, Michael B. Elowitz, Mark W. Budde, Carlos Lois, Luis Sanchez Guardado, Long Cai, James Linton
  • IN SITU READOUT OF DNA BARCODES
    Publication number: 20200172968
    Abstract: Disclosed herein include systems, methods, compositions, and kits for in situ readout of barcodes, such as DNA barcodes. Barcode constructs containing a promoter (e.g., a phage promoter) that is inactive in live cells can be integrated in the genomes of cells. Cells can be fixed, and phage RNA polymerase can be used for transcription of the barcode to RNA transcripts. The RNA transcripts can be detected using, for example, fluorescent imaging and used to determine barcode sequences.
    Type: Application
    Filed: December 2, 2019
    Publication date: June 4, 2020
    Inventors: Amjad Askary, Michael B. Elowitz, Mark W. Budde, Carlos Lois, Luis Sanchez Guardado, Long Cai, James Linton