Abstract: The present invention relates to pharmaceutical compositions comprising dimethyl fumarate and a pharmaceutically acceptable agent which inhibits the enzyme catalyzed degradation of dimethyl fumarate.

Abstract: The invention discloses a glass lined metal micro-reactor with enhanced heat transfer efficiency in continuous flow operation. More particularly, the invention discloses a glass lined micro-reactor that can be reassembled. The invention provides a novel glass lined metal micro-reactor with micro fluidic channels that provide a better mixing, better heat exchange, and better temperature control. The micro fluidic channels machined in the glass lined metal reactor/mixer may be straight, curved, lamellar, flower shaped, or spiral such that the cross sectional area of the micro fluidic channel is configured to suit the cross sectional area of the micro-reactor.

Abstract: Embodiments of a system and method for secure clock management in a mobile device, or user equipment, are generally described herein. A timer offset may be calculated between a first secure clock time and a first network time. A reset delta based on at least the timer offset may be obtained and a recovered secure clock time based on at least the reset delta may be generated. A one-time password may be generated based on at least the recovered secure clock time.

Abstract: Compounds having formulas (I) to (VIII), salts thereof, or combinations thereof and pharmaceutical compositions comprising one or more these compounds are described herein for the treatment of HIV and neurodegenerative effects caused by HIV. Also provided herein are methods and a kit for inhibiting HIV-1, treating latent HIV in the brain, and preventing HIV-mediated cognitive decline and HIV dementia comprising administering the compounds having the formulas (I) to (VIII) and pharmaceutical compositions comprising the compounds having these formulas. The compounds having formulas I through VIII are curcumin analogs which are advantageously characterized as having anti-retroviral, neuroprotective, anti-glucosidase, and anti-HIV integrase properties. In one aspect, the pharmaceutical composition is delivered intranasally.

Abstract: Embodiments of a system and method for secure clock management in a mobile device, or user equipment, are generally described herein. A timer offset may be calculated between a first secure clock time and a first network time. A reset delta based on at least the timer offset may be obtained and a recovered secure clock time based on at least the reset delta may be generated. A one-time password may be generated based on at least the recovered secure clock time.

Abstract: The present invention is directed to solid stable pharmaceutical fixed dose compositions comprising irbesartan, amlodipine besilate and pharmaceutically acceptable excipients, to their preparation and to their therapeutic application.

Abstract: A fractal impeller design for stirred tank reactors comprising plurality of main branches, each of which further having plurality of sub-branches with each sub branch having plurality of blades to distribute/dissipate energy in uniform manner and to achieve uniform temperature throughout the reactor while operating it at lower impeller speed to avoid high shear zones; wherein, the angular distances covered by the blades vary and yield variation in the local blade passage velocity for a given impeller rotation speed.

Abstract: Compounds having formulas (I) to (VIII), salts thereof, or combinations thereof and pharmaceutical compositions comprising one or more these compounds are described herein for the treatment of HIV and neurodegenerative effects caused by HIV. Also provided herein are methods and a kit for inhibiting HIV-1, treating latent HIV in the brain, and preventing HIV-mediated cognitive decline and HIV dementia comprising administering the compounds having the formulas (I) to (VIII) and pharmaceutical compositions comprising the compounds having these formulas. The compounds having formulas I through VIII are curcumin analogs which are advantageously characterized as having anti-retroviral, neuroprotective, anti-glucosidase, and anti-HIV integrase properties. In one aspect, the pharmaceutical composition is delivered intranasally.

Abstract: In a computing device that includes a host operating system and a management engine separate from the host operating system, if the primary operating system is not operating, a management engine may obtain from a credential server via a first network connection logon information for a secured network and the management engine connects to the secure network through a secured connection using the logon information. If the operating system is operating the operating system provides the logon information to the management engine. Certificate verification may be performed by a remote server on behalf of the management engine. Other embodiments are disclosed and claimed.

Abstract: A method for detecting a human user includes establishing a protected audio video path (PAVP) session between a client device and a server device. The method also includes encrypting the user presence object with keys associated with the PAVP session. The method further includes sending an encrypted user presence object to the client device via the PAVP session. Additionally, the method includes determining whether the human user is in proximity with the client device based on a response associated with the user presence object.

Abstract: Disclosed herein is a continuous tubular reactor based conversion of acetophenones to amino substituted acetophenones wherein the nitration is carried out at ?10 to 10° C. followed by reduction to m-nitrophenone resulting in uniform output of product, said process comprising the steps of: a) Nitrating acetophenone with nitrating agent (nitration mixture or fuming nitric acid) at ?10 to 10° C.; b) Isolating m-nitro acetophenone from a mixture of o and m-nitro acetophenone and c) Reducing the m-nitro to obtain m-amino acetophenone.

Abstract: Compounds having formulas (I) to (VIII), salts thereof, or combinations thereof and pharmaceutical compositions comprising one or more these compounds are described herein for the treatment of HIV and neurodegenerative effects caused by HIV. Also provided herein are methods and a kit for inhibiting HIV-1, treating latent HIV in the brain, and preventing HIV-mediated cognitive decline and HIV dementia comprising administering the compounds having the formulas (I) to (VIII) and pharmaceutical compositions comprising the compounds having these formulas. The compounds having formulas I through VIII are curcumin analogs which are advantageously characterized as having anti-retroviral, neuroprotective, anti-glucosidase, and anti-HIV integrase properties. In one aspect, the pharmaceutical composition is delivered intranasally.

Abstract: A fractal impeller design for stirred tank reactors comprising plurality of main branches, each of which further having plurality of sub-branches with each sub branch having plurality of blades to distribute/dissipate energy in uniform manner and to achieve uniform temperature throughout the reactor while operating it at lower impeller speed to avoid high shear zones; wherein, the angular distances covered by the blades vary and yield variation in the local blade passage velocity for a given impeller rotation speed.

Abstract: Systems and methods according to various embodiments disclose a worker process manager adapted to spawn one or more worker processes on a server and to load an application on each of the worker processes. The worker process manager is adapted to isolate the one or more worker processes from each other and to control resource usage by the worker processes. A resource manager is adapted to detect applications that overuse system resources. The worker process manager is adapted to isolate worker processes and to control resource usage using one or more of the following techniques: least-privilege execution, messaging isolation, credentials isolation, data isolation, network isolation, fair share resource usage, and managed runtime security. Heuristic algorithms are used to detect applications that frequently overuse system resources that are unchargeable and that cause system unresponsiveness.

Abstract: A container service is capable of hosting large numbers of middleware components for multiple tenants. A central container manager controls a plurality of compute nodes. The central container manager receives middleware components from external devices or services and assigns the components to containers on one or more designated compute nodes. Each compute node has a container management agent and one or more containers. The container management agents activate and manage the appropriate number of containers to run the assigned middleware components. The container management agent assigns each container on its compute node a limited set of privileges to control access to shared resources. The central container manager and each node's container management agent monitor container load levels and dynamically adjust the placement of the middleware components to maintain balanced operation. The compute nodes are grouped into clusters based upon the type of middleware components hosted on each compute node.

Abstract: The present invention is directed to solid stable pharmaceutical fixed dose compositions comprising ramipril, amlodipine besilate and pharmaceutically acceptable excipients, and to their preparation.

Abstract: In a computing device that includes a host operating system and a management engine separate from the host operating system, if the primary operating system is not operating, a management engine may obtain from a credential server via a first network connection logon information for a secured network and the management engine connects to the secure network through a secured connection using the logon information. If the operating system is operating the operating system provides the logon information to the management engine. Certificate verification may be performed by a remote server on behalf of the management engine. Other embodiments are disclosed and claimed.

Abstract: In an embodiment, a method includes registering applications and network services for notification of an out-of-band introduction, and using the out-of-band introduction to bootstrap secure in-band provisioning of credentials and policies that are used to control subsequent access and resource sharing on an in-band channel. In another embodiment, an apparatus implements the method.

Abstract: In one embodiment a controller comprises logic to receive a request for a credential to authenticate a user for a transaction, in response to a determination that a credential which satisfies the request resides on a memory module, execute an authentication routine to authenticate a user of the controller, in response to a successful authentication, retrieve the credential from the memory module, and provide a token to certify the credential in response to the request. Other embodiments may be described.

Abstract: A container service is capable of hosting large numbers of middleware components for multiple tenants. A central container manager controls a plurality of compute nodes. The central container manager receives middleware components from external devices or services and assigns the components to containers on one or more designated compute nodes. Each compute node has a container management agent and one or more containers. The container management agents activate and manage the appropriate number of containers to run the assigned middleware components. The container management agent assigns each container on its compute node a limited set of privileges to control access to shared resources. The central container manager and each node's container management agent monitor container load levels and dynamically adjust the placement of the middleware components to maintain balanced operation. The compute nodes are grouped into clusters based upon the type of middleware components hosted on each compute node.