Patents by Inventor Amos Maritan

Amos Maritan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Intracellular antibodies
    Patent number: 7608453
    Abstract: A method of identifying at least one consensus sequence for an intracellular antibody (ICS) comprising the steps of: creating a database comprising sequences of validated intracellular antibodies (VIDA database) and aligning the sequences of validated intracellular antibodies according to Kabat; determining the frequency with which a particular amino acid occurs in each of the positions of the aligned antibodies; selecting a frequency threshold value (LP or consensus threshold) in the range from 70% to 100%; identifying the positions of the alignment at which the frequency of a particular amino acid is greater than or equal to the LP value; and identifying the most frequent amino acid, in the position of said alignment.
    Type: Grant
    Filed: February 3, 2004
    Date of Patent: October 27, 2009
    Inventors: Antonino Cattaneo, Amos Maritan, Michela Visintin, Terrence Rabbitts, Giovanni Settanni
  • Intracellular antibodies
    Publication number: 20050288864
    Abstract: A method of identifying at least one consensus sequence for an intracellular antibody (ICS) comprising the steps of: creating a database comprising sequences of validated intracellular antibodies (VIDA database) and aligning the sequences of validated intracellular antibodies according to Kabat; determining the frequency with which a particular amino acid occurs in each of the positions of the aligned antibodies; selecting a frequency threshold value (LP or consensus threshold) in the range from 70% to 100%; identifying the positions of the alignment at which the frequency of a particular amino acid is greater than or equal to the LP value; and identifying the most frequent amino acid, in the position of said alignment.
    Type: Application
    Filed: February 3, 2004
    Publication date: December 29, 2005
    Inventors: Antonino Cattaneo, Amos Maritan, Michela Visintin, Terrence Rabbitts, Giovanni Settanni