Patents by Inventor Amy A. Twite

Amy A. Twite has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250213704
    Abstract: The present disclosure is directed to peptide-polymer conjugates, and their use in treating cancers, such as solid tumors.
    Type: Application
    Filed: March 21, 2023
    Publication date: July 3, 2025
    Inventors: Wesley M. JACKSON, Livia W. BRIER, Amy A. TWITE, Adam BARNEBEY
  • Publication number: 20230405133
    Abstract: The present invention relates to purified hyaluronic acid conjugates comprising biologically active peptides. The invention further relates to pharmaceutical compositions of the conjugates, and methods of preparing them.
    Type: Application
    Filed: April 14, 2023
    Publication date: December 21, 2023
    Inventors: Wesley M. JACKSON, Amy A. TWITE, Adam BARNEBEY, Livia Wilz BRIER, Jesse M. MCFARLAND
  • Publication number: 20230406916
    Abstract: The present invention relates to peptide sequences having a high degree of humanness and/or the ability to be expressed in appreciable levels in culture media, such as in E. coli. The peptides can be covalently attached via an alpha-helical peptide linker to a polymer backbone. The invention further relates to methods of preparing the peptides, polymer conjugates comprising the peptides, and pharmaceutical compostions thereof.
    Type: Application
    Filed: April 14, 2023
    Publication date: December 21, 2023
    Inventors: Wesley M. JACKSON, Amy A. TWITE, Adam BARNEBEY, Livia Wilz BRIER, Jesse M. MCFARLAND
  • Publication number: 20220251185
    Abstract: The present disclosure is directed to peptide-polymer conjugates utilizing hydrophilic linkers, and their use in treating diseases or disorders. In one embodiment, the present invention provides a conjugate of Formula I: (X—Y)n-Z Formula (I) wherein each X is independently a peptide having a molecular weight of from about 5 kDa to about 200 kDa; each Y is independently a hydrophilic linker; Z is a biocompatible polymer having a molecular weight of from about 0.1 MDa to about 3 MDa; and subscript n is an integer from 10 to 1000.
    Type: Application
    Filed: July 1, 2020
    Publication date: August 11, 2022
    Inventors: Wesley M. JACKSON, Amy A. TWITE, Livia Wilz BRIER
  • Patent number: 10744207
    Abstract: The disclosure provides complexes comprising targeting units, methods for their production, and methods for their use. In some embodiments, complexes comprise therapeutic agents complexed with targeting units. In some embodiments, complexes comprise cells complexed with targeting units. In view of the foregoing, there is a need for improved modalities for targeting of therapeutics, in the area of immunotherapy and others. The present disclosure addresses these needs, and provides additional advantages as well.
    Type: Grant
    Filed: May 1, 2015
    Date of Patent: August 18, 2020
    Assignee: ACEPODIA, INC.
    Inventors: Amy A. Twite, Ching-Wen Hsiao, Sonny Hsiao, Cheng Liu, Hong Liu
  • Patent number: 10124312
    Abstract: The disclosure relates to methods of photopatterning molecules directly on a surface by photochemical means.
    Type: Grant
    Filed: June 3, 2015
    Date of Patent: November 13, 2018
    Assignee: The Regents of the University of California
    Inventors: Matthew B. B. Francis, Amy A. Twite, Kareem El Muslemany
  • Publication number: 20180133341
    Abstract: The disclosure provides complexes comprising targeting units, methods for their production, and methods for their use. In some embodiments, complexes comprise therapeutic agents complexed with targeting units. In some embodiments, complexes comprise cells complexed with targeting units. In view of the foregoing, there is a need for improved modalities for targeting of therapeutics, in the area of immunotherapy and others. The present disclosure addresses these needs, and provides additional advantages as well.
    Type: Application
    Filed: May 1, 2015
    Publication date: May 17, 2018
    Applicants: ADHEREN INCORPORATED
    Inventors: Amy A. TWITE, Ching-Wen HSIAO, Sonny HSIAO, Cheng LIU, Hong LIU
  • Publication number: 20150343413
    Abstract: The disclosure relates to methods of photopatterning molecules directly on a surface by photochemical means.
    Type: Application
    Filed: June 3, 2015
    Publication date: December 3, 2015
    Inventors: Matthew B. Francis, Amy A. Twite, Kareem El Muslemany