Abstract: This application is related to an apparatus and method for improving venous blood flow in mobility-impaired patients. In one aspect, the apparatus is a motorized or powered rocking chair with a footplate. The rocking chair and footplate rotate through physiologically relevant ranges of motion either at the same frequency or at different frequencies in order to mechanically induce a calf muscle pump action in the dependent legs of a mobility-impaired patient. Artificially inducing the calf muscle pump action in such patients acts to boost the action of the heart and lessen blood pooling in the lower extremities of the legs.

Abstract: A backpack for providing improved user access points. In particular a backpack providing for side entry into the contents. The backpack may utilize an S-shape zipper to improve access. The backpack may have multiple ways to access the inner pocket, including top access and dual side access.

Abstract: This application is related to an apparatus and method for improving venous blood flow in mobility-impaired patients. In one aspect, the apparatus is a motorized or powered rocking chair with a footplate. The rocking chair and footplate rotate through physiologically relevant ranges of motion either at the same frequency or at different frequencies in order to mechanically induce a calf muscle pump action in the dependent legs of a mobility-impaired patient. Artificially inducing the calf muscle pump action in such patients acts to boost the action of the heart and lessen blood pooling in the lower extremities of the legs.

Abstract: Compositions, systems and methods of sequencing are disclosed, where the compositions and systems include polymerase enzymes that have been genetically modified to more efficiently incorporate nucleotides including labels having a detectable properties that are released during incorporation, to augment a rate of labeled nucleotide incorporation, to augment a rate of pyrophosphate release, or to augment two or more of these properties and rates. Also disclosed are terminally labeled and dual labeled nucleotides, and click-chemistry based methods of synthesizing the same.

Abstract: A backpack for providing improved user access points. In particular a backpack providing for side entry into the contents. The backpack may utilize an S-shape zipper to improve access. The backpack may have multiple ways to access the inner pocket, including top access and dual side access.

Abstract: A novel and efficient single pot synthetic schemes are disclosed for preparing modified nucleotides, nucleotide analogs, nucleotide polyphosphates, and nucleotide polyphosphate analogs. The novel method is used to prepare nucleotides, nucleotide analogs, nucleotide polyphosphates, and nucleotide polyphosphate analogs having non-persistent or persistent and non-persistent modifications. Novel biomolecular reactions are also disclosed using the novel modified biomolecules disclosed herein.