Abstract: Provided herein are compounds according to Formula (I) or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3, R5, and R7 are defined herein. Also provided herein are pharmaceutical compositions comprising a compound of Formula (I) as well as the use of such compounds as M4 receptor agonists.

Abstract: Provided are computing systems, methods, and platforms that automatically produce production-ready machine learning models and deployment pipelines from minimal input information such as a raw training dataset. In particular, one example computing system can import a training dataset associated with a user. The computing system can execute an origination machine learning pipeline to perform a model architecture search that selects and trains a machine learning model for the training dataset. Execution of the origination machine learning pipeline can also result in generation of a deployment machine learning pipeline configured to enable deployment of the machine learning model (e.g., running the machine learning model to produce inferences and/or optionally other tasks such as re-training and/or re-tuning the model).

Abstract: The present invention is directed to a crutch/cane assembly that can be converted from a crutch into a cane, or vice-versa. The crutch/cane assembly has first and second elongated members, an arm support connected to the upper portions of the first and second elongated members, and an inner member connected to the first and second elongated members on opposing sides of the inner member. A removable cane member has a grip having a first and second end where at least one of the first and second ends is removably attached to the first and second elongated members, and at least one hole. A foot member is telescopically inserted into the inner member and the removable cane member, and detachably connected to the cane member via at least one spring-loaded pin that is inserted into at least one hole of the removable cane member.