Patents by Inventor Amy Donate

Amy Donate has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Electromanipulation of cells and other biological tissues by pulsed electric fields at elevated temperatures
    Patent number: 10660693
    Abstract: Systems and methods for treatment of a biological tissues including target tissues and other tissues. The method includes elevating a temperature of the target tissues above a physiological temperature of the biological tissues to treatment temperature, and generating an electric field extending through at least a portion of the target tissues using a pre-defined sequence of short voltage pulses applied between at least two electrodes. In the method, the treatment temperature is maintained during the generating. Further, the pre-defined sequence is selected such that a magnitude of the electric field generated is sufficient to induce electromanipulation in the portion of the target tissues without substantially elevating of the temperature of the portion of the target tissues above the treatment temperature.
    Type: Grant
    Filed: August 7, 2018
    Date of Patent: May 26, 2020
    Assignee: Old Dominion University Research Foundation
    Inventors: Karl H. Schoenbach, Richard Heller, James Camp, Stephen P. Beebe, Shu Xiao, Amy Donate
  • ELECTROMANIPULATION OF CELLS AND OTHER BIOLOGICAL TISSUES BY PULSEDELECTRIC FIELDS AT ELEVATED TEMPERATURES
    Publication number: 20190038337
    Abstract: Systems and methods for treatment of a biological tissues including target tissues and other tissues. The method includes elevating a temperature of the target tissues above a physiological temperature of the biological tissues to treatment temperature, and generating an electric field extending through at least a portion of the target tissues using a pre-defined sequence of short voltage pulses applied between at least two electrodes. In the method, the treatment temperature is maintained during the generating. Further, the pre-defined sequence is selected such that a magnitude of the electric field generated is sufficient to induce electromanipulation in the portion of the target tissues without substantially elevating of the temperature of the portion of the target tissues above the treatment temperature.
    Type: Application
    Filed: August 7, 2018
    Publication date: February 7, 2019
    Inventors: Karl H. SCHOENBACH, Richard HELLER, James CAMP, Stephen P. BEEBE, Shu XIAO, Amy DONATE
  • Electromanipulation of cells and other biological tissues by pulsed electric fields at elevated temperatures
    Patent number: 10070914
    Abstract: Systems and methods for treatment of a biological tissues comprising target tissues and other tissues. The method includes elevating a temperature of the target tissues above a physiological temperature of the biological tissues to treatment temperature, and generating an electric field extending through at least a portion of the target tissues using a pre-defined sequence of short voltage pulses applied between at least two electrodes. In the method, the treatment temperature is maintained during the generating. Further, the pre-defined sequence is selected such that a magnitude of the electric field generated is sufficient to induce electromanipulation in the portion of the target tissues without substantially elevating of the temperature of the portion of the target tissues above the treatment temperature.
    Type: Grant
    Filed: December 20, 2012
    Date of Patent: September 11, 2018
    Assignee: Old Dominion University Research Foundation
    Inventors: Karl H. Schoenbach, Richard Heller, James Camp, Stephen P. Beebe, Shu Xiao, Amy Donate
  • ELECTROMANIPULATION OF CELLS AND OTHER BIOLOGICALTISSUES BY PULSED ELECTRIC FIELDS AT ELEVATED TEMPERATURES
    Publication number: 20140364797
    Abstract: Systems and methods for treatment of a biological tissues comprising target tissues and other tissues. The method includes elevating a temperature of the target tissues above a physiological temperature of the biological tissues to treatment temperature, and generating an electric field extending through at least a portion of the target tissues using a pre-defined sequence of short voltage pulses applied between at least two electrodes. In the method, the treatment temperature is maintained during the generating. Further, the pre-defined sequence is selected such that a magnitude of the electric field generated is sufficient to induce electromanipulation in the portion of the target tissues without substantially elevating of the temperature of the portion of the target tissues above the treatment temperature.
    Type: Application
    Filed: December 20, 2012
    Publication date: December 11, 2014
    Inventors: Karl H. Schoenbach, Richard Heller, James Camp, Stephen P. Beebe, Shu Xiao, Amy Donate