Patents by Inventor Amy E. Keating

Amy E. Keating has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Selective MENA binding peptides
    Patent number: 12552834
    Abstract: Peptides that selectively bind ENAH (MENA) are described. The peptides are useful for treating certain cancers, such as triple negative breast cancer and for reducing resistance to taxane therapy.
    Type: Grant
    Filed: January 25, 2022
    Date of Patent: February 17, 2026
    Assignees: MASSACHUSETTS INSTITUTE OF TECHNOLOGY, ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA
    Inventors: Theresa Hwang, Amy E. Keating, Meucci Ilunga, Sara Parker, Ghassan Mouneimne, Samantha Hill
  • SELECTIVE MENA BINDING PEPTIDES
    Publication number: 20240101604
    Abstract: Peptides that selectively bind ENAH (MENA) are described. The peptides are useful for treating certain cancers, such as triple negative breast cancer and for reducing resistance to taxane therapy.
    Type: Application
    Filed: January 25, 2022
    Publication date: March 28, 2024
    Inventors: Theresa Hwang, Amy E. Keating, Meucci Ilunga, Sara Parker, Ghassan Mouneimne, Samantha Hill
  • SELECTIVE MCL-1 BINDING PEPTIDES
    Publication number: 20240092849
    Abstract: Provided herein are peptides that bind Mcl-1. Also provided are compositions containing these polypeptides and methods of using such peptides in the treatment of cancer that include administering to a subject one of the polypeptides.
    Type: Application
    Filed: April 3, 2023
    Publication date: March 21, 2024
    Inventors: Raheleh Rezaei-Araghi, Amy E. Keating
  • Peptides selective for Bcl-2 family proteins
    Patent number: 11286299
    Abstract: Provided herein are peptides selective for combinations of Mcl-1/Bfl-1/Bcl-xL. Also provided are compositions containing these polypeptides and methods of using such peptides in the treatment of cancer that include administering to a subject one of the polypeptides.
    Type: Grant
    Filed: September 17, 2019
    Date of Patent: March 29, 2022
    Assignees: Massachusetts Institute of Technology, Trustees of Darthmouth College
    Inventors: Vincent Xue, Justin Michael Jenson, Amy E. Keating, Jianfu Zhou, Gevorg Grigoryan
  • PEPTIDES SELECTIVE FOR BCL-2 FAMILY PROTEINS
    Publication number: 20200262914
    Abstract: Provided herein are peptides selective for combinations of Mcl-1/Bfl-1/Bc1-xL. Also provided are compositions containing these polypeptides and methods of using such peptides in the treatment of cancer that include administering to a subject one of the polypeptides.
    Type: Application
    Filed: September 17, 2019
    Publication date: August 20, 2020
    Inventors: Vincent Xue, Justin Michael Jenson, Amy E. Keating, Jianfu Zhou, Gevorg Grigoryan