Patents by Inventor Amy Frederick

Amy Frederick has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Treatment of Dry Age-Related Macular Degeneration
    Publication number: 20240401082
    Abstract: The present disclosure provides gene therapy that targets complement pathways for treating dry age-related macular degeneration.
    Type: Application
    Filed: March 15, 2024
    Publication date: December 5, 2024
    Applicant: Genzyme Corporation
    Inventors: Matthew Adamowicz, Hao Chen, Amy Frederick, Christian Mueller, Catherine O’Riordan, Vaishnavi Rajagopal, John C. Reed, Michael John Storek
  • MODIFIED ADENO-ASSOCIATED VIRAL CAPSID PROTEINS FOR OCULAR GENE THERAPY AND METHODS OF USE THEREOF
    Publication number: 20210261625
    Abstract: Provided herein are modified adeno-associated viral (AAV) capsid proteins, compositions (e.g., rAAV) comprising the capsid proteins, and nucleic acids encoding the capsid proteins. The AAV capsids provided herein confer retinal cell tropism and/or corneal cell tropism, and mediate improved transduction efficiency in clinically relevant ocular cell types such as photoreceptors and/or corneal endothelial cells. Also provided are nucleic acids encoding the capsid proteins, and AAV particles comprising the capsid proteins.
    Type: Application
    Filed: January 29, 2021
    Publication date: August 26, 2021
    Inventors: Amy Frederick, Xiaoying Jin, Lin Liu, Catherine O'Riordan, Jennifer Sullivan