Patents by Inventor Amy Hiddessen

Amy Hiddessen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Detection of nuclease edited sequences in automated modules and instruments
    Patent number: 11685889
    Abstract: The present disclosure provides automated modules and instruments for improved detection of nuclease genome editing of live cells. The disclosure provides improved modules—including high throughput modules—for screening cells that have been subjected to editing and identifying and selecting cells that have been properly edited.
    Type: Grant
    Filed: April 30, 2022
    Date of Patent: June 27, 2023
    Assignee: INSCRIPTA, INC.
    Inventors: Andrew Garst, Richard Fox, Eileen Spindler, Amy Hiddessen, Phillip Belgrader, Don Masquelier, Bruce Chabansky, Michael Graige
  • DETECTION OF NUCLEASE EDITED SEQUENCES IN AUTOMATED MODULES AND INSTRUMENTS
    Publication number: 20220259543
    Abstract: The present disclosure provides automated modules and instruments for improved detection of nuclease genome editing of live cells. The disclosure provides improved modules—including high throughput modules—for screening cells that have been subjected to editing and identifying and selecting cells that have been properly edited.
    Type: Application
    Filed: April 30, 2022
    Publication date: August 18, 2022
    Inventors: Andrew Garst, Richard Fox, Eileen Spindler, Amy Hiddessen, Phillip Belgrader, Don Masquelier, Bruce Chabansky, Michael Graige
  • Detection of nuclease edited sequences in automated modules and instruments
    Patent number: 11365383
    Abstract: The present disclosure provides automated modules and instruments for improved detection of nuclease genome editing of live cells. The disclosure provides improved modules—including high throughput modules—for screening cells that have been subjected to editing and identifying and selecting cells that have been properly edited.
    Type: Grant
    Filed: February 21, 2022
    Date of Patent: June 21, 2022
    Assignee: Inscripta, Inc.
    Inventors: Eileen Spindler, Amy Hiddessen, Andrew Garst, Michael Graige, Richard Fox, Phillip Belgrader, Don Masquelier, Bruce Chabansky
  • DETECTION OF NUCLEASE EDITED SEQUENCES IN AUTOMATED MODULES AND INSTRUMENTS
    Publication number: 20220177826
    Abstract: The present disclosure provides automated modules and instruments for improved detection of nuclease genome editing of live cells. The disclosure provides improved modules—including high throughput modules—for screening cells that have been subjected to editing and identifying and selecting cells that have been properly edited.
    Type: Application
    Filed: February 21, 2022
    Publication date: June 9, 2022
    Inventors: Eileen Spindler, Amy Hiddessen, Andrew Garst, Michael Graige, Richard Fox, Phillip Belgrader, Don Masquelier, Bruce Chabansky
  • Detection of nuclease edited sequences in automated modules and instruments
    Patent number: 11268061
    Abstract: The present disclosure provides automated modules and instruments for improved detection of nuclease genome editing of live cells. The disclosure provides improved modules—including high throughput modules—for screening cells that have been subjected to editing and identifying and selecting cells that have been properly edited.
    Type: Grant
    Filed: August 13, 2021
    Date of Patent: March 8, 2022
    Assignee: Inscripta, Inc.
    Inventors: Andrew Garst, Michael Graige, Richard Fox, Eileen Spindler, Amy Hiddessen, Phillip Belgrader, Don Masquelier, Bruce Chabansky
  • DETECTION OF NUCLEASE EDITED SEQUENCES IN AUTOMATED MODULES AND INSTRUMENTS
    Publication number: 20210371799
    Abstract: The present disclosure provides automated modules and instruments for improved detection of nuclease genome editing of live cells. The disclosure provides improved modules—including high throughput modules—for screening cells that have been subjected to editing and identifying and selecting cells that have been properly edited.
    Type: Application
    Filed: August 13, 2021
    Publication date: December 2, 2021
    Inventors: Andrew Garst, Michael Graige, Richard Fox, Eileen Spindler, Amy Hiddessen, Phillip Belgrader, Don Masquelier, Bruce Chabansky
  • Detection of nuclease edited sequences in automated modules and instruments
    Patent number: 11142740
    Abstract: The present disclosure provides automated modules and instruments for improved detection of nuclease genome editing of live cells. The disclosure provides improved modules—including high throughput modules—for screening cells that have been subjected to editing and identifying and selecting cells that have been properly edited.
    Type: Grant
    Filed: August 8, 2019
    Date of Patent: October 12, 2021
    Assignee: Inscripta, Inc.
    Inventors: Andrew Garst, Michael Graige, Richard Fox, Eileen Spindler, Amy Hiddessen, Phillip Belgrader, Don Masquelier, Bruce Chabansky
  • DETECTION OF NUCLEASE EDITED SEQUENCES IN AUTOMATED MODULES AND INSTRUMENTS
    Publication number: 20200056139
    Abstract: The present disclosure provides automated modules and instruments for improved detection of nuclease genome editing of live cells. The disclosure provides improved modules—including high throughput modules—for screening cells that have been subjected to editing and identifying and selecting cells that have been properly edited.
    Type: Application
    Filed: August 8, 2019
    Publication date: February 20, 2020
    Inventors: Andrew Garst, Michael Graige, Richard Fox, Eileen Spindler, Amy Hiddessen, Phillip Belgrader, Don Masquelier, Bruce Chabansky
  • DETECTION OF NUCLEASE EDITED SEQUENCES IN AUTOMATED MODULES AND INSTRUMENTS VIA BULK CELL CULTURE
    Publication number: 20200056192
    Abstract: The present disclosure provides methods, automated modules, and instruments for enrichment of live cells that have been edited by nucleic acid-guided nuclease genome editing. The disclosure provides improved methods and modules—including high throughput methods and modules—for enriching for cells that have been subjected to editing.
    Type: Application
    Filed: August 14, 2019
    Publication date: February 20, 2020
    Inventors: Eileen Spindler, Amy Hiddessen, Phillip Belgrader, Charles Johnson, Clint Davis
  • COMPOSITIONS, METHODS AND SYSTEMS FOR POLYMERASE CHAIN REACTION ASSAYS
    Publication number: 20140302503
    Abstract: The present disclosure provides methods, devices, systems and compositions for detecting nucleic acids in polymerase chain reaction assays, such as droplet digital polymerase chain reaction (ddPCR) assays. The present disclosure provides methods, devices, systems and compositions for detecting nucleic acids in ddPCR assays using intercalating dyes. A dual surfactant system with at least one fluorosurfactant and at least one non-ionic non-fluorosurfactant may be employed for droplet generation and nucleic acid detection.
    Type: Application
    Filed: March 7, 2014
    Publication date: October 9, 2014
    Inventors: Adam Lowe, Geoff McDermott, Chris Hindson, Erin Chia, Amy Hiddessen, Ben Hindson, Chunxiao Han, Yaqi Wang
  • STABILIZED DROPLETS FOR CALIBRATION AND TESTING
    Publication number: 20140134623
    Abstract: Provided herein, are droplet mixture compositions and systems and methods for forming mixtures of droplets. The system may comprise two or more droplet generation units. Each unit may include at least one first input well, a second input well, and an output well connected to the first and second input wells by channels that form a droplet generator. The combined droplet populations can be mixed, heated, and collected for multiple uses, such as for use as calibration standards for instrument testing and analysis.
    Type: Application
    Filed: June 19, 2013
    Publication date: May 15, 2014
    Inventors: Amy Hiddessen, Erin Steenblock