Abstract: Peptides that selectively bind ENAH (MENA) are described. The peptides are useful for treating certain cancers, such as triple negative breast cancer and for reducing resistance to taxane therapy.

Abstract: A system and method are provided for conducting a primary lottery game in conjunction with a televised game show and a play-at-home version of the show. In the primary lottery game, players purchase lottery tickets, with each ticket having a unique web code. Players of the primary lottery game become eligible to be a contestant in the show by accumulating a predefined set of game symbols in the lottery game. During broadcast of the game show, a plurality of game symbol codes are provided to at-home viewers of the show who are also players of the primary lottery game. The at-home viewers are able to access a website, enter the web code from their lottery ticket, enter one the game symbol codes broadcast with the game show, and play a web-based game to win a game symbol associated with the entered game symbol code.

Abstract: A system and related method for conducting a lottery game having a televised bonus game component calls for establishing a primary lottery game wherein players are issued lottery tickets. The primary lottery game has a bonus game component and the lottery tickets have a bonus game symbol thereon. For entry into the bonus game, the players are required to collect a predefined set of the bonus game symbols. Periodically, a bonus game drawing is conducted such that at least one of the players entered in the drawing is selected as a winner in each bonus game drawing and becomes eligible for further participation in the bonus game. The bonus game component is coordinated with a televised game show so that contestants in the televised game show are the selected winners from the bonus game drawings. A prize is awarded to winning contestants who competed in the televised game show.

Abstract: A system and method are provided for conducting a lottery game in conjunction with a televised game show and a play-at-home version of the televised game show. A primary lottery game is established wherein players purchase lottery tickets having a unique web code assigned thereto. Players of the primary lottery game become eligible to be contestants in the televised game show by satisfying a condition of the primary lottery game. During broadcast of the televised game show, an access code is provided to at-home viewers of the show who are also players of the primary lottery game. The access code enables the at-home viewers to access a website, enter the web code from their lottery ticket, enter the access code broadcast with the televised game show, and play a web-based game to win a prize award.

Abstract: A system and method are provided for conducting a primary lottery game in conjunction with a televised game show and a play-at-home version of the show. In the primary lottery game, players purchase lottery tickets, with each ticket having a unique web code. Players of the primary lottery game become eligible to be a contestant in the show by accumulating a predefined set of game symbols in the lottery game. During broadcast of the game show, a plurality of game symbol codes are provided to at-home viewers of the show who are also players of the primary lottery game. The at-home viewers are able to access a website, enter the web code from their lottery ticket, enter one the game symbol codes broadcast with the game show, and play a web-based game to win a game symbol associated with the entered game symbol code.

Abstract: A method and associated lottery game card/ticket are provided for implementing a ticket-based, multi-component lottery game and includes providing lottery tickets for players, wherein the lottery tickets include a first game component with a first prize structure and at least one additional game component with a separate second prize structure. A first validation code is provided on the lottery ticket that is linked to a first game server for validating and redeeming the first game component of the lottery ticket. A second validation code is provided on the lottery ticket that may be linked to a separate second game server for validating and redeeming the second game component of the lottery ticket. Validation and redemption of the lottery ticket for the first and second game components is enabled by separate redemption acts.

Abstract: A method is provided for implementing a Digital Gate-based, multi-player lottery game by providing lottery tickets for players that may include a first game component with a first prize structure and an entry into a multi-player network wherein a plurality of players combine their respective entries to complete a multi-player game, such as a puzzle. Upon successful conclusion of the multi-player game, the players are awarded a prize separate from the first prize structure. A code is provided on the lottery ticket that enables the player to access a designated Internet website and place their entry into at least one of a plurality of ongoing multi-player games with other players. Respective validation files associated with the lottery ticket codes are updated to reflect prizes won in the multi-player games, wherein players may present the lottery ticket and assigned code if required for redemption in the multi-player game.

Abstract: A method is provided for implementing a Digital Gate enabled lottery game wherein players are offered the chance to increase the prize value of a ticket by linking subsequently purchased tickets in a chain. Lottery tickets are provided for players, wherein each lottery ticket includes a unique validation code and play of the game enabled by the lottery ticket may result in a prize within a given prize structure. For winning plays of one of the lottery tickets, consumers are provided an option to redeem the ticket for the prize or to register and designate the winning lottery ticket as part of a chain. The player may enhance the prize associated with the first ticket in the chain by subsequent registration of an additional lottery ticket wherein, upon being registered, the additionally registered tickets in the chain may or may-not be individually redeemed.

Abstract: A method is provided for implementing a ticket-based Internet lottery game wherein winning plays of the Internet games are validated and redeemed through a lottery authority's existing validation and redemption system for on-line lottery tickets. Lottery tickets are provided for players, with the lottery tickets having a code that enables a player to access a designated web site and play an Internet game having a prize structure. The code is validated against a database and, for winning plays of the Internet game, a virtual bet is generated and transferred to the on-line lottery ticket validation system. Virtual drawings are periodically conducted within the on-line lottery ticket validation system in order to load win files corresponding to winning plays of the Internet game into the on-line lottery ticket winners database. The winning players are instructed as to a time after the virtual drawing when they can redeem their prize.

Abstract: A method and associated lottery game card/ticket are provided for implementing a ticket-based, multi-component lottery game and includes providing lottery tickets for players, wherein the lottery tickets include a first game component with a first prize structure and at least one additional game component with a separate second prize structure. A first validation code is provided on the lottery ticket that is linked to a first game server for validating and redeeming the first game component of the lottery ticket. A second validation code is provided on the lottery ticket that may be linked to a separate second game server for validating and redeeming the second game component of the lottery ticket. Validation and redemption of the lottery ticket for the first and second game components is enabled by separate redemption acts.

Abstract: A method is provided for implementing a Digital Gate enabled lottery game wherein players are offered the chance to increase the prize value of a ticket by linking subsequently purchased tickets in a chain. Lottery tickets are provided for players, wherein each lottery ticket includes a unique validation code and play of the game enabled by the lottery ticket may result in a prize within a given prize structure. For winning plays of one of the lottery tickets, consumers are provided an option to redeem the ticket for the prize or to register and designate the winning lottery ticket as part of a chain. The player may enhance the prize associated with the first ticket in the chain by subsequent registration of an additional lottery ticket wherein, upon being registered, the additionally registered tickets in the chain may or may-not be individually redeemed.

Abstract: A method and associated lottery game card/ticket are provided for implementing a ticket-based, multi-component lottery game and includes providing lottery tickets for players, wherein the lottery tickets include a first game component with a first prize structure and at least one additional game component with a separate second prize structure. A first validation code is provided on the lottery ticket that is linked to a first game server for validating and redeeming the first game component of the lottery ticket. A second validation code is provided on the lottery ticket that may be linked to a separate second game server for validating and redeeming the second game component of the lottery ticket. Validation and redemption of the lottery ticket for the first and second game components is enabled by separate redemption acts.

Abstract: A method is provided for implementing a Digital Gate enabled lottery game wherein players are offered the chance to increase the prize value of a ticket by linking subsequently purchased tickets in a chain. Lottery tickets are provided for players, wherein each lottery ticket includes a unique validation code and play of the game enabled by the lottery ticket may result in a prize within a given prize structure. For winning plays of one of the lottery tickets, consumers are provided an option to redeem the ticket for the prize or to register and designate the winning lottery ticket as part of a chain. The player may enhance the prize associated with the first ticket in the chain by subsequent registration of an additional lottery ticket wherein, upon being registered, the additionally registered tickets in the chain may or may-not be individually redeemed.

Abstract: A system and method for conducting a lottery game at a retail establishment wherein players purchase goods or services involve a player placing a wager that is a function of the purchase price of the goods or services purchased at the retail establishment. A lottery draw is conducted at the time of purchase of the goods or services, or at a later time, wherein the probability of winning the draw is a function of the amount of the wager. For a winning draw, the player is awarded a prize that is a function of the purchase price of the goods or services.

Abstract: A method and associated lottery game card/ticket are provided for implementing a ticket-based, multi-component lottery game and includes providing lottery tickets for players, wherein the lottery tickets include a first game component with a first prize structure and at least one additional game component with a separate second prize structure. A first validation code is provided on the lottery ticket that is linked to a first game server for validating and redeeming the first game component of the lottery ticket. A second validation code is provided on the lottery ticket that may be linked to a separate second game server for validating and redeeming the second game component of the lottery ticket. Validation and redemption of the lottery ticket for the first and second game components is enabled by separate redemption acts.

Abstract: A method is provided for implementing a Digital Gate-based, multi-player lottery game by providing lottery tickets for players that may include a first game component with a first prize structure and an entry into a multi-player network wherein a plurality of players combine their respective entries to complete a multi-player game, such as a puzzle. Upon successful conclusion of the multi-player game, the players are awarded a prize separate from the first prize structure. A code is provided on the lottery ticket that enables the player to access a designated Internet website and place their entry into at least one of a plurality of ongoing multi-player games with other players. Respective validation files associated with the lottery ticket codes are updated to reflect prizes won in the multi-player games, wherein players may present the lottery ticket and assigned code if required for redemption in the multi-player game.

Abstract: A method is provided for implementing a Digital Gate enabled lottery game wherein players are offered the chance to increase the prize value of a ticket by linking subsequently purchased tickets in a chain. Lottery tickets are provided for players, wherein each lottery ticket includes a unique validation code and play of the game enabled by the lottery ticket may result in a prize within a given prize structure. For winning plays of one of the lottery tickets, consumers are provided an option to redeem the ticket for the prize or to register and designate the winning lottery ticket as part of a chain. The player may enhance the prize associated with the first ticket in the chain by subsequent registration of an additional lottery ticket wherein, upon being registered, the additionally registered tickets in the chain may or may-not be individually redeemed.

Abstract: A method is provided for implementing a ticket-based Internet lottery game wherein winning plays of the Internet games are validated and redeemed through a lottery authority's existing validation and redemption system for on-line lottery tickets. Lottery tickets are provided for players, with the lottery tickets having a code that enables a player to access a designated web site and play an Internet game having a prize structure. The code is validated against a database and, for winning plays of the Internet game, a virtual bet is generated and transferred to the on-line lottery ticket validation system. Virtual drawings are periodically conducted within the on-line lottery ticket validation system in order to load win files corresponding to winning plays of the Internet game into the on-line lottery ticket winners database. The winning players are instructed as to a time after the virtual drawing when they can redeem their prize.

Abstract: A method and system for playing a terminal based lottery game having a slot machine theme includes assigning a defined set of objects to respective slot positions, the objects being unknown to game players. A player chooses at least one grouping of the slot positions from a plurality of possible groupings, and the system records the player's selection. For each of the slot positions, the system randomly selects an object from the set of objects assigned to each respective slot position such that a play set of the objects is generated for the player's grouping of slot positions. The player is awarded a prize amount that is a function of the number or combination of matches of objects within the player's play set. The methodology and system are particularly well suited for a poker slot machine theme game wherein the player's selected grouping corresponds to a poker hand, with the objects assigned to the respective slot positions corresponding to a poker deck of cards.