Patents by Inventor Amy J. Weiner

Amy J. Weiner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Hepatitis .delta. diagnostics and vaccines
    Patent number: 5389528
    Abstract: The entire genome of the hepatitis D virus has been shown to be a circular single-stranded RNA of 1679 bases. Several open reading frames in both the genomic and complementary strands indicate possible protein products. The products encoded in one open reading frame, ORF5, are identified as viral polypeptides p24.sup..delta. and p27.sup..delta., of which the nuclear .delta. antigens in HDV infected liver is comprised. These products, as well as others encoded in ORFs 1, 2, 6, and 7 are produced in recombinant expression systems. The ORF5 products, in particular, are useful for HDV diagnosis and vaccines.
    Type: Grant
    Filed: July 27, 1993
    Date of Patent: February 14, 1995
    Assignee: Chiron Corporation
    Inventors: Michael Houghton, Kang-Sheng Wang, Qui-Lim Choo, Amy J. Weiner, Lacy R. Overby
  • Hepatitis delta viral polypeptides
    Patent number: 5378814
    Abstract: The entire genome of the hepatitis D virus has been shown to be a circular single-stranded RNA of 1679 bases. Several open reading frames in both the genomic and complementary strands indicate possible protein products. The products encoded in one open reading frame. ORF5, are identified as vital polypeptides p24.sup..delta. and p27.sup..delta., of which the nuclear .delta. antigens in HDV infected liver is comprised. These products, as well as others encoded in ORFs 1, 2, 6, and 7 are produced in recombinant expression systems. The ORF5 products, in particular, are useful for HDV diagnosis and vaccines.
    Type: Grant
    Filed: July 9, 1992
    Date of Patent: January 3, 1995
    Assignee: Chiron Corporation
    Inventors: Michael Houghton, Kang-Sheng Wang, Qui-Lim Choo, Amy J. Weiner, Lacy R. Overby
  • Hepatitis C virus isolates
    Patent number: 5372928
    Abstract: Two new isolates of the Hepatitis C virus (HCV), J1 and J7, are disclosed. These new isolates comprise nucleotide and amino acid sequences which are distinct from the prototype HCV isolate, HCV1. Thus, J1 and J7 provide new polynucleotides and polypeptides for use, inter alia, in diagnostics, recombinant protein production and vaccine development.
    Type: Grant
    Filed: February 24, 1994
    Date of Patent: December 13, 1994
    Assignees: Chiron Corporation, The Director General of the National Institute of Health of Japan
    Inventors: Tatsuo Miyamura, Izumi Saito, Michael Houghton, Amy J. Weiner, Jang Han, Janice A. Kolberg, Tai-An Cha, Bruce D. Irvine