Patents by Inventor Amy Krutsick

Amy Krutsick has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • USE OF APOPTOTIC CELLS EX VIVO TO GENERATE REGULATORY T CELLS
    Publication number: 20210388318
    Abstract: Many cell types in the body can remove apoptotic and cellular debris from tissues; however, the professional phagocyte, or antigen presenting cell (“APC”), has a high capacity to do so. The recognition of apoptotic cells (“ACs”) occurs via a series of evolutionarily-conserved, AC associated molecular-pattern receptors (“ACAMPRs”) on APCs that recognize and bind corresponding apoptotic-cell-associated molecular patterns (“ACAMPs”). These receptors recognize ligands such as phosphotidyl serine and oxidized lipids found on apoptotic cells. Savill et al. (2002); and Gregory et al. (2004).
    Type: Application
    Filed: August 26, 2021
    Publication date: December 16, 2021
    Inventors: David Peritt, Kim Campbell, Amy Krutsick
  • Use of apoptotic cells ex vivo to generate regulatory T cells
    Patent number: 11124767
    Abstract: Many cell types in the body can remove apoptotic and cellular debris from tissues; however, the professional phagocyte, or antigen presenting cell (“APC”), has a high capacity to do so. The recognition of apoptotic cells (“ACs”) occurs via a series of evolutionarily-conserved, AC associated molecular-pattern receptors (“ACAMPRs”) on APCs that recognize and bind corresponding apoptotic-cell-associated molecular patterns (“ACAMPs”). These receptors recognize ligands such as phosphotidyl serine and oxidized lipids found on apoptotic cells. Savill et al. (2002); and Gregory et al. (2004).
    Type: Grant
    Filed: October 19, 2018
    Date of Patent: September 21, 2021
    Assignee: Mallinckrodt Pharmaceuticals Ireland Limited
    Inventors: David Peritt, Kim Campbell, Amy Krutsick
  • USE OF APOPTOTIC CELLS EX VIVO TO GENERATE REGULATORY T CELLS
    Publication number: 20190055516
    Abstract: Many cell types in the body can remove apoptotic and cellular debris from tissues; however, the professional phagocyte, or antigen presenting cell (“APC”), has a high capacity to do so. The recognition of apoptotic cells (“ACs”) occurs via a series of evolutionarily-conserved, AC associated molecular-pattern receptors (“ACAMPRs”) on APCs that recognize and bind corresponding apoptotic-cell-associated molecular patterns (“ACAMPs”). These receptors recognize ligands such as phosphotidyl serine and oxidized lipids found on apoptotic cells. Savill et al. (2002); and Gregory et al. (2004).
    Type: Application
    Filed: October 19, 2018
    Publication date: February 21, 2019
    Inventors: David Peritt, Kim Campbell, Amy Krutsick
  • Use of apoptotic cells ex vivo to generate regulatory T cells
    Patent number: 10138464
    Abstract: Many cell types in the body can remove apoptotic and cellular debris from tissues; however, the professional phagocyte, or antigen presenting cell (“APC”), has a high capacity to do so. The recognition of apoptotic cells (“ACs”) occurs via a series of evolutionarily-conserved, AC associated molecular-pattern receptors (“ACAMPRs”) on APCs that recognize and bind corresponding apoptotic-cell-associated molecular patterns (“ACAMPs”). These receptors recognize ligands such as phosphotidyl serine and oxidized lipids found on apoptotic cells. Savill et al. (2002); and Gregory et al. (2004).
    Type: Grant
    Filed: September 23, 2015
    Date of Patent: November 27, 2018
    Assignee: Mallinckrodt Hospital Products IP Limited
    Inventors: David Peritt, Kim Campbell, Amy Krutsick
  • Use of Apoptotic Cells Ex Vivo to Generate Regulatory T Cells
    Publication number: 20160046909
    Abstract: Many cell types in the body can remove apoptotic and cellular debris from tissues; however, the professional phagocyte, or antigen presenting cell (“APC”), has a high capacity to do so. The recognition of apoptotic cells (“ACs”) occurs via a series of evolutionarily-conserved, AC associated molecular-pattern receptors (“ACAMPRs”) on APCs that recognize and bind corresponding apoptotic-cell-associated molecular patterns (“ACAMPs”). These receptors recognize ligands such as phosphotidyl serine and oxidized lipids found on apoptotic cells. Savill et al. (2002); and Gregory et al. (2004).
    Type: Application
    Filed: September 23, 2015
    Publication date: February 18, 2016
    Inventors: David Peritt, Kim Campbell, Amy Krutsick
  • Use of apoptotic cells ex vivo to generate regulatory T cells
    Patent number: 9169461
    Abstract: Many cell types in the body can remove apoptotic and cellular debris from tissues; however, the professional phagocyte, or antigen presenting cell (“APC”), has a high capacity to do so. The recognition of apoptotic cells (“ACs”) occurs via a series of evolutionarily-conserved, AC associated molecular-pattern receptors (“ACAMPRs”) on APCs that recognize and bind corresponding apoptotic-cell-associated molecular patterns (“ACAMPs”). These receptors recognize ligands such as phosphotidyl serine and oxidized lipids found on apoptotic cells. Savill et al. (2002); and Gregory et al. (2004).
    Type: Grant
    Filed: November 2, 2006
    Date of Patent: October 27, 2015
    Assignee: Therakos, Inc.
    Inventors: David Peritt, Kim Campbell, Amy Krutsick
  • Use of Apoptotic Cells Ex Vivo to Generate Regulatory T Cells
    Publication number: 20080267934
    Abstract: Many cell types in the body can remove apoptotic and cellular debris from tissues; however, the professional phagocyte, or antigen presenting cell (“APC”), has a high capacity to do so. The recognition of apoptotic cells (“ACs”) occurs via a series of evolutionarily-conserved, AC associated molecular-pattern receptors (“ACAMPRs”) on APCs that recognize and bind corresponding apoptotic-cell-associated molecular patterns (“ACAMPs”). These receptors recognize ligands such as phosphotidyl serine and oxidized lipids found on apoptotic cells. Savill et al. (2002); and Gregory et al. (2004).
    Type: Application
    Filed: November 2, 2006
    Publication date: October 30, 2008
    Inventors: David Peritt, Kim Campbell, Amy Krutsick
  • Use of apoptotic cells ex vivo to generate regulatory T Cells
    Publication number: 20070098686
    Abstract: The present invention provides a method of generating T cells with regulatory activity by incubating leukocytes with autologous apoptotic peripheral blood mononuclear cells.
    Type: Application
    Filed: November 2, 2006
    Publication date: May 3, 2007
    Inventors: David Peritt, Kim Campbell, Amy Krutsick