Patents by Inventor Amy M. McCord

Amy M. McCord has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for producing high-fidelity autologous idiotype vaccines
    Patent number: 9725768
    Abstract: The present invention concerns methods for selecting and producing idiotype vaccines, and in particular methods for selecting and producing an idiotype vaccine for treatment of a B-cell derived malignancy in a subject based on the clonal profile (clonotype) of the malignancy; a method for producing an updated idiotype vaccine matched to a B-cell derived malignancy exhibiting a shifting clonal profile; and the high-fidelity idiotype vaccines produced using the methods. The invention also includes idiotype vaccines produced using the described methods and methods of treating B-cell derived malignancies using the produced vaccines.
    Type: Grant
    Filed: August 30, 2013
    Date of Patent: August 8, 2017
    Assignee: BIOVEST INTERNATIONAL, INC.
    Inventors: Carlos F. Santos, Amy M. Mccord, Mark Hirschel
  • METHODS FOR PRODUCING HIGH-FIDELITY AUTOLOGOUS IDIOTYPE VACCINES
    Publication number: 20150259749
    Abstract: The present invention concerns methods for selecting and producing idiotype vaccines, and in particular methods for selecting and producing an idiotype vaccine for treatment of a B-cell derived malignancy in a subject based on the clonal profile (clonotype) of the malignancy; a method for producing an updated idiotype vaccine matched to a B-cell derived malignancy exhibiting a shifting clonal profile; and the high-fidelity idiotype vaccines produced using the methods. The invention also includes idiotype vaccines produced using the described methods and methods of treating B-cell derived malignancies using the produced vaccines.
    Type: Application
    Filed: August 30, 2013
    Publication date: September 17, 2015
    Inventors: Carlos F. Santos, Amy M. Mccord, Mark Hirschel
  • MATERIALS AND METHODS FOR DIRECTING AN IMMUNE RESPONSE TO AN EPITOPE
    Publication number: 20140140986
    Abstract: The present invention relates to compositions, kits, and methods useful for directing an immune response to an epitope of an antigen in a subject, by sensitizing the subject to the epitope and/or by tolerizing the subject to the epitope. The sensitizing method comprises co-administering to the subject the epitope and an immunoglobulin M (IgM) constant region (IgM Fc region). The tolerizing method comprises co-administering to the subject the epitope and an immunoglobulin G (IgG) constant region (IgG Fc region) to the subject.
    Type: Application
    Filed: November 8, 2011
    Publication date: May 22, 2014
    Applicant: BIOVEST INTERNATIONAL, INC.
    Inventors: Carlos F. Santos, Mihaela Popa-Mckiver, Amy M. Mccord, Mark Hirschel
  • MATERIALS AND METHODS FOR DESIGNING AUTOLOGOUS IDIOTYPE VACCINES AND TREATMENT OF B-CELL MALIGNANCIES
    Publication number: 20140037615
    Abstract: The present invention relates to compositions, kits, and methods for preparing an autologous idiotype vaccine, or autologous anti-idiotype vaccine, for treatment of a B-cell malignancy based on the isotype(s) (class(es)) of immunoglobulins expressed by the malignancy; methods for treating B-cell malignancies; and methods for selecting a treatment for a subject having a B-cell malignancy.
    Type: Application
    Filed: August 12, 2011
    Publication date: February 6, 2014
    Applicant: BIOVEST INTERNATIONAL, INC.
    Inventors: Carlos F. Santos, Mihaela Popa-Mckiver, Amy M. McCord, Mark Hirschel