Patents by Inventor Amy M. Wen

Amy M. Wen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CANCER IMMUNOTHERAPY USING VIRUS PARTICLES
    Publication number: 20240024452
    Abstract: A method of treating cancer in a subject in need thereof includes administering in situ to the cancer a therapeutically effective amount of a virus or virus-like particle.
    Type: Application
    Filed: August 22, 2023
    Publication date: January 25, 2024
    Inventors: Nicole F. Steinmetz, Amy M. Wen, Steven Fiering, Patrick H. Lizotte
  • Cancer immunotherapy using virus particles
    Patent number: 11730803
    Abstract: A method of treating cancer in a subject in need thereof includes administering in situ to the cancer a therapeutically effective amount of a virus or virus-like particle.
    Type: Grant
    Filed: February 25, 2022
    Date of Patent: August 22, 2023
    Assignees: CASE WESTERN RESERVE UNIVERSITY, TRUSTEES OF DARTMOUTH COLLEGE
    Inventors: Nicole F. Steinmetz, Amy M. Wen, Steven Fiering, Patrick H. Lizotte
  • Cancer immunotherapy using virus particles
    Patent number: 11617787
    Abstract: A method of treating cancer in a subject that includes administering in situ to the cancer a therapeutically effective amount of a plant virus or virus-like particle to the subject.
    Type: Grant
    Filed: May 8, 2018
    Date of Patent: April 4, 2023
    Assignee: CASE WESTERN RESERVE UNIVERSITY
    Inventors: Nicole F. Steinmetz, Amy M. Wen, Steven Fiering, Patrick H. Lizotte
  • CANCER IMMUNOTHERAPY USING VIRUS PARTICLES
    Publication number: 20230024508
    Abstract: A method of treating cancer in a subject in need thereof includes administering in situ to the cancer a therapeutically effective amount of a virus or virus-like particle.
    Type: Application
    Filed: February 25, 2022
    Publication date: January 26, 2023
    Inventors: Nicole F. Steinmetz, Amy M. Wen, Steven Fiering, Patrick H. Lizotte
  • VIRAL NANOPARTICLE MULTIMERS
    Publication number: 20220090026
    Abstract: Virus particle multimers and methods of making and using such virus particle multimer are described. Virus particle multimers are constructed by preparing a plurality of asymmetrically functionalized virus particles bearing one or more functional groups and contacting the asymmetrically functionalized virus particles with a first linker molecule that reacts with the functional groups to form a virus particle multimer that includes a plurality of asymmetrically functionalized virus particles connected by the linker molecule. The asymmetrically functionalized virus particles are typically prepared by attaching the virus particles to a support surface to allow asymmetrical functionalization to be introduced.
    Type: Application
    Filed: December 7, 2021
    Publication date: March 24, 2022
    Inventors: Nicole F. Steinmetz, Amy M. Wen
  • Cancer immunotherapy using virus particles
    Patent number: 11260121
    Abstract: A method of treating cancer in a subject in need thereof includes administering in situ to the cancer a therapeutically effective amount of a virus or virus-like particle.
    Type: Grant
    Filed: April 17, 2020
    Date of Patent: March 1, 2022
    Assignee: CASE WESTERN RESERVE UNIVERSITY
    Inventors: Nicole F. Steinmetz, Amy M. Wen, Steven Fiering, Patrick H. Lizotte
  • Viral nanoparticle multimers
    Patent number: 11193111
    Abstract: Virus particle multimers and methods of making and using such virus particle multimer are described. Virus particle multimers are constructed by preparing a plurality of asymmetrically functionalized virus particles bearing one or more functional groups and contacting the asymmetrically functionalized virus particles with a first linker molecule that reacts with the functional groups to form a virus particle multimer that includes a plurality of asymmetrically functionalized virus particles connected by the linker molecule. The asymmetrically functionalized virus particles are typically prepared by attaching the virus particles to a support surface to allow asymmetrical functionalization to be introduced.
    Type: Grant
    Filed: December 27, 2013
    Date of Patent: December 7, 2021
    Assignee: CASE WESTERN RESERVE UNIVERSITY
    Inventors: Nicole F. Steinmetz, Amy M. Wen
  • CANCER IMMUNOTHERAPY USING VIRUS PARTICLES
    Publication number: 20210085777
    Abstract: A method of treating cancer in a subject that includes administering in situ to the cancer a therapeutically effective amount of a plant virus or virus-like particle to the subject.
    Type: Application
    Filed: May 8, 2018
    Publication date: March 25, 2021
    Inventors: Nicole F. Steinmetz, Amy M. Wen, Steven Fiering, Patrick H. Lizotte
  • CANCER IMMUNOTHERAPY USING VIRUS PARTICLES
    Publication number: 20210052717
    Abstract: A method of treating cancer in a subject in need thereof includes administering in situ to the cancer a therapeutically effective amount of a virus or virus-like particle.
    Type: Application
    Filed: April 17, 2020
    Publication date: February 25, 2021
    Inventors: Nicole F. Steinmetz, Amy M. Wen, Steven Fiering, Patrick H. Lizotte
  • Cancer immunotherapy using virus particles
    Patent number: 10639363
    Abstract: A method of treating cancer in a subject in need thereof includes administering in situ to the cancer a therapeutically effective amount of a virus or virus-like particle.
    Type: Grant
    Filed: May 8, 2017
    Date of Patent: May 5, 2020
    Assignee: CASE WESTERN REVERSE UNIVERSITY
    Inventors: Nicole F. Steinmetz, Amy M. Wen, Steven Fiering, Patrick H. Lizotte
  • MRP-14 targeting peptides and uses thereof
    Patent number: 10385321
    Abstract: A peptide for targeting MRP-14 has an amino acid sequence at least 80% identical to amino acid sequence selected from the group consisting of SEQ ID NO: 2, SEQ ID NO: 3, SEQ ID NO: 5, SEQ ID NO: 6, SEQ ID NO: 9, and SEQ ID NO: 10.
    Type: Grant
    Filed: June 6, 2017
    Date of Patent: August 20, 2019
    Assignee: CASE WESTERN RESERVE UNIVERSITY
    Inventors: Nicole F. Steinmetz, Amy M. Wen, Daniel Simon, Yunmei Wang
  • CANCER IMMUNOTHERAPY USING VIRUS PARTICLES
    Publication number: 20180133304
    Abstract: A method of treating cancer in a subject in need thereof includes administering in situ to the cancer a therapeutically effective amount of a virus or virus-like particle.
    Type: Application
    Filed: May 8, 2017
    Publication date: May 17, 2018
    Inventors: Nicole F. Steinmetz, Amy M. Wen, Steven Fiering, Patrick H. Lizotte
  • VIRAL NANOPARTICLE MULTIMERS
    Publication number: 20150361402
    Abstract: Virus particle multimers and methods of making and using such virus particle multimer are described. Virus particle multimers are constructed by preparing a plurality of asymmetrically functionalized virus particles bearing one or more functional groups and contacting the asymmetrically functionalized virus particles with a first linker molecule that reacts with the functional groups to form a virus particle multimer that includes a plurality of asymmetrically functionalized virus particles connected by the linker molecule. The asymmetrically functionalized virus particles are typically prepared by attaching the virus particles to a support surface to allow asymmetrical functionalization to be introduced.
    Type: Application
    Filed: December 27, 2013
    Publication date: December 17, 2015
    Inventors: Nicole F. Steinmetz, Amy M. Wen