Patents by Inventor Amy Madison Rhoden SMITH

Amy Madison Rhoden SMITH has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Polynucleotides, Compositions, and Methods for Genome Editing
    Publication number: 20240076636
    Abstract: Compositions and methods for gene editing. In some embodiments, a polynucleotide encoding Cas9 is provided that can provide one or more of improved editing efficiency, reduced immunogenicity, or other benefits.
    Type: Application
    Filed: April 7, 2023
    Publication date: March 7, 2024
    Applicant: Intellia Therapeutics, Inc.
    Inventors: Christian Dombrowski, Jonathan Douglas Finn, Amy Madison Rhoden Smith, Seth C. Alexander
  • Modified Guide RNAs
    Publication number: 20230287400
    Abstract: This disclosure relates to modified single and dual guide RNAs having improved in vitro and in vivo activity in gene editing methods.
    Type: Application
    Filed: September 1, 2022
    Publication date: September 14, 2023
    Applicant: Intellia Therapeutics, Inc.
    Inventors: Amy Madison Rhoden Smith, David V. Morrissey, Walter Strapps
  • Polynucleotides, compositions, and methods for genome editing
    Patent number: 11697806
    Abstract: Compositions and methods for gene editing. In some embodiments, a polynucleotide encoding Cas9 is provided that can provide one or more of improved editing efficiency, reduced immunogenicity, or other benefits.
    Type: Grant
    Filed: March 24, 2020
    Date of Patent: July 11, 2023
    Assignee: Intellia Therapeutics, Inc.
    Inventors: Christian Dombrowski, Jonathan Douglas Finn, Amy Madison Rhoden Smith, Seth C. Alexander
  • LIPID NANOPARTICLE FORMULATIONS FOR CRISPR/CAS COMPONENTS
    Publication number: 20230203480
    Abstract: The invention provides lipid nanoparticle-based compositions and methods useful for delivery of CRISPR/Cas gene editing components.
    Type: Application
    Filed: August 29, 2022
    Publication date: June 29, 2023
    Inventors: David V. Morrissey, Mihir Chandrakant Patel, Jonathan D. Finn, Amy Madison Rhoden Smith, Lucinda J. Shaw, Christian Dombrowksi, Ruchi Rudraprasad Shah
  • Modified guide RNAs
    Patent number: 11479767
    Abstract: This disclosure relates to modified single and dual guide RNAs having improved in vitro and in vivo activity in gene editing methods.
    Type: Grant
    Filed: June 7, 2019
    Date of Patent: October 25, 2022
    Assignee: Intellia Therapeutics, Inc.
    Inventors: Amy Madison Rhoden Smith, David V. Morrissey, Walter Strapps
  • Modified Guide RNAs for Gene Editing
    Publication number: 20210087568
    Abstract: This disclosure relates to modified guide RNAs having improved in vitro and in vivo activity in gene editing methods.
    Type: Application
    Filed: December 4, 2020
    Publication date: March 25, 2021
    Applicant: Intellia Therapeutics, Inc.
    Inventors: Amy Madison Rhoden Smith, Seth C. Alexander, Duncan Brown, Robert Brown, Adhiraj Lanba, Rebecca Lescarbeau, Reynald Michael Lescarbeau, Rubina Parmar, Matthew Roy, Paige Salerno, Jessica Lynn Seitzer
  • Polynucleotides, Compositions, and Methods for Genome Editing
    Publication number: 20200354702
    Abstract: Compositions and methods for gene editing. In some embodiments, a polynucleotide encoding Cas9 is provided that can provide one or more of improved editing efficiency, reduced immunogenicity, or other benefits.
    Type: Application
    Filed: March 24, 2020
    Publication date: November 12, 2020
    Applicant: Intellia Therapeutics, Inc.
    Inventors: Christian Dombrowski, Jonathan Douglas Finn, Amy Madison Rhoden Smith, Seth C. Alexander
  • Modified Guide RNAs
    Publication number: 20190316121
    Abstract: This disclosure relates to modified single and dual guide RNAs having improved in vitro and in vivo activity in gene editing methods.
    Type: Application
    Filed: June 7, 2019
    Publication date: October 17, 2019
    Applicant: Intellia Therapeutics, Inc.
    Inventors: Amy Madison Rhoden Smith, David V. Morrissey, Walter Strapps
  • LIPID NANOPARTICLE FORMULATIONS FOR CRISPR/CAS COMPONENTS
    Publication number: 20190136231
    Abstract: The invention provides lipid nanoparticle-based compositions and methods useful for delivery of CRISPR/Cas gene editing components.
    Type: Application
    Filed: March 30, 2017
    Publication date: May 9, 2019
    Inventors: David V. MORRISSEY, Mihir Chandrakant PATEL, Jonathan D. FINN, Amy Madison Rhoden SMITH, Lucinda J. SHAW, Christian DOMBROWSKI, Ruchi Rudraprasad SHAH