Patents by Inventor Amy Olson

Amy Olson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • OPTIMIZED TRANSGLUTAMINASE SITE-SPECIFIC ANTIBODY CONJUGATION
    Publication number: 20240131175
    Abstract: Provided herein are methods and compositions for site-specific conjugation of antibodies in the presence of a transglutaminase.
    Type: Application
    Filed: August 23, 2023
    Publication date: April 25, 2024
    Applicant: REGENERON PHARMACEUTICALS, INC.
    Inventors: Amy HAN, William OLSON, Christopher D'SOUZA
  • Bispecific antigen binding molecules that bind HER2, and methods of use thereof
    Patent number: 11958910
    Abstract: Provided herein are bispecific antigen-binding molecules that bind HER2 and methods of use thereof. The bispecific antigen-binding molecules comprise a first and a second antigen-binding domain, wherein the first and second antigen-binding domains bind to two different (preferably non-overlapping) epitopes of the extracellular domain of human HER2. The bispecific antigen-binding molecules cluster on the surface of HER2 IHC2+ and IHC3+ cells, and are internalized into the cellular lysosomes. Also included are antibody-drug conjugates (ADCs) comprising the antibodies or bispecific antigen-binding molecules provided herein linked to a cytotoxic agent, radionuclide, or other moiety, as well as methods of treating cancer in a subject by administering to the subject a bispecific antigen-binding molecule or an ADC thereof.
    Type: Grant
    Filed: February 26, 2021
    Date of Patent: April 16, 2024
    Assignee: Regeneron Pharmaceuticals, Inc.
    Inventors: Julian Andreev, Andres Perez Bay, Christopher Daly, Frank Delfino, Amy Han, Thomas Nittoli, William Olson, Gavin Thurston
  • STEROIDS AND PROTEIN-CONJUGATES THEREOF
    Publication number: 20240101594
    Abstract: Described herein are protein steroid conjugates that are useful, for example, for the target-specific delivery of glucocorticoids (GCs) to cells.
    Type: Application
    Filed: July 28, 2023
    Publication date: March 28, 2024
    Inventors: Amy HAN, Andrew J. MURPHY, William OLSON
  • MEDICAL PROCEDURE KIT AND ASSOCIATED METHODS
    Publication number: 20240081936
    Abstract: A medical procedure kit and related methods are provided. The medical procedure kit includes a tray defining a plurality of compartments, a medical waste basin removably supported within a first compartment of the plurality of compartments, and a plurality of medical procedure tools located within other compartments of the plurality of compartments. Additionally, the first compartment defines an access opening to manually engage the medical waste basin.
    Type: Application
    Filed: September 14, 2022
    Publication date: March 14, 2024
    Inventors: Kelly FitzPatrick Nace, Bernadette Cremin, Bethanie Szydlowski, Brianna Sarley, Amy Olson
  • Mutations in OAS1 genes
    Patent number: 9163222
    Abstract: Modified amino acid sequences of OAS1 proteins in non-human primates, and genes related thereto, are provided.
    Type: Grant
    Filed: November 14, 2012
    Date of Patent: October 20, 2015
    Assignee: Kineta Two, LLC
    Inventors: Shawn P Iadonato, Charles L Magness, P Campion Fellin, Christina A Scherer, Tory Hagen, Amy Olson
  • Mutations in OAS1 genes
    Patent number: 8951768
    Abstract: Modified amino acid sequences of OAS1 proteins in non-human primates, and genes related thereto, are provided.
    Type: Grant
    Filed: July 11, 2011
    Date of Patent: February 10, 2015
    Assignee: Kineta Two, LLC
    Inventors: Shawn P. Iadonato, Charles L. Magness, P. Campion Fellin, Christina A. Scherer, Tory Hagen, Amy Olson
  • Mutations on OAS1 Genes
    Publication number: 20120070424
    Abstract: Modified amino acid sequences of OAS1 proteins in non-human primates, and genes related thereto, are provided.
    Type: Application
    Filed: July 11, 2011
    Publication date: March 22, 2012
    Inventors: Shawn P. Iadonato, Charles L. Magness, P. Campion Fellin, Christina A. Scherer, Tory Hagen, Amy Olson
  • Mutations in OAS1 genes
    Patent number: 8030046
    Abstract: Modified amino acid sequences of OAS1 proteins in non-human primates, and genes related thereto, are provided.
    Type: Grant
    Filed: October 9, 2008
    Date of Patent: October 4, 2011
    Assignee: Kineta Two, LLC
    Inventors: Shawn P. Iadonato, Charles L. Magness, P. Campion Fellin, Christina A. Scherer, Tory Hagen, Amy Olson
  • MUTATIONS IN OAS1 GENES
    Publication number: 20090291074
    Abstract: Modified amino acid sequences of OAS1 proteins in non-human primates, and genes related thereto, are provided.
    Type: Application
    Filed: October 9, 2008
    Publication date: November 26, 2009
    Applicant: Illumigen Biosciences Inc.
    Inventors: Shawn P. IADONATO, Charles L. Magness, P. Campion Fellin, Christina A. Scherer, Tory Hagen, Amy Olson
  • Mutations in OAS1 genes
    Publication number: 20060275802
    Abstract: Modified amino acid sequences of OAS1 proteins in non-human primates, and genes related thereto, are provided.
    Type: Application
    Filed: May 3, 2006
    Publication date: December 7, 2006
    Inventors: Shawn Iadonato, Charles Magness, P. Fellin, Christina Scherer, Tory Hagen, Amy Olson