Patents by Inventor Amy P. N. Skubitz

Amy P. N. Skubitz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for treating conditions of the eye using polypeptides
    Patent number: 6013628
    Abstract: A method is provided for treating diseases and conditions of the eye which include scarring and proliferation of fibroblasts. The invention includes a method for treating proliferative vitreoretinopathy. The invention also includes a method for treating glaucoma. One embodiment of the method includes administering to the eye an amount effective for treating such a condition of a polypeptide. The polypeptide includes a sequence of at least about 5 amino acids corresponding substantially to an amino acid sequence from within the 33 kD fragment of the A chain of fibronectin, within the G domain of the A chain of laminin, or within the NC1 domain of the .alpha.2 chain of type IV collagen. Another embodiment of the method, which includes administering to the eye an amount of conjugate including the polypeptide and a carrier molecule conjugate, is also disclosed.
    Type: Grant
    Filed: February 27, 1995
    Date of Patent: January 11, 2000
    Assignee: Regents of the University of Minnesota
    Inventors: Amy P. N. Skubitz, Leo T. Furcht, Mark Balles, Dale S. Gregerson, Anita Agarwal, Martha M. Wright, Shobana Murali
  • Laminin a chain polypeptides from the amino terminal golbular domain
    Patent number: 5703205
    Abstract: Polypeptides derived from domain VI of the amino terminal globule of the A chain of laminin and having sequences of at least about 5 amino acids, and which exhibit cell adhesion and cell spreading capacity are described.Medical devices such as prosthetic implants, per-cutaneous devices and cell culture substrates coated with a composition including the described polypeptides are also provided.
    Type: Grant
    Filed: June 7, 1993
    Date of Patent: December 30, 1997
    Assignee: Regents of the University of Minnesota
    Inventors: Amy P. N. Skubitz, Leo T. Furcht
  • Laminin A chain polypeptides from the amino terminal globular domain
    Patent number: 5276136
    Abstract: Polypeptides derived from domain VI of the amino terminal globule of the A chain of laminin and having sequences of at least about 5 amino acids, and which exhibit cell adhesion and cell spreading capacity are described.Medical devices such as prosthetic implants, percutaneous devices and cell culture substrates coated wGOVERNMENT SUPPORTThis invention was made with government support under contract No. CA-29995 by the U.S. National Institutes of Health. The government has certain rights in the invention.
    Type: Grant
    Filed: June 8, 1992
    Date of Patent: January 4, 1994
    Assignee: Regents of the University of Minnesota
    Inventors: Amy P. N. Skubitz, Leo T. Furcht
  • Laminin a chain polypeptides from the carboxy terminal globular domain
    Patent number: 5266328
    Abstract: Polypeptides derived from the G domain of the A chain of laminin and having sequences of at least about 5 amino acids, and which exhibit heparin/glycosaminoglycan binding, cell adhesion and cell spreading capacity are described.Medical devices such as prosthetic implants, percutaneous devices and cell culture substrates coated with a composition including the described polypeptides are also provided.
    Type: Grant
    Filed: August 27, 1990
    Date of Patent: November 30, 1993
    Assignee: Regents of the University of Minnesota
    Inventors: Amy P. N. Skubitz, Leo T. Furcht