Patents by Inventor Amy RHODEN-SMITH

Amy RHODEN-SMITH has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11434486
    Abstract: The disclosure provides polynucleotides encoding a polypeptide including a morpholino linker. In some embodiments, the polynucleotides of the invention have increased stability compared to wild-type polynucleotides.
    Type: Grant
    Filed: September 19, 2016
    Date of Patent: September 6, 2022
    Assignee: ModernaTX, Inc.
    Inventors: Gabor Butora, Andrew W. Fraley, Edward John Miracco, Jennifer Nelson, Amy Rhoden Smith, Matthew Stanton
  • Patent number: 10407683
    Abstract: The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of circular polynucleotides.
    Type: Grant
    Filed: July 16, 2015
    Date of Patent: September 10, 2019
    Assignee: ModernaTX, Inc.
    Inventors: Jennifer Nelson, Andrew W. Fraley, Amy Rhoden Smith
  • Publication number: 20190078087
    Abstract: The disclosure provides polynucleotides encoding a polypeptide including a morpholino linker. In some embodiments, the polynucleotides of the invention have increased stability compared to wild-type polynucleotides.
    Type: Application
    Filed: September 19, 2016
    Publication date: March 14, 2019
    Inventors: Gabor BUTORA, Andrew W. FRALEY, Edward John MIRACCO, Jennifer NELSON, Amy RHODEN-SMITH, Matthew STANTON
  • Publication number: 20180256750
    Abstract: The invention features polynucleotides encoding a polypeptide including a 3?-stabilizing region and having increased stability compared to wild-type polynucleotides.
    Type: Application
    Filed: September 19, 2016
    Publication date: September 13, 2018
    Applicant: MODERNA THERAPEUTICS, INC.
    Inventors: Gabor BUTORA, Andrew W. FRALEY, Edward John MIRACCO, Jennifer NELSON, Amy RHODEN-SMITH, Matthew STANTON
  • Publication number: 20170204422
    Abstract: The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of circular polynucleotides.
    Type: Application
    Filed: July 16, 2015
    Publication date: July 20, 2017
    Inventors: Jennifer NELSON, Andrew W. FRALEY, Amy RHODEN-SMITH
  • Publication number: 20170204152
    Abstract: The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of chimeric polynucleotide molecules, which allow for customized placement, position and percent load of chemical modifications, which improve, alter or optimize certain physicochemical and pharmaceutical properties of the polynucleotides. In one non-limiting embodiment, such chimeric polynucleotides take the form or function as modified mRNA molecules which encode a polypeptide of interest. In one embodiment, such chimeric polynucleotides are substantially noncoding.
    Type: Application
    Filed: July 16, 2015
    Publication date: July 20, 2017
    Applicant: Moderna Therapeutics, Inc.
    Inventors: Jennifer NELSON, Andrew W. FRALEY, Amy RHODEN-SMITH