Patents by Inventor Amy Ripka

Amy Ripka has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 1,2-disubstituted heterocyclic compounds
    Patent number: 8466148
    Abstract: 1,2-disubstituted heterocyclic compounds which are inhibitors of phosphodiesterase 10 are described. Also described are processes, pharmaceutical compositions, pharmaceutical preparations and pharmaceutical use of the compounds in the treatment of mammals, including human(s) for central nervous system (CNS) disorders and other disorders which may affect CNS function. Among the disorders which may be treated are neurological, neurodegenerative and psychiatric disorders including, but not limited to, those associated with cognitive deficits or schizophrenic symptoms.
    Type: Grant
    Filed: November 7, 2011
    Date of Patent: June 18, 2013
    Assignee: EnVivo Pharmaceuticals, Inc.
    Inventors: Amy Ripka, Gideon Shapiro, Richard Chesworth
  • METHODS AND COMPOSITIONS FOR TREATING DISORDERS
    Publication number: 20130059869
    Abstract: Compounds and compositions for treating disorders related to TRPA1 are described herein.
    Type: Application
    Filed: February 22, 2012
    Publication date: March 7, 2013
    Inventors: Howard Ng, Manfred Weigele, Magdalene Moran, Jayhong Chong, Christopher Fanger, Glenn R. Larsen, Donato Del Camino, Neil Hayward, Steven P. Adams, Amy Ripka
  • Compounds for modulating TRPV3 function
    Patent number: 8389546
    Abstract: The present application relates to compounds and methods for treating pain and other conditions related to TRPV3.
    Type: Grant
    Filed: July 1, 2011
    Date of Patent: March 5, 2013
    Assignee: Hydra Biosciences, Inc.
    Inventors: Magdalene M. Moran, Jayhong A. Chong, Christopher Fanger, Amy Ripka, Glenn R. Larsen, Xiaoguang Zhen, Dennis John Underwood, Manfred Weigele
  • Phenoxymethyl heterocyclic compounds
    Patent number: 8343973
    Abstract: Phenoxymethyl compounds that inhibit at least one phosphodiesterase 10 are described as are pharmaceutical compositions containing such compounds an methods for treating various CNS disorders by administering such compounds to a patient in need thereof.
    Type: Grant
    Filed: December 18, 2009
    Date of Patent: January 1, 2013
    Assignee: EnVivo Pharmaceuticals, Inc.
    Inventors: Amy Ripka, Gideon Shapiro, Richard Chesworth
  • 1,2-Disubstituted Heterocyclic Compounds
    Publication number: 20120232265
    Abstract: 1,2-disubstituted heterocyclic compounds which are inhibitors of phosphodiesterase 10 are described. Also described are processes, pharmaceutical compositions, pharmaceutical preparations and pharmaceutical use of the compounds in the treatment of mammals, including human(s) for central nervous system (CNS) disorders and other disorders which may affect CNS function. Among the disorders which may be treated are neurological, neurodegenerative and psychiatric disorders including, but not limited to, those associated with cognitive deficits or schizophrenic symptoms.
    Type: Application
    Filed: November 7, 2011
    Publication date: September 13, 2012
    Inventors: Amy Ripka, Gideon Shapiro, Richard Chesworth
  • IMIDAZOTRIAZINONE COMPOUNDS
    Publication number: 20120157458
    Abstract: The present invention provides imidazotriazinone compounds which are inhibitors of phosphodiesterase 9. The present invention further provides processes, pharmaceutical compositions, pharmaceutical preparations and pharmaceutical use of the compounds in the treatment of PDE9 associated diseases or disorders in mammals, including humans.
    Type: Application
    Filed: September 20, 2011
    Publication date: June 21, 2012
    Inventors: Amy Ripka, Gideon Shapiro, Andrew J. McRiner
  • Methods and compositions for treating disorders
    Patent number: 8163761
    Abstract: Compounds and compositions for treating disorders related to TRPA1 are described herein.
    Type: Grant
    Filed: June 23, 2008
    Date of Patent: April 24, 2012
    Assignee: Hydra Biosciences, Inc.
    Inventors: Howard Ng, Manfred Weigele, Magdalene Moran, Jayhong Chong, Christopher Fanger, Glenn R. Larsen, Donato Del Camino, Neil Hayward, Steven P. Adams, Amy Ripka
  • Compounds for Modulating TRPV3 Function
    Publication number: 20120015979
    Abstract: The present application relates to compounds and methods for treating pain and other conditions related to TRPV3.
    Type: Application
    Filed: July 1, 2011
    Publication date: January 19, 2012
    Applicant: Hydra Biosciences, Inc,
    Inventors: Magdalene M. Moran, Jayhong A. Chong, Christopher Fanger, Amy Ripka, Glenn R. Larsen, Xiaoguang Zhen, Dennis John Underwood, Manfred Weigele
  • 1,2-disubstituted heterocyclic compounds
    Patent number: 8071595
    Abstract: 1,2-disubstituted heterocyclic compounds which are inhibitors of phosphodiesterase 10 are described. Also described are processes, pharmaceutical compositions, pharmaceutical preparations and pharmaceutical use of the compounds in the treatment of mammals, including human(s) for central nervous system (CNS) disorders and other disorders which may affect CNS function. Among the disorders which may be treated are neurological, neurodegenerative and psychiatric disorders including, but not limited to, those associated with cognitive deficits or schizophrenic symptoms.
    Type: Grant
    Filed: June 24, 2009
    Date of Patent: December 6, 2011
    Assignee: EnVivo Pharmaceuticals, Inc.
    Inventors: Amy Ripka, Gideon Shapiro, Richard Chesworth
  • DI-SUBSTITUTED PHENYL COMPOUNDS
    Publication number: 20110224204
    Abstract: Di-substituted phenyl compounds which are inhibitors of phosphodiesterase 10 are described as are processes, pharmaceutical compositions, pharmaceutical preparations and pharmaceutical use of the compounds in the treatment of mammals, including human(s) for central nervous system (CNS) disorders and other disorders which may affect CNS function. The disclosure also relates to methods for treating neurological, neurodegenerative and psychiatric disorders including but not limited to those comprising cognitive deficits or schizophrenic symptoms.
    Type: Application
    Filed: June 25, 2009
    Publication date: September 15, 2011
    Inventors: Richard Chesworth, Gideon Shapiro, Amy Ripka
  • Compounds for modulating TRPV3 function
    Patent number: 7998980
    Abstract: The present application relates to compounds and methods for treating pain and other conditions related to TRPV3.
    Type: Grant
    Filed: September 14, 2007
    Date of Patent: August 16, 2011
    Assignee: Hydra Biosciences, Inc.
    Inventors: Magdalene M. Moran, Jayhong A. Chong, Christopher Fanger, Amy Ripka, Glenn R. Larsen, Xiaoguang Zhen, Dennis John Underwood, Manfred Weigele
  • 5- AND 6-MEMBERED HETEROCYCLIC COMPOUNDS
    Publication number: 20110183976
    Abstract: 5- and 6-membered heterocyclic compounds which are inhibitors of phosphodiesterase 10 are described as are processes, pharmaceutical compositions, pharmaceutical preparations and pharmaceutical use of the compounds in the treatment of mammals, including human(s) for central nervous system (CNS) disorders and other disorders which may affect CNS function. Also described is the treatment of neurological, neurodegenerative and psychiatric disorders including but not limited to those comprising cognitive deficits or schizophrenic symptoms.
    Type: Application
    Filed: June 25, 2009
    Publication date: July 28, 2011
    Inventors: Amy Ripka, Gideon Shapiro, Richard Chesworth
  • PDE-10 INHIBITORS
    Publication number: 20110178083
    Abstract: Vicinal substituted cyclopropyl compounds which are inhibitors of phosphodiesterase 10 are described as are processes, pharmaceutical compositions, pharmaceutical preparations and pharmaceutical use of the compounds in the treatment of mammals, including human(s) for central nervous system (CNS) disorders and other disorders which may affect CNS function, for example neurological, neurodegenerative and psychiatric disorders including, but not limited to, those comprising cognitive deficits or schizophrenic symptoms.
    Type: Application
    Filed: July 9, 2009
    Publication date: July 21, 2011
    Inventors: Amy Ripka, Gideon Shapiro, Richard Chesworth
  • Compounds for Modulating TRPV3 Function
    Publication number: 20110151559
    Abstract: The present application relates to compounds and methods for treating pain and other conditions related to TRPV3.
    Type: Application
    Filed: March 4, 2011
    Publication date: June 23, 2011
    Applicant: Hydra Biosciences, Inc.
    Inventors: Jayhong A. Chong, Christopher Fanger, Glenn R. Larsen, Magdalene M. Moran, Howard Ng, Amy Ripka, Dennis John Underwood, Manfred Weigele, Xiaoguang Zhen
  • Compounds for Modulating TRPV3 Function
    Publication number: 20110144135
    Abstract: The present application relates to compounds and methods for treating pain and other conditions related to TRPV3.
    Type: Application
    Filed: February 7, 2011
    Publication date: June 16, 2011
    Applicant: Hydra Biosciences, Inc.
    Inventors: Jayhong A. Chong, Christopher Fanger, Glenn R. Larsen, William C. Lumma, JR., Anu Mahadevan, Peter Meltzer, Magdalene M. Moran, Amy Ripka, Dennis John Underwood, Manfred Weigele, Xiaoguang Zhen
  • Substituted quinazolin-4-one compounds for antagonizing TRPV3 function
    Patent number: 7893260
    Abstract: The present application relates to compounds and methods for treating pain and other conditions related to TRPV3. Suitable compounds include but are not limited to, for example, substituted quinazolin-4-ones of formula I.
    Type: Grant
    Filed: November 3, 2006
    Date of Patent: February 22, 2011
    Assignee: Hydra Biosciences, Inc.
    Inventors: Jayhong A. Chong, Christopher Fanger, Glenn R. Larsen, William C. Lumma, Jr., Magdalene M. Moran, Amy Ripka, Dennis John Underwood, Manfred Weigele, Xiaoguang Zhen
  • Phenoxymethyl Heterocyclic Compounds
    Publication number: 20100292238
    Abstract: Phenoxymethyl compounds that inhibit at least one phosphodiesterase 10 are described as are pharmaceutical compositions containing such compounds an methods for treating various CNS disorders by administering such compounds to a patient in need thereof.
    Type: Application
    Filed: December 18, 2009
    Publication date: November 18, 2010
    Inventors: Amy Ripka, Gideon Shapiro, Richard Chesworth
  • INHIBITION OF ALPHA-SYNUCLEIN TOXICITY
    Publication number: 20100273776
    Abstract: Compounds and compositions are provided for treatment or amelioration of one or more symptoms of ?-synuclein toxicity, ?-synuclein mediated diseases or diseases in which ?-synuclein fibrils are a symptom or cause of the disease.
    Type: Application
    Filed: March 29, 2007
    Publication date: October 28, 2010
    Applicants: FOLDRx PHARMACEUTICALS, INC, WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH
    Inventors: Susan L. Lindquist, Tiago Outeiro, Richard Labaudinière, James Fleming, Christine Ellen Bulawa, Charlotte Weigel, Feng Liang, Sandeep Gupta, Amy Ripka
  • Compounds for Modulating TRPV3 Function
    Publication number: 20100273777
    Abstract: The present application relates to compounds and methods for treating pain and other conditions related to TRPV3.
    Type: Application
    Filed: April 6, 2010
    Publication date: October 28, 2010
    Applicant: Hydra Biosciences, Inc.
    Inventors: Jayhong A. Chong, Christopher Fanger, Glenn R. Larsen, William C. Lumma, JR., Magdalene M. Moran, Amy Ripka, Dennis John Underwood, Manfred Weigele, Xiaoguang Zhen
  • Compounds for modulating TRPV3 function
    Patent number: 7803790
    Abstract: The present application relates to compounds and methods for treating pain and other conditions related to TRPV3.
    Type: Grant
    Filed: May 9, 2006
    Date of Patent: September 28, 2010
    Assignee: Hydra Biosciences, Inc.
    Inventors: Jayhong A. Chong, Christopher Fanger, Glenn R. Larsen, William C. Lumma, Jr., Anu Mahadevan, Peter Meltzer, Magdalene M. Moran, Amy Ripka, Dennis John Underwood, Manfred Weigele, Xiaoguang Zhen