Patents by Inventor Amy S. Espeseth

Amy S. Espeseth has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • HPV VACCINE
    Publication number: 20230270850
    Abstract: The present disclosure provides, among other things, a pharmaceutical composition that includes a lipid nanoparticle adjuvant and an anti-human papillomavirus (HPV) comprising HPV virus-like particles (VLPs) of at least one type of human papillomavirus (HPV) selected from the group consisting of HPV types: 6, 11, 16, 18, 26, 31, 33, 35, 39, 45, 51, 52, 53, 55, 56, 58, 59, 66, 68, 73, and 82.
    Type: Application
    Filed: March 10, 2023
    Publication date: August 31, 2023
    Applicant: Merck Sharp & Dohme LLC
    Inventors: Andrew J. Bett, John P. Bilello, Amy S. Espeseth, Tong-Ming Fu, Marian E. Gindy
  • HPV vaccine
    Patent number: 11638754
    Abstract: The present disclosure provides, among other things, a pharmaceutical composition that includes a lipid nanoparticle adjuvant and an anti-human papillomavirus (HPV) comprising HPV virus-like particles (VLPs) of at least one type of human papillomavirus (HPV) selected from the group consisting of HPV types: 6, 11, 16, 18, 26, 31, 33, 35, 39, 45, 51, 52, 53, 55, 56, 58, 59, 66, 68, 73, and 82.
    Type: Grant
    Filed: February 9, 2021
    Date of Patent: May 2, 2023
    Assignee: Merck Sharp & Dohme LLC
    Inventors: Andrew J. Bett, John P. Bilello, Amy S. Espeseth, Tong-Ming Fu, Marian E. Gindy
  • HPV VACCINE
    Publication number: 20230123584
    Abstract: The present disclosure provides, among other things, a pharmaceutical composition that includes a lipid nanoparticle adjuvant and an anti-human papillomavirus (HPV) comprising HPV virus-like particles (VLPs) of at least one type of human papillomavirus (HPV) selected from the group consisting of HPV types: 6, 11, 16, 18, 26, 31, 33, 35, 39, 45, 51, 52, 53, 55, 56, 58, 59, 66, 68, 73, and 82.
    Type: Application
    Filed: February 9, 2021
    Publication date: April 20, 2023
    Applicant: Merck Sharp & Dohme LLC
    Inventors: Marian E. Gindy, John P. Bilello, Amy S. Espeseth, Andrew J. Bett, Tong-Ming Fu
  • HPV VACCINE
    Publication number: 20230048144
    Abstract: The present disclosure provides, among other things, a single-dose vaccine composition that includes a chitosan adjuvant and HPV virus-like particles (VLPs) of at least one type of human papillomavirus (HPV) selected from the group consisting of HPV types: 6, 11, 16, 18, 26, 31, 33, 35, 39, 45, 51, 52, 53, 55, 56, 58, 59, 66, 68, 73, and 82, where the single-dose vaccine composition provides enhanced or comparable HPV vaccine response in comparison to a similar multiple-dose vaccine formulated without such chitosan adjuvant.
    Type: Application
    Filed: August 4, 2022
    Publication date: February 16, 2023
    Applicant: Merck Sharp & Dohme LLC
    Inventors: Andrew Bett, Colleen M. Barr, John P. Bilello, Pedro J. Cejas, Amy S. Espeseth, Tong-Ming Fu, Erica L. Strable, Sara Zimmermann
  • HPV VACCINE
    Publication number: 20210252138
    Abstract: The present disclosure provides, among other things, a pharmaceutical composition that includes a lipid nanoparticle adjuvant and an anti-human papillomavirus (HPV) comprising HPV virus-like particles (VLPs) of at least one type of human papillomavirus (HPV) selected from the group consisting of HPV types: 6, 11, 16, 18, 26, 31, 33, 35, 39, 45, 51, 52, 53, 55, 56, 58, 59, 66, 68, 73, and 82.
    Type: Application
    Filed: February 9, 2021
    Publication date: August 19, 2021
    Applicant: Merck Sharp & Dohme Corp.
    Inventors: Andrew J. Bett, John P. Bilello, Amy S. Espeseth, Tong-Ming Fu, Marian E. Gindy
  • NOVEL HIV TARGETS
    Publication number: 20110065087
    Abstract: A set of cellular genes that were identified by siRNA screening as being essential for Human Immunodeficiency Virus (HIV) infection. These genes are host cellular factors involved in DNA repair, specifically in the base excision repair pathway.
    Type: Application
    Filed: October 20, 2008
    Publication date: March 17, 2011
    Inventors: Amy S. Espeseth, Daria J. Hazuda, Min Xu, Honglin Zhou
  • Methods of Using SAHA for Treating HIV Infection
    Publication number: 20100324034
    Abstract: The present invention relates to pharmaceutical preparations and methods for treating individuals infected with the human immunodeficiency virus (HIV). The pharmaceutical preparations comprise SAHA and another anti-viral agent. The invention also relates to methods for treating HIV infected patients, particularly patients with persistent, latent HIV infection of CD4+ T cells, and thus make it possible to not just suppress but to eradicate the HIV infection.
    Type: Application
    Filed: February 8, 2008
    Publication date: December 23, 2010
    Inventors: Daria J. Hazuda, Amy S. Espeseth, David M. Margolis, Nancie M. Archin