Patents by Inventor Amy Shen FRIED
Amy Shen FRIED has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11867597Abstract: A method for making a plasmonic mushroom array includes: forming a plurality of metal nano-islands each having nanometer-range dimensions on a surface of a glass substrate; and subjecting to the glass substrate having the plurality of metal nano-islands formed thereon to reactive ion etching such that the plurality of metal nano-islands are converted to a plurality of mushroom-shaped structures each having a metal cap supported by a pillar made of a material of the glass substrate and each having dimensions smaller than the dimensions of the nano-islands, the plurality of mushroom-shaped structures being arranged in a substantially regular pattern with intervals smaller than average intervals between the nano-islands, thereby forming the plurality of nano-scale mushroom-shaped structures on the glass substrate that can exhibit localized surface plasmon resonance.Type: GrantFiled: February 22, 2022Date of Patent: January 9, 2024Assignee: OKINAWA INSTITUTE OF SCIENCE AND TECHNOLOGY SCHOOL CORPORATIONInventors: Nikhil Bhalla, Amy Shen Fried, Kang-Yu Chu
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Publication number: 20220170926Abstract: A method for making a plasmonic mushroom array includes: forming a plurality of metal nano-islands each having nanometer-range dimensions on a surface of a glass substrate; and subjecting to the glass substrate having the plurality of metal nano-islands formed thereon to reactive ion etching such that the plurality of metal nano-islands are converted to a plurality of mushroom-shaped structures each having a metal cap supported by a pillar made of a material of the glass substrate and each having dimensions smaller than the dimensions of the nano-islands, the plurality of mushroom-shaped structures being arranged in a substantially regular pattern with intervals smaller than average intervals between the nano-islands, thereby forming the plurality of nano-scale mushroom-shaped structures on the glass substrate that can exhibit localized surface plasmon resonance.Type: ApplicationFiled: February 22, 2022Publication date: June 2, 2022Applicant: OKINAWA INSTITUTE OF SCIENCE AND TECHNOLOGY SCHOOL CORPORATIONInventors: Nikhil Bhalla, Amy Shen Fried, Kang-Yu Chu
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Patent number: 11293920Abstract: A method for making a plasmonic mushroom array includes: forming a plurality of metal nano-islands each having nanometer-range dimensions on a surface of a glass substrate; and subjecting to the glass substrate having the plurality of metal nano-islands formed thereon to reactive ion etching such that the plurality of metal nano-islands are converted to a plurality of mushroom-shaped structures each having a metal cap supported by a pillar made of a material of the glass substrate and each having dimensions smaller than the dimensions of the nano-islands, the plurality of mushroom-shaped structures being arranged in a substantially regular pattern with intervals smaller than average intervals between the nano-islands, thereby forming the plurality of nano-scale mushroom-shaped structures on the glass substrate that can exhibit localized surface plasmon resonance.Type: GrantFiled: April 18, 2018Date of Patent: April 5, 2022Assignee: OKINAWA INSTITUTE OF SCIENCE AND TECHNOLOGY SCHOOL CORPORATIONInventors: Nikhil Bhalla, Amy Shen Fried, Kang-Yu Chu
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Publication number: 20210291159Abstract: An integrated system for sampling and processing a liquid suspension, the system comprising: a cartridge member comprising a sampling port on a first end of the cartridge member, a second one-way valve in communication with the sampling port, a stopper at a second end of the cartridge member, and a fluid chamber between the second one-way valve and the stopper; a body member having a first end configured to accept the first end of the cartridge member and a second end opposite the first end of the body member; and a cap unit disposed on the second end of the body member, the cap unit comprising a wash chamber, wherein the cap unit comprises a first one-way valve between the second end of the body member and the wash chamber and a filter between the first one-way valve and the wash chamber or a filter between the second end of the body member and the wash chamber and a first one-way valve between the filter and the wash chamber.Type: ApplicationFiled: May 18, 2018Publication date: September 23, 2021Inventors: Kazumi Toda-Peters, Amy Shen Fried, Shivani Sathish, Doojin Lee, Casey James Galvin, Kei Funakoshi
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Patent number: 11009440Abstract: A temperature-controllable microfluidic device includes: a microfluidic channel generally extending in a first direction for passing a specimen fluid; a microheater disposed along the microfluidic channel, the microheater being made of a resistive wire having a pair of serpentine-shaped portions generally extending in the first direction along respective sides of the microfluidic channel; and a temperature sensor disposed along the microfluidic channel, the temperature sensor being made of a resistive wire having a pair of serpentine-shaped portions generally extending in the first direction along the respective sides of the microfluidic channel.Type: GrantFiled: June 20, 2017Date of Patent: May 18, 2021Assignee: OKINAWA INSTITUTE OF SCIENCE AND TECHNOLOGY SCHOOL CORPORATIONInventors: Doojin Lee, Amy Shen Fried
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Publication number: 20210140954Abstract: A method for making a plasmonic mushroom array includes: forming a plurality of metal nano-islands each having nanometer-range dimensions on a surface of a glass substrate; and subjecting to the glass substrate having the plurality of metal nano-islands formed thereon to reactive ion etching such that the plurality of metal nano-islands are converted to a plurality of mushroom-shaped structures each having a metal cap supported by a pillar made of a material of the glass substrate and each having dimensions smaller than the dimensions of the nano-islands, the plurality of mushroom-shaped structures being arranged in a substantially regular pattern with intervals smaller than average intervals between the nano-islands, thereby forming the plurality of nano-scale mushroom-shaped structures on the glass substrate that can exhibit localized surface plasmon resonance.Type: ApplicationFiled: April 18, 2018Publication date: May 13, 2021Applicant: OKINAWA INSTITUTE OF SCIENCE AND TECHNOLOGY SCHOOL CORPORATIONInventors: Nikhil Bhalla, Amy Shen Fried, Kang-Yu Chu
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Publication number: 20210046476Abstract: It is an object of the present invention to achieve rapid surface patterning of biomolecules within microfluidic devices with high reproducibility. In this work, we present a new means of creating micro- and nano-patterns of aminosilanes within microfluidic devices via an aqueous based microcontact printing technique. To minimize the diffusion of molecules into the PDMS stamp, we use water as the inking solvent and enforce short incubation and contact times during the printing process to preserve the pre-defined resolution of patterned features. These patterns then serve as the building block to couple multiple biomolecules in solution onto a single surface for subsequent bioassays.Type: ApplicationFiled: September 2, 2020Publication date: February 18, 2021Inventors: Amy Shen FRIED, Sebastien Georg Gabriel RICOULT
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Patent number: 10851337Abstract: A disclosed insert for a circular-shaped petri dish can generate a substantially uniform electric field across the petri dish that is filled with a fluid establishing a salt bridge. The insert includes a circular-shaped bottom plate defining a circular-shaped space; a side channel vertically erecting from a circular periphery of said bottom plate; and a pair of current rectifying chambers each having a generally planar shape communicating with the side channel. In at least some aspects of the invention, portions of the side channel bridging the pair of current rectifying chambers each have a generally concave top profile having a lowest point at the center between the pair of current rectifying chambers such that, when the salt bridge is established, the circular-shaped space defined by the bottom plate exhibits a substantially uniform electric field in a substantially entire area of the space.Type: GrantFiled: September 16, 2016Date of Patent: December 1, 2020Assignee: OKINAWA INSTITUTE OF SCIENCE AND TECHNOLOGY SCHOOL CORPORATIONInventors: Hsieh-Fu Tsai, Amy Shen Fried, Ji-Yen Cheng
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Publication number: 20190187034Abstract: A temperature-controllable microfluidic device includes: a microfluidic channel generally extending in a first direction for passing a specimen fluid; a microheater disposed along the microfluidic channel, the microheater being made of a resistive wire having a pair of serpentine-shaped portions generally extending in the first direction along respective sides of the microfluidic channel; and a temperature sensor disposed along the microfluidic channel, the temperature sensor being made of a resistive wire having a pair of serpentine-shaped portions generally extending in the first direction along the respective sides of the microfluidic channel.Type: ApplicationFiled: June 20, 2017Publication date: June 20, 2019Applicant: OKINAWA INSTITUTE OF SCIENCE AND TECHNOLOGY SCHOOL CORPORATIONInventors: Doojin Lee, Amy Shen Fried
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Publication number: 20190030530Abstract: It is an object of the present invention to achieve rapid surface patterning of biomolecules within microfluidic devices with high reproducibility. In this work, we present a new means of creating micro- and nano-patterns of aminosilanes within microfluidic devices via an aqueous based microcontact printing technique. To minimize the diffusion of molecules into the PDMS stamp, we use water as the inking solvent and enforce short incubation and contact times during the printing process to preserve the predefined resolution of patterned features. These patterns then serve as the building block to couple multiple biomolecules in solution onto a single surface for subsequent bioassays.Type: ApplicationFiled: February 1, 2017Publication date: January 31, 2019Inventors: Amy Shen FRIED, Sebastien Georg Gabriel RICOULT
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Publication number: 20180251717Abstract: A disclosed insert for a circular-shaped petri dish can generate a substantially uniform electric field across the petri dish that is filled with a fluid establishing a salt bridge. The insert includes a circular-shaped bottom plate defining a circular-shaped space; a side channel vertically erecting from a circular periphery of said bottom plate; and a pair of current rectifying chambers each having a generally planar shape communicating with the side channel. In at least some aspects of the invention, portions of the side channel bridging the pair of current rectifying chambers each have a generally concave top profile having a lowest point at the center between the pair of current rectifying chambers such that, when the salt bridge is established, the circular-shaped space defined by the bottom plate exhibits a substantially uniform electric field in a substantially entire area of the space.Type: ApplicationFiled: September 16, 2016Publication date: September 6, 2018Applicant: OKINAWA INSTITUTE OF SCIENCE AND TECHNOLOGY SCHOOL CORPORATIONInventors: Hsieh-Fu TSAI, Amy Shen FRIED, Ji-Yen CHENG