Abstract: A multi-layered flexible sparger (100) that has a bottom film layer (102), a middle film layer (106), and a top film layer (110); a first inner mesh (104) disposed between the bottom film layer and the middle film layer; a second inner mesh (114) disposed between the middle film layer and the top film layer; and a port capable of delivering a gas to the multi-layered flexible sparger disposed between the top film layer and the bottom film layer, wherein the middle film layer comprises drill holes and the top film layer comprises drill holes.

Abstract: Methods and systems are disclosed for interactively developing an educational course and the materials for it using a backward design, or top-down, approach based on course objectives and course outcomes in one embodiment. Educators or other course creators are able to implement this design approach through an Integrated Design and Development Interface (IDDI). The IDDI guides course development by organizing course content in a relational database. The IDDI maps a plurality of course objectives to a plurality of course outcomes to create a course model. The IDDI uses the course model to generate and/or automatically user interfaces used by a course creator to input lower-level course information.

Abstract: This present invention relates to a pre-packaged set of disinfecting solution wipes used to prevent urinary tract and other infections, and reduce to bacterial growth. The wet wipes are stored in packages until needed, and are infused with a novel water and vinegar solution. The wipes can be applied multiple times a day to help eliminate odors, soothe skin, and reduce bacteria growth by neutralizing the pH of the user's skin. The wipes may also be used as a temporary bathing solution for those without immediate access to a shower or bathroom. The containers of the present invention are reusable, and feature a sealed lid to prevent the wet wipes from prematurely drying out.

Abstract: A multi-stage TFF apparatus, comprising a bioreactor capable of holding cell culture media; a first stage TFF device in fluid communication with the bioreactor; a storage tank in fluid communication with the first stage TFF device; a first recirculating loop in fluid communication with the first stage TFF device and the bioreactor; a second stage TFF device, in fluid communication with and downstream from the storage tank; and a second recirculating loop in fluid communication with the second stage TFF device and the storage tank.

Abstract: The present invention relates to the mesylate (CH3SO2?) salt of the following compound:

Abstract: A system for processing a biological fluid that includes a bioreactor, wherein the bioreactor includes a window, at least one port for allowing delivery of a processing aid; a control system, a sensor; a transmitter for transmitting the signal; a signal converter; a controller for receiving the signal; and a valve for delivering the processing aid to the port, wherein the sensor senses a process condition, transmits the signal, and the signal is compared with a reference signal and wherein a process action is optionally taken based on the comparison.

Abstract: This present invention relates to a pre-packaged set of disinfecting solution wipes used to prevent urinary tract and other infections, and reduce to bacterial growth. The wet wipes are stored in packages until needed, and are infused with a novel water and vinegar solution. The wipes can be applied multiple times a day to help eliminate odors, soothe skin, and reduce bacteria growth by neutralizing the pH of the user's skin. The wipes may also be used as a temporary bathing solution for those without immediate access to a shower or bathroom. The containers of the present invention are reusable, and feature a sealed lid to prevent the wet wipes from prematurely drying out.

Abstract: A collapsible container for a fluid that includes a flexible material, defining an internal working volume; at least one collapsible baffle adhered within the working volume of said collapsible container, the at least one baffle having one or more channels for delivering one or more fluids into the working volume via at least one hole in said one or more channels, one or more channels in said container for exiting or venting fluids from the working volume, and an impeller assembly disposed at least partially within said working volume of said container.

Abstract: Methods and systems are disclosed for interactively developing an educational course and the materials for it using a backward design, or top-down, approach based on course objectives and course outcomes in one embodiment. Educators or other course creators are able to implement this design approach through an Integrated Design and Development Interface (IDDI). The IDDI guides course development by organizing course content in a relational database. The IDDI maps a plurality of course objectives to a plurality of course outcomes to create a course model. The IDDI uses the course model to generate and/or automatically user interfaces used by a course creator to input lower-level course information.

Abstract: A container, such as a disposable or single use bioreactor, optionally having one or more inlets and one or more outlets and a mixer associated with the container to cause mixing, dispersing, homogenizing and/or circulation of one or more ingredients contained or added to the container. The container includes a flexible baffle shaped and positioned within the container to improve mixing, particularly to improve low shear mixing. The baffle is positioned within the container so as to disrupt the vortex formed by the mixer, or prevent formation of a vortex. The baffle is shaped with both horizontal and vertical elements to enhance disruption of the vortex across the entire vessel height and provide homogeneous mixing throughout all operating volumes. In certain embodiments, the baffle is X-shaped.

Abstract: An aeration device, and containers or vessels incorporating the same. The aeration device can comprise a plurality of interchangeable aeration elements that can produce gas bubble of different sizes and deliver them to the contents of the container. Also disclosed are containers, such as a disposable or single-use container, optionally having one or more inlets and one or more outlets, an aeration device including a plurality of aeration elements, and a mixer to cause mixing, dispersing, homogenizing and/or circulation of one or more ingredients contained or added to the container. The container can be a bioreactors and the aeration device controls the dissolved gas concentration content of the bioreactor contents, thereby facilitating proper growth of cell cultures in the bioreactor.

Abstract: A container, such as a disposable or single use bioreactor, optionally having one or more inlets and one or more outlets and a mixer associated with the container to cause mixing, dispersing, homogenizing and/or circulation of one or more ingredients contained or added to the container. The container includes a flexible baffle shaped and positioned within the container to improve mixing, particularly to improve low shear mixing. The baffle is positioned within the container so as to disrupt the vortex formed by the mixer, or prevent formation of a vortex. The baffle is shaped with both horizontal and vertical elements to enhance disruption of the vortex across the entire vessel height and provide homogeneous mixing throughout all operating volumes. In certain embodiments, the baffle is X-shaped.

Abstract: Methods and systems are disclosed for interactively developing an educational course and the materials for it using a backward design, or top-down, approach based on course objectives and course outcomes in one embodiment. Educators or other course creators are able to implement this design approach through an Integrated Design and Development Interface (IDDI). The IDDI guides course development by organizing course content in a relational database. The IDDI maps a plurality of course objectives to a plurality of course outcomes to create a course model. The IDDI uses the course model to generate and/or automatically user interfaces used by a course creator to input lower-level course information.