Abstract: Provided are methods for the preparation of certain substituted pyrrolidine compounds, forms of (2S,4R)-1-(2-aminoacetyl)-4-benzamidopyrrolidine-2-carboxylic acid hydrochloride, and methods for preparing and using these forms.

Abstract: A microfluidic apparatus can comprise a dielectrophoresis (DEP) configured section for holding a first liquid medium and selectively inducing net DEP forces in the first liquid medium. The microfluidic apparatus can also comprise an electrowetting (EW) configured section for holding a second liquid medium on an electrowetting surface and selectively changing a wetting property of the electrowetting surface. The DEP configured section can be utilized to select and move a micro-object in the first liquid medium. The EW configured section can be utilized to pull a droplet of the first liquid medium into the second liquid medium.

Abstract: A structure for providing a boundary for a chamber in a microfluidic apparatus can comprise dielectrophoresis (DEP) configurations each having an outer surface and electrowetting (EW) configurations each having an electrowetting surface. The DEP configurations can facilitate generating net DEP forces with respect to the outer surfaces of the DEP configurations to move micro-objects on the outer surfaces, and the EW configurations can facilitate changing wetting properties of the electrowetting surfaces to move droplets of liquid medium on the electrowetting surfaces.

Abstract: An integrated circuit device having memory is disclosed. The integrated circuit device comprises programmable resources; programmable interconnect elements coupled to the programmable resources, the programmable interconnect elements enabling a communication of signals with the programmable resources; a plurality of memory blocks; and dedicated interconnect elements coupled to the plurality of memory blocks, the dedicated interconnect elements enabling access to the plurality of memory blocks. A method of implementing memory in an integrated circuit device is also disclosed.

Abstract: The present invention provides an immunoconjugate having the formula: T-c-En-c-Fcn or T-c-Fcn-c-En; wherein, T is a single chain variable portion fragment of a monoclonal antibody (scFv) directed to a target protein, polypeptide, or fragment thereof, which is highly expressed on cancer cells; E is two or more foreign immunogenic CD8+ T cell antigenic epitopes; c is a peptide or polypeptide fragment thereof, capable of being cleaved by a specific protease; and Fc is two or more Fc portions of an IgG antibody. Nucleic acid sequences encoding the same and vectors containing said nucleic acid sequences are also provided. Methods of making the immunoconjugate, along with methods of making target cells susceptible to CTL mediated cell killing, and methods for treatment of cancers are also provided.

Abstract: Embodiments of the present invention address deficiencies of the art in respect to object attribution modification and provide a novel and non-obvious method, system and computer program product for drag and drop attributes for objects in a graphical user interface. In one embodiment of the invention, a method for drag and drop object attributes in a GUI can be provided. The method can include presenting draggable object attributes in the GUI, dragging one of the draggable object attributes into a separate target object in the GUI, and applying a value for the draggable object attribute to the separate target object. In one aspect of the embodiment, each of the draggable object attributes in the GUI can be separate and independent from any particular object in the GUI. In another aspect of the embodiment, each of the draggable object attributes in the GUI can be draggable from the particular object to a target object in the GUI.

Abstract: An outsole element for an article of footwear having a base and a lug that extends from the base. The outsole element includes a body and a cavity defined in the body. The cavity receives the lug to removably couple the body to the lug. Also, the cavity includes an internal undercut.

Abstract: An integrated circuit comprises a memory matrix including: a first memory cell array; a first multiplexer (MUX) coupled to an input of the first memory cell array; a second MUX coupled to an output of the first memory cell array; a second memory cell array; a third MUX coupled to an input of the second memory cell array; and a fourth MUX coupled to an output of the second memory cell array. The second MUX is coupled to the fourth MUX. The fourth MUX is configured to pass a selected one of: (1) an output from the third MUX, (2) an output from the second memory cell array, or (3) an output from the second MUX.

Abstract: A method, system and computer program product for retrieving both sensitive and non-sensitive content in a secure manner. After a proxy server establishes a secure connection between a client device and a web server, the client device receives the requested sensitive content, which includes an index file that contains a hash value that was generated by the web server. The web browser of the client device further issues a request to the proxy server to establish a non-secure connection to retrieve non-sensitive static content from the web server. After receiving the requested content, the web browser of the client device generates a hash value over the received content. If this generated hash value is equal to the hash value contained in the index file, then the web browser accepts the received non-sensitive static content. In this manner, both sensitive and non-sensitive content can be retrieved in a secure manner.

Abstract: A wear- and corrosion-resistant alloy, and related application method, where the alloy has by approximate weight %, C 0.12-0.7, Cr 20-30, Mo 7-15, Ni 1-4, and Co balance, wherein the alloy further contains one or more carbide-former elements from the group consisting of Ti, Zr, Hf, V, Nb, and Ta in a cumulative concentration to stoichiometrically offset between about 30% and about 90% of the C in the alloy.

Abstract: Embodiments of the invention provide an apparatus configured to form a material during an atomic layer deposition (ALD) process, such as a plasma-enhanced ALD (PE-ALD) process. In one embodiment, a plasma baffle assembly for receiving a process gas within a plasma-enhanced vapor deposition chamber is provided which includes a plasma baffle plate containing an upper surface to receive a process gas and a lower surface to emit the process gas, a plurality of openings configured to flow the process gas from above the upper surface to below the lower surface, wherein each opening is positioned at a predetermined angle of a vertical axis that is perpendicular to the lower surface, and a conical nose cone on the upper surface. In one example, the openings are slots positioned at a predetermined angle to emit the process gas with a circular flow pattern.

Abstract: A method of manufacturing solar cells is disclosed. The method comprises depositing an etch-resistant dopant material on a silicon substrate, the etch-resistant dopant material comprising a dopant source, forming a cross-linked matrix in the etch-resistant dopant material using a non-thermal cure of the etch-resistant dopant material, and heating the silicon substrate and the etch-resistant dopant material to a temperature sufficient to cause the dopant source to diffuse into the silicon substrate.

Abstract: Apparatus, method, and manufacture, illustratively the aggregation apparatus connects to a sites on the Internet, authenticates itself with the sites, and facilitates at least one of: retrieving user-selected information from the sites, parsing the user-selected information from the sites to produce an aggregation, and rendering at least some of the aggregation as the output; retrieving information from the sites, parsing the information from the sites, and user-selectedly filtering the parsed information in producing an aggregation of the parsed information in producing an aggregation, and rendering at least some of the aggregation as the output; and retrieving information from the sites, parsing the information from the sites, producing an aggregation of the parsed information so as to produce an aggregation of the parsed information, and user-selectedly rendering the aggregation as the output. The rendering can include supplying content from one of the sites to another of the sites.

Abstract: According to an embodiment disclosed herein, an apparatus for cooling a rotating part having cooling channels therein, the rotating part attaching to a disk rotating about an axis, the disk having a conduit for feeding a cooling fluid to the cooling channel is described. The apparatus has a first impeller rotating with the disk and in register with the conduit and an outer periphery of the disk, the impeller directing the cooling flow to the conduit.

Abstract: A computerized aggregation system including a computer, a display controlled by the computer, and networking hardware connecting the computer to a network, the computer programmed so that the aggregation apparatus: connects to at least one Internet-connected service; and authenticates itself with each said Internet-connected service; and retrieves input from said Internet-connected service; and connects to at least one appliance computer; and then authenticates itself with each said appliance computer; and retrieves input from each said appliance computer; and parses the input from each said Internet-connected service and parses the input from each said appliance computer so as to produce an aggregation of the parsed input; and renders the aggregation as output.

Abstract: The invention pertains to methods of using C?mX peptides (e.g., GLAGGSAQSQRAPDRVL; SEQ ID NO:2) that can bind effectively induce immune responses to membrane-bound IgE (mIgE) expressed on the surface of human B lymphocytes.