Abstract: Devices and techniques including process steps make use of recesses in conductive interconnect structures to form reliable low temperature metallic bonds. A fill layer is deposited into the recesses prior to bonding. First conductive interconnect structures are bonded at ambient temperatures to second metallic interconnect structures using direct bonding techniques, with the fill layers in the recesses in one or both of the first and second interconnect structures.

Abstract: The invention provides a chimeric antigen receptor (CAR) which can specifically bind to a BCMA protein comprising a BCMA binding structural domain, a transmembrane domain, a co-stimulatory domain, and an intracellular signaling domain. The invention also provides uses of the CAR in treating diseases or conditions linked to the expression of BCMA.

Abstract: Systems, computer-implemented methods, and non-transitory computer readable media are provided for sharing medical data. The disclosed systems may be configured to create a first workgroup having a first knowledgebase. This first knowledgebase may be federated with a common knowledgebase, and with a second knowledgebase of a second workgroup. At least one of the first knowledgebase, common knowledgebase, and second knowledgebase may be configured to store data items comprising associations, signs, and evidence. The signs may comprise measurements and contexts, and the associations may describe the relationships between the measurements and contexts. The evidence may support these associations. The disclosed systems may be configured to receive a request from a user in the first workgroup, retrieve matching data items, and optionally then output to the user at least some of the retrieved matching data items. The request may comprise at least one of a first association and a first measurement.

Abstract: The present invention relates to an endoscope system and an integrated design method for an endoscope camera optical system. The endoscope system comprises an object lens module, relay module, eye lens module, optical interface light path module and digital ultra-high definition camera successively arranged along the light path direction, wherein an image formed by the object lens module is projected to the optical interface light path module in a non-parallel light manner/divergent light manner after passing through the relay module and the eye lens module. According to the present invention, integrated ultra-high resolution of the optical endoscope and endoscope camera system is achieved by means of improving the resolution of the system.

Abstract: Embodiments of the present invention relate to the field of picture processing. Especially, the embodiments are directed to improving the deblocking filter of an image coding device. During the deblocking, at most a number MA of sample values of the first coding block adjacent to the block edge are modified and at most a number MB of sample values of the second coding block adjacent to the block edge are modified; or at most a number MA of sample values of the second coding block adjacent to the block edge are modified and at most a number MB of sample values of the first coding block adjacent to the block edge are modified, MA?MB.

Abstract: Embodiments of the present invention disclose a method for adding an authentication algorithm program, and a relevant device and system, where the method includes: receiving, by an SM-DP+ server, an authentication algorithm program sent by an MNO, where the authentication algorithm program corresponds to target information, and the target information is at least one of: firmware version information of an eUICC, an EID issuer identifier of the eUICC, platform/operating system version information of the eUICC, or capability information of the eUICC; and generating, by the SM-DP+ server, a bound profile package that includes the authentication algorithm program, and sending the bound profile package to the eUICC by using an LPA. As can be learned, the eUICC can add the authentication algorithm program into the eUICC in time by implementing the authentication algorithm program described in a first aspect.

Abstract: The filament bulb includes a bulb head, a bulb and multiple light source components. The bulb is disposed on the bulb head. The light source components are used for luminescence. The light source components are connected to the bulb head. The light source components are extended the bulb. The light source components include a central column, a bracket, and multiple LED light filaments. The central column is disposed on the bulb head. The bracket is disposed on the central column. The supporting wire is fixed on the central column. A circumferential direction of the central column is surrounded by multiple LED light filaments.

Abstract: An electrical energy generating device includes an electrical energy generating element, a first container, a second container, and a liquid having positive and negative ions. The electrical energy generating element includes a first porous electrode, an eggshell membrane, and a second porous electrode stacked on each other in that order. The first container is located on a side of the first porous electrode away from the eggshell membrane. The second container is located on a side of the second porous electrode away from the eggshell membrane. The liquid is located in at least one of the first container and the second container, and the liquid is configured to penetrate from one of the first container and the second container to another through the electrical energy generating element.

Abstract: The present invention discloses compounds of Formula (I), or pharmaceutically acceptable salts, thereof: which inhibit the protein(s) encoded by hepatitis B virus (HBV) or interfere with the function of the HBV life cycle of the hepatitis B virus and are also useful as antiviral agents. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from HBV infection. The invention also relates to methods of treating an HBV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention.

Abstract: The present disclosure provides a video coding method. The method includes obtaining an input video frame; obtaining, in response to a target processing method corresponding to the input video frame being a downsampling processing method, a sampling parameter corresponding to the input video frame, and determining downsampling information corresponding to the input video frame according to the sampling parameter, the sampling parameter being reproduced in a decoding process; and encoding the input video frame according to the downsampling information to obtain encoded data corresponding to the input video frame.

Abstract: A device may include a display portion that includes a display housing and a display at least partially within the display housing. The device may also include a base portion pivotally coupled to the display portion and including a bottom case, a top case coupled to the bottom case and defining an array of raised key regions, and a sensing system below the top case and configured to detect an input applied to a raised key region of the array of raised key regions.

Abstract: A method for generating electrical energy includes providing an electrical energy generating element. The electrical energy generating element includes a first porous electrode, an eggshell membrane, and a second porous electrode stacked on each other in that order. The electrical energy generating element has a first side and a second side opposite to the first side. A liquid having positive ions and negative ions is allowed to penetrate the electrical energy generating element from the first side to the second side.

Abstract: The present invention provides an all-ceramic joint bearing used in a high-temperature, corrosion and oxidation-prone environment, which mainly includes an inner ring and an outer ring which are made of zirconia, alumina or silicon carbide ceramic materials. The all-ceramic joint bearing is assembled into a whole through corresponding assembly technologies. An inner side of the outer ring is an inner arc surface, and the inner ring is an outer arc surface. A width of the inner ring is 3-5 mm greater than that of the outer ring, and a movable swing angle of the inner ring is 0-21°. The joint bearing made of the ceramic materials has an optimized structure by utilizing the ceramic material characteristics of high temperature resistance, corrosion resistance, high hardness, non-magnetic permeability, wear resistance and self-lubrication.

Abstract: A method for making an electrical energy generating element includes providing a first porous electrode, a second porous electrode, and an eggshell membrane. The first porous electrode, the eggshell membrane, and the second porous electrode are stacked on each other in that order. The present application also relates to an electrical energy generating device and a decorative ring.

Abstract: This disclosure provides a computer-implemented method. In this method, a payment confirmation message is received from a second device, the payment confirmation message being obtained by the second device from a payment server and including payment-related information and first identification information. The first identification information is identified from the payment confirmation message. Second identification information is obtained from the second device through short distance communication between the first device and the second device. It is determined whether the first identification information is consistent with the second identification information. In response to the first identification information being not consistent with the second identification information, a notification is provided on the first device.

Abstract: An anti-human PD-1 monoclonal antibody, and a preparation method therefor and an application thereof. The anti-human PD-1 monoclonal antibody has good bioactivity, can effectively bind with an extracellular region of a human PD-1 protein receptor, and can effectively seal PD-1 protein at protein level and cellular level and block the binding of the PD-1 protein with a ligand PD-L1, thereby effectively enhancing immunity. The monoclonal antibody can be applied independently or jointly with other antitumor drugs to tumor immunotherapy and the diagnosis and screening of patients with PD-L1 positive tumors; and the monoclonal antibody has a promising prospect in the preparation of drugs for treating tumors, resisting autoimmune diseases and the like.

Abstract: The present invention provides an ultra-microinjection detection and control device based on lensless imaging and a method thereof. A lensless optical liquid level sensor is used to measure a change of a liquid level in an injection needle. A microinjection control unit is used to track the change of the liquid level and correct an injection pressure of the injection pump. Transmitted light generated by a parallel light source passes through a transparent glass tube of the injection needle. Then the transmitted light passes through a light filtering film to reduce the intensity of the parallel light source to a photosensitivity range of a micro linear array image sensor chip. Finally, the transmitted light enters the micro linear array image sensor chip, so that the micro linear array image sensor chip measures the change of the liquid level in the injection needle.

Abstract: The present disclosure discloses an integrated weld position detection device based a binaural effect, including a microphone, a microphone holder, a megaphone, a conductive rod, and a current contact nozzle, where the microphone holder is provided with a first through hole in the center; the first through hole allows the conductive rod to pass through and is fixedly connected to the conductive rod; the current contact nozzle is fixedly connected to the conductive rod; the microphone holder is internally provided with two accommodating cavities; the two accommodating cavities are symmetrically distributed on left and right sides of the microphone holder; two microphones are respectively disposed inside the two accommodating cavities; the megaphone is provided with at least two sound transmission channels; first ends of the two sound transmission channels communicate with the two accommodating cavities respectively.

Abstract: A method of a base station (BS) for transmitting synchronization signals in a wireless communication system. The method comprises generating a primary synchronization signal (PSS) including one of multiple PSS sequences that is generated based on a M-sequence of length 127 in a frequency domain, wherein the PSS indicates part of cell identification (ID) information using a cyclic shift performed on the M-sequence generating the PSS; generating a secondary synchronization signal (SSS) including one of multiple SSS sequences that is generated based on multiple BPSK modulated M-sequences of length 127 in the frequency domain, wherein the SSS indicates the cell ID information using cyclic shifts performed on the M-sequences generating the SSS; and transmitting, to a user equipment (UE), the PSS and SSS over downlink channels.

Abstract: The present disclosure provides a backlight module and a display device. The backlight module includes a tight source layer, a light guiding layer and a dotted layer, a plurality of light emitting units is arranged on the light source layer; a plurality of reflective prism units is arranged on one side of the light guiding layer away from the light source layer, and positions of the plurality of reflective prism units are corresponding to the plurality of light emitting units respectively; the reflective prism unit is configured to reflect a light emitted by the light emitting unit into the light guiding layer and cause total reflection of the reflected light within the light guiding layer; and an optical structure for extracting light from the light guiding layer is provided with the dotted layer.