Abstract: The present disclosure relates to the field of bioengineering and pharmaceutical and chemical production. In particular, provided is a polynucleotide comprising a coding sequence of toluene dioxygenase. Also provided are an expression cassette, a vector and a host cell comprising the polynucleotide, as well as use thereof in the preparation of cis-cyclohexadiene o-diol compounds.

Abstract: This invention discloses a method and system for the segmentation and clustering of nuclei based on single-cell pathological images. The contour tracing method is used to calculate all the closed contours existing in the pathological tissue images; and optimizes the contours to obtain the segmented images of the nuclei. Then, according to the mask image corresponding to the segmented images of the nuclei, the segmented images of the nuclei are divided into individual nucleus images; the influencing features of the nuclei in the corresponding area are extracted through the mask image; through feature selection, redundant features are removed, and then the UMAP feature reduction method is used to select the two most important features for clustering the nuclei. By first segmenting and dividing the nucleus area in the pathological images, and then using the divided single nucleus for feature extraction, the basis for clustering is made more objective.

Abstract: The present invention relates to an authentication information manager computer program product, which is executed by a processing unit. The computer program product includes: a physical private key acquisition module configured to receive an identity information to form an initialization authentication information including a part of the identity information; an authentication information management module configured to record a first set of authentication information for logging into a first networking application; and a multiparty multifactor dynamic strong encryption authentication transmission module configured to implement a multiparty multifactor dynamic digital authentication method with strong encryption to transmit the transfigurated initialization authentication information to a network application serving device including an authentication information manager back end and a third-party security serving equipment to be verified.

Abstract: Presented herein are techniques for identifying and/or validating sequence variants in genomic sequence data. The techniques include generating an error rate reflective of sequence errors present in the genomic sequence data. The error rate may be used to validate potential sequence variants. The error rate may be based on errors identified during consensus sequence confirmation for sequence reads associated with individual unique molecular identifiers.

Abstract: A semiconductor device includes a gate structure on a substrate, a first spacer on a sidewall of the gate structure, a second spacer on a sidewall of the first spacer, a third spacer on a sidewall of the second spacer, and first and second stacks of an epitaxial layer and a cap layer respectively disposed at first and second sides of the gate structure. Preferably, a part of the second spacer comprises an I-shape, the cap layer includes a planar top surface and an inclined sidewall, the cap layer contacts the second spacer and the third spacer directly, and the cap layer includes a vertical sidewall connected to the inclined sidewall.

Abstract: A new pharmaceutical use of potassium ATP channel modulator, namely potassium ATP channel modulator (such as diazoxide, cromakalim, pinacidil, nicorandil, and aprikalim, etc.) in preparation of antidiabetic nephropathy drugs, is provided. Also provided with a potassium ATP channel modulator as an active ingredient of the pharmaceutical composition is used for the prevention or treatment of diabetic nephropathy. A diabetic rat model created by streptozotocin (STZ) is used and a diabetic nephropathy model with a high-fat diet in rats is generated. Urine microalbumin (mALB) is used as an indicator to test whether the rat enters diabetic nephropathy. In addition, rat body weight and its blood glucose level are used as an indicator to decide whether the model is successful. The experimental results showed that the administration of potassium ATP channel openers such as diazoxide to diabetic rats could delay the process of kidney injury in diabetic rats.

Abstract: A disinfection cap is described for connection to a medical connector; the disinfection cap includes a housing having a top wall and sidewall forming a cavity. In one or more embodiments, a retention rod forming a fluid reservoir is disposed within the cavity for retaining disinfectant. In one or more embodiments, a corrugated capsule is disposed within the cavity for retaining disinfectant. Pressure buildup within the cavity due to insertion of a luer connector causes expulsion of disinfectant, thereby disinfecting the luer connector.

Abstract: A signal transfer method for communication, radar sensing, or a combination thereof, includes: transmitting, from a UE, a capability message indicating a capability of the UE to perform antenna switching for radar signal transmission and for communication signal transmission; receiving, at the UE from a network entity, a configuration message indicating a radar signal transmission configuration, or a communication signal transmission configuration, or a combination thereof; and transmitting, from the UE, one or more outbound signals, the one or more outbound signals comprising a radar signal in accordance with the radar signal transmission configuration, or comprising a communication signal in accordance with the communication signal transmission configuration, or a combination thereof.

Abstract: The present disclosure relates to a computing device, and related products. The product includes a control unit. The control unit includes an instruction caching unit, an instruction processing unit and a storage queue unit. The instruction caching unit is used for storing a calculation instruction associated with an artificial neural network operation; the instruction processing unit is used for analyzing the calculation instruction to obtain a plurality of operation instructions; and the storage queue unit is used for storing an instruction queue, where the instruction queue includes a plurality of operation instructions or calculation instructions to be executed in the order of the queue. By using the computing device and related products, the present disclosure may improve the operation efficiency of the related products when performing neural network model operations.

Abstract: The invention relates to compositions and methods for targeting polynucleotides with eukaryotic RNA-guided nucleases. In particular, programmable RNA-guided DNA endonucleases termed Fanzors, can be harnessed for genome editing.

Abstract: The invention relates to a multi-source wireless optical communication spectrum sensing system, including: a transmit end, configured to transmit an optical signal, the transmit end including multiple LEDs; and a secondary user terminal, configured to: receive the optical signal transmitted by the transmit end, convert the optical signal into an electrical signal, filter out a direct current component in the electrical signal to obtain a filtered electrical signal, sample the electrical signal to obtain sampling data and a corresponding sampling quantity, perform channel estimation based on the sampling quantity and acquired location data of the secondary user terminal to obtain a channel matrix, calculate a detection metric M and a decision threshold K based on the channel matrix, the sampling data, and the sampling quantity, and determine, based on a value relationship between M and K, whether a channel is occupied by a primary user.

Abstract: A method of producing glass includes discharging an outflow (22, 1022) of fined molten glass from a fining tank (18, 1018) of a vacuum induction fining apparatus (10, 1010) and delivering the fined molten glass into a thermal conditioning tank (16, 1016) that is separated from the fining tank by an open space (26, 1026) occupied by an ambient environment (24, 1024). The fining tank includes a vertically-elongated housing (80, 1080) that defines an interior fining chamber (82, 1082) where a bath (76, 1076) of molten glass is collected and maintained. The interior fining chamber is maintained at subatmospheric pressure and the housing is surrounded by at least one induction coil (74, 1074) to introduce heat into the molten glass bath. The vacuum maintained in the interior fining chamber and the heating supplied by the induction coil(s) promote the ascension of gas bubbles upwards through the molten glass bath. A glass-producing system that includes the vacuum induction fining apparatus is also disclosed.

Abstract: Provided is a method for preparing a cobalt-free positive electrode material, the method comprising the following steps: (1) mixing lithium titanate and a metal source, carrying out a primary sintering treatment, adding a carbon source, and carrying out a secondary sintering treatment to obtain a carbon-coated, metal-doped lithium titanate additive; (2) mixing a lithium source with a cobalt-free precursor, and performing a high-temperature treatment to obtain a substrate material; and (3) mixing the carbon-coated, metal-doped lithium titanate additive with the substrate material, and then performing a heat treatment to obtain a cobalt-free positive electrode material. Further provided are a cobalt-free positive electrode material prepared by means of the preparation method, a positive electrode sheet including the positive electrode material, and a lithium-ion battery including the positive electrode sheet.

Abstract: Disclosed are a data transmission method and device, and a storage medium. The method may include: preconfiguring a channel state information (CSI) reporting policy and an information field of downlink control information (DCI), the CSI reporting policy includes a second communication node reporting one piece of CSI associated with a Multi Transmission Receiving Point (MTRP) and X pieces of CSI associated with a Single Transmission Receiving Point (STRP), and the information field of the DCI includes a first bit used for indicating a CSI sharing status, X includes 0, 1, and 2; and sending the CSI reporting policy and the DCI to the second communication node, such that the second communication node performs CSI reporting according to the CSI reporting policy and performs CSI sharing according to the information field of the DCI.

Abstract: An electronic device (such as an access point) is described. This electronic device transmits an orthogonal frequency division multiple access (OFDMA) frame to a recipient electronic device (such as a client or a station). The OFDMA frame includes multiple predefined resource units (RUs) allocated to the recipient electronic device in a set of predefined RUs having associated frequency bandwidths. Moreover, the multiple predefined RUs include two or more first predefined RUs having a first number of tones less than a predefined amount, or two or more second predefined RUs having a second number of tones greater than or equal to the predefined amount. For example, the predefined amount may include 242 tones. Note that the multiple predefined RUs may have the same or different numbers of tones. Moreover, the electronic may receive an acknowledgment or a block acknowledgment from the recipient electronic device.

Abstract: Automatic process generation and recommendation can include extracting, in real time, features from user input to a computer. The features extracted can be compared with recorded features corresponding to a prior behavior. A user-intended action can be predicted in response to a match between the features extracted and the features corresponding to the prior behavior. A sequence of processor-executable actions corresponding to the prior behavior can be generated.

Abstract: The linkage dual mode release includes a main body, a string hook, a linkage lock, a thumb trigger, a sear, and a trigger bar flange. The main body has a first finger groove arm. The string hook is elastically pivoted to one end of the main body for releasably hook to a bow string. The linkage lock is elastically pivoted to an outer surface of the main body, and the linkage lock is located adjacent the other end of the main body opposite to the string hook. The linkage lock has a locking arm and a lever arm extending to the main body. The thumb trigger is mounted to the linkage lock extending away from the main body. The sear is pivoted to the main body, a rest member is located between the sear and the main body, the sear comprises a second finger groove arm.

Abstract: Disclosed herein is an example track pad having a ground-contacting portion for use in a track-based machine to propel and support the machine across a supporting surface. The track pad may be a track pad that forms a link of a chain forming the track for the track-based machine. The track pad includes a cast body formed of a first alloy steel having a first strength and toughness. The track pad includes a roll path that contacts a roller of the track-based machine. The roll path is hardened through an induction hardening process to achieve a hardness level at a depth of 32 millimeters or more from the surface of the roll path. The roll path is shaped and positioned to contact rollers of the track drive assembly and thereby reduce wear and fatigue on the track pad as a result of contact and force transferred through the roller.

Abstract: Disclosed is a pixel circuit including a drive sub-circuit, a writing sub-circuit, a reset sub-circuit, a coupling sub-circuit, a storage sub-circuit, and a light emitting element, wherein the drive sub-circuit is configured to provide a drive current to the light emitting element under control of signals of a first node and a second node; the writing sub-circuit is configured to write a signal of a data signal terminal to the second node under control of a signal of a scan signal terminal; the coupling sub-circuit is configured to raise the voltage of the first node through a coupling action; the reset sub-circuit is configured to reset an anode terminal of the light emitting element under control of a signal of the scan signal terminal and reset a control terminal of the drive sub-circuit under control of a signal of a reset control signal terminal.

Abstract: A battery cell includes an electrode stack including a pair of an anode and a cathode and a separator. Operation of the battery cell causes gas or moisture to form. The battery cell further includes a stiff frame. The frame includes a hollow portion. The electrode stack is disposed within the hollow portion. The frame includes a portion of the frame that is porous or includes a gas diffusion membrane. The battery cell further includes an electrolyte disposed within the frame and in contact with the electrode stack and a functional material disposed within the battery cell and outside of the hollow portion. The functional material absorbs the gas/moisture. The portion of the frame that is porous or includes a gas diffusion membrane enables the gas/moisture to exit the hollow portion and come into contact with the functional material while maintaining the electrolyte within the frame.