Abstract: The present invention pertains to pharmaceutical chemical field, and relates to a sterol derivative as well as preparation method and uses thereof. Specifically, the present invention relates to a compound of Formula I, or a pharmaceutically acceptable salt, ester or ether thereof, wherein, R1 is selected from the group consisting of —OH, ?O(carbonyl), H, and C1-C3 alkyl; R2 is selected from the group consisting of —OH, H, and C1-C3 alkyl; R3 is selected from the group consisting of —OH, ?O, H, and C1-C3 alkyl; R4 is selected from the group consisting of —OH, H, and C1-C3 alkyl; and none, one, two, three or four of R1, R2, R3, and R4 are —OH. The compound of the present invention can inhibit HMG-CoA reductase, tumor cells and lipase effectively, and is a potential drug for reducing blood-fat, antitumors, or for losing weight.

Abstract: An antenna apparatus and an electronic device, the antenna apparatus comprising: a near-field communication chip for providing a differential excitation current; a first non-near-field communication chip for providing a first non-near-field communication excitation signal; a grounding plane on which a conductive path is formed; a first conductor structure, comprising a first conductor section and a second conductor section spaced apart from each other; and a second conductor structure.

Abstract: A core sampling and preservation system comprises the following sequentially connected modules: a drive module (300), a preservation module (200) and a core sampling module (100). The core sampling module (100) comprises a core drilling tool and a core sample storage compartment. The preservation module (200) comprises a core sample preservation container. The drive module comprises a core drill having a liquid channel. The core sample preservation container comprises an inner core barrel (28), an outer core barrel (26) and an energy storage device (229). The outer core barrel (26) is sleeved onto the inner core barrel (28). An upper end of the inner core barrel (28) is in communication with a liquid nitrogen storage tank (225). The liquid nitrogen storage tank (225) is positioned inside the outer core barrel (26). The energy storage device (229) is in communication with the outer core barrel (26). The outer core barrel (26) is provided with a butterfly valve (23).

Abstract: The present disclosure provides a video data processing method for cross-component sample adaptive offset (CCSAO). The method includes determining an index based on a vertical coordinate of a chroma sample within a picture; determining a luma sample based on the index; classifying the chroma sample based on a reconstructed value associated with the luma sample; determining an offset based on the classification; and adding the offset to a reconstructed value associated with the chroma sample.

Abstract: Various aspects of the present disclosure generally relate to wireless communication. In some aspects, a repeater may transmit, via a first interface, information associated with a capability of the repeater to provide a wideband signal on a second interface. The repeater may receive via the first interface, a configuration for transmitting the wideband signal on the second interface, and may transmit the wideband signal on the second interface based at least in part on the configuration. Numerous other aspects are provided.

Abstract: Embodiments are directed to a method for accelerating machine learning using a plurality of graphics processing units (GPUs), involving receiving data for a graph to generate a plurality of random samples, and distributing the random samples across a plurality of GPUs. The method may comprise determining a plurality of communities from the random samples using unsupervised learning performed by each GPU. A plurality of sample groups may be generated from the communities and may be distributed across the GPUs, wherein each GPU merges communities in each sample group by converging to an optimal degree of similarity. In addition, the method may also comprise generating from the merged communities a plurality of subgraphs, dividing each sub-graph into a plurality of overlapping clusters, distributing the plurality of overlapping clusters across the plurality of GPUs, and scoring each cluster in the plurality of overlapping clusters to train an AI model.

Abstract: A method for assembling an optical lens includes preparing a first lenses part including a first lens and a second lenses part including a second lens, capturing the first lenses part, and adjusting a posture of the first lenses part according to a distance measurement result, so that an included angle between a first end surface of the first lenses part and a second end surface of the second lenses part is less than a threshold of inclination angle. The method also includes adjusting the first lenses part at degree of freedom of linear movement to complete pre-positioning, performing an active alignment of a position of the first lenses part at the degree of freedom of linear movement according to an actual imaging result, and fixing the first and second lenses parts together, so that their relative positions are maintained at the relative positions determined by the active alignment.

Abstract: The present invention discloses a method for cleaning substrate without damaging patterned structure on the substrate using ultra/mega sonic device, comprising: applying liquid into a space between a substrate and an ultra/mega sonic device; setting an ultra/mega sonic power supply at frequency f1 and power P1 to drive said ultra/mega sonic device; after micro jet generated by bubble implosion and before said micro jet generated by bubble implosion damaging patterned structure on the substrate, setting said ultra/mega sonic power supply at frequency f2 and power P2 to drive said ultra/mega sonic device; after temperature inside bubble cooling down to a set temperature, setting said ultra/mega sonic power supply at frequency f1 and power P1 again; repeating above steps till the substrate being cleaned.

Abstract: Methods and apparatus relate to the synthesis of polynucleotides having a predefined sequence on a support. Assembly methods include primer extension to generate overlapping construction oligonucleotides and assembly of the polynucleotides of interest onto an anchor support-bound oligonucleotides. Methods and apparatus for selection of polynucleotides having the predefined sequence and/or length are disclosed.

Abstract: A plurality of pixel drive circuits form part of an array of emissive elements. The plurality of pixel drive circuits are disposed to form a plurality of rows and a plurality of columns. The plurality of pixel drive circuits are organized into sets of pixel drive circuits, and each set comprises at least one pixel drive circuit. A FET of a set of pixel drive circuits shares a common well with other FETs of similar function in the same set of pixel drive circuits positioned therein, such that the variance of the threshold voltages of those FETs is substantially reduced. Each of the pixel drive circuits comprises a circuit operative to deliver a current at a predetermined voltage to an emissive device and a memory circuit operative to receive modulation data and to use same to modulate the current output of the pixel drive circuit.

Abstract: The present invention provides a photodiode and a display screen. The photodiode includes a first electrode and a second electrode in order. When a direction of an incident light of the photodiode is a first direction, a material of the first electrode is a transparent conductive material, and a material of the second electrode is a metal material. When the direction of the incident light of the photodiode is a second direction, the second electrode is made of a transparent conductive material, and the first electrode is made of a metal material.

Abstract: A manufacturing method of a semiconductor device includes: providing a semiconductor stack layer, wherein the semiconductor stack layer includes a first type semiconductor layer, a quantum well layer, and a second type semiconductor layer stacked in sequence; growing an aluminum nitride layer on the second type semiconductor layer; and annealing the aluminum nitride layer to achieve quantum well intermixing.

Abstract: Disclosed is a method for purifying sucralose, including: removing a solvent from a sucralose reaction solution to obtain a concentrated crude sucralose solution; under stirring, adding ethyl acetate into the concentrated crude sucralose solution, heating to a preset temperature, and holding at the preset temperature for a first preset time to obtain a crude product slurry with a certain amount of a sucralose crystal; and subjecting the crude product slurry to gradient cooling to an endpoint temperature, holding at the endpoint temperature for a second preset time, and filtering to obtain a sucralose crystal.

Abstract: Devices, systems, and methods for video processing are described. In one aspect, a video processing method is provided to include determining, for a conversion between a current video block of a video and a coded representation of the video, that a motion information of the current video block is refined using an optical flow-based method in which at least one motion vector offset is derived for a region within the current video block; clipping the at least one motion vector offset to a range [?N,M], where N and M are integers based on a rule; and performing the conversion based on at least one clipped motion vector offset.

Abstract: A photovoltaic system and a method for determining a combiner box set for the photovoltaic system are provided. The photovoltaic system includes a photovoltaic array divided into at least two combination groups, a photovoltaic converter, and a combiner box in at least one nonfinal stage and a combiner box in a final stage for each of the at least two combination groups. A direct current side of the photovoltaic converter is electrically connected to an output terminal of the combiner box in the final stage. The combiner box in the final stage and the combiner box in the at least one nonfinal stage are configured to combine outputs of photovoltaic strings in the combination group. Each combiner box combines multiple cables into a single cable.

Abstract: A temperature control device includes a temperature sensor configured to detect a temperature within a server. When the temperature in the server is below a preset temperature, the control unit controls an interior heating assembly to heat the server, and closes a ventilation assembly to retain heat within the server. When the temperature in the server has reached the preset temperature, the control unit controls the heating assembly to stop the internal heating, and controls the ventilation assembly to open, to allow dissipation of the heat from the server.

Abstract: An anti-IL5 nanoantibody, and a coding sequence for coding the anti-IL5 nanoantibody, a corresponding expression vector, a host cell capable of expressing the anti-IL5 nanoantibody, and a method for producing the anti-IL5 nanoantibody are provided. The nanoantibody can specifically recognize IL5 from humans and cynomolgus monkeys, does not recognize IL5 from mice, and has a good binding activity. The nanoantibody has a good IL5/IL5R blocking activity. The blocking activity is obviously superior to that of a control antibody Nucala. The nanoantibody can effectively inhibit the proliferation of TF-1 cells induced by IL5, and the inhibition activity thereof is superior to that of the control antibody Nucala. The expression yield of the nanoantibody in Pichia pastoris can reach 13 g/L, and the purity of target protein expressed in the supernatant is high.

Abstract: The present invention relates to the field of hemodialysis and peritoneal dialysis, in particular to a fat emulsion dialysate, and preparation method and the use thereof. Provided in the present invention is a fat emulsion dialysate, comprising a long-chain fat emulsion oil, a medium-chain triglyceride, an anti-oxidant, sodium oleate, glycerin, phospholipid, and a solvent. Compared with traditional dialysis, the fat emulsion dialysate provided by the present invention has a better advantage for protein-bound toxin removal. In addition, the fat emulsion dialysate not only has a simple preparation method and a low cost, but also has good stability and safety, and remains stable at room temperature for 14 days without obvious precipitation. Thus, the fat emulsion dialysate can become a hemodialysis dialysate or peritoneal dialysate with broad application prospects, and has good industrialization prospects.

Abstract: The present disclosure provides a preparation method of a 2?-substituted pyrimidine nucleoside, including the following steps: subjecting a compound of Formula I or Formula II to a series of process including dehydration, selective 5?-protection, ring-opening reaction using magnesium alkoxide and deprotection to obtain a 2?-substituted pyrimidine nucleoside of Formula VII or Formula VIII. In the present disclosure, the preparation method has desirable universality for different substrates; the ring-opening with a protected anhydrous pyrimidine nucleoside improves a solubility of the substrate, with milder reaction conditions than those of a traditional synthetic route; the formation of a dimer is avoided during the ring-opening to improve the yield; in addition, an intermediate (5?-O-bis-p-methoxytrityl-protected 2?-substituted pyrimidine nucleoside) can be directly used in synthesis of a corresponding phosphoramidite monomer, with a wider potential for use.

Abstract: An appliance performance report method for determining and communicating conditions of appliances. The method includes receiving appliance performance test parameters from a supervisory user of an appliance. The appliance performance test parameters include a test time frame for performing a self-diagnostic test. The method further includes directing the appliance to perform the self-diagnostic test during the test time frame, receiving diagnostic test data from the appliance following performance of the self-diagnostic test, generating a performance report using the diagnostic test data received from the appliance, and communicating the performance report to the supervisory user. An appliance performance report system including a controller is also described.