Abstract: Genetically modified microorganisms that have the ability to convert carbon substrates into chemical products such as 2,3-BDO; 1,4-BDO; isobutyraldehyde; isobutanol; 1-butanol; n-butanol; ethanol; fatty alcohols; and fatty acid methyl ester are disclosed. For example, genetically modified methanotrophs that are capable of generating 2,3-BDO; 1,4-BDO; isobutyraldehyde; isobutanol; 1-butanol; n-butanol; ethanol; fatty alcohols; and fatty acid methyl ester at high titers from a methane source are disclosed. Methods of making these genetically modified microorganisms and methods of using them are also disclosed. These microorganisms and methods make use of molecular switches to regulate gene expression.

Abstract: The present disclosure relates to a composition for immune enhancement or gut health improvement, which is fermented with a composition for fermentation containing any one or more selected from a Leuconostoc mesenteroides CJLM119 strain or a culture thereof and contains any one or more selected from a culture of Leuconostoc mesenteroides CJLM119 strain, a lysate thereof, an extract thereof, or a component derived therefrom.

Abstract: Provided are a fermented apple composition having an effect of reducing or inhibiting expression of inflammatory cytokines, and use thereof in the prevention or improvement of enteritis.

Abstract: Proposed is a technology that supports updating a machine learning model in a terminal or base station of a mobile communication system. The method where a core network supports a machine learning (ML) model update may include receiving by a first network function in the core network a model update request from a user equipment (UE) or a radio access network (RAN), obtaining by the first network function information for the model update on the basis of the received model update request and a communication with a second network function, and transferring by the first network function to the UE or the RAN a model update response including the information for the model update.

Abstract: The present disclosure relates to an adversarial attack method and apparatus. The adversarial attack method according to an embodiment of the present disclosure may include: selecting vulnerable positions of an original source code; acquiring open source codes based on an open source code set; selecting dissimilar codes among the open source codes based on dissimilarity of the open source codes; acquiring an attention score for each of the dissimilar codes; extracting a snippet from at least one of the dissimilar codes based on the attention scores; and generating an adversarial source code based on the at least one snippet.

Abstract: An unmanned charging device and method for a smart logistics vehicle are disclosed. The unmanned charging device includes a charging body configured to enable a mobile robot to dock therewith and having an inner space, and a charging terminal unit inserted into the inner space of the charging body and having a front support at a front side thereof, the charging terminal unit being configured to enable charging of the mobile robot. When the mobile robot approaches the charging body in response to reception of a charging request, a sensing unit of the mobile robot is supported by the front support, thereby causing the mobile robot to be adjusted in position. Docking of the mobile robot with the charging terminal unit is performed in a position-adjusted state of the mobile robot.

Abstract: One aspect of the present disclosure relates to a pharmaceutical composition for treating triple negative breast cancer, containing, as an active ingredient, a novel non-natural nucleic acid ligand that binds to both human serum albumin (HSA) and a G12D-mutation KRAS protein. The pharmaceutical composition exhibits an excellent effect on the treatment of primary or metastatic triple negative breast cancer, which is difficult to treat. In addition, one aspect of the present disclosure relates to a novel non-natural nucleic acid ligand binding to both human serum albumin (HAS) and a G12D-mutation KRAS protein, and a use thereof. The novel nucleic acid ligand may comprise a nucleic acid sequence of SEQ ID NO: 11 (GNA6AAG6CCGGA6GGCAGC666A6GC) [wherein, the second nucleic acid N is cystidine or gemcitabine and the part represented as 6 is 5-[N-(1-naphthylmethyl) carboxamide]-2?-deoxyuridine (Nap-dU)].

Abstract: One aspect of the present disclosure relates to a novel non-natural nucleic acid ligand that binds to human serum albumin (HSA), and to uses thereof. The novel non-natural nucleic acid ligand may include the nucleic acid sequence of SEQ ID NO: 8 (CAGG6CGAGC6G6ACGCG6G6G6GACC) [wherein the moiety indicated by 6 is 5-[N-(1-naphthylmethyl)carboxamide]-2?-deoxyuridine (Nap-dU)]. Meanwhile, one aspect of the present disclosure relates to a pharmaceutical composition for treating cancer, comprising a novel non-natural nucleic acid ligand that binds to human serum albumin as an active ingredient. The pharmaceutical composition exhibits excellent effects in the treatment of cancer.

Abstract: The present inventive concept provides a method for manufacturing a multi-layered nuclear fuel cladding pipe, comprising the steps of: providing a preliminary cladding pipe in which an inner pipe having a rod-shaped insertion body inserted thereinto is disposed in an outer pipe; reducing the diameter of the preliminary cladding pipe by applying pressure from the outside to the inner side of the preliminary cladding pipe; and removing the insertion body from the inner pipe by providing a force in the direction in which the insertion body extends, wherein the inner pipe and the outer pipe may be formed of different metals from each other.

Abstract: The present application relates to a resin composition or a use thereof. In the present application, it is possible to provide a resin composition or a cured body thereof that exhibits low adhesion force to a predetermined adherend while exhibiting high thermal conductivity. Also, in the present application, the low adhesion force can be achieved without using an adhesion force adjusting component such as a plasticizer or in a state where the use ratio thereof is minimized. The present application can also provide a product comprising the curable composition or the cured body thereof.

Abstract: The present disclosure relates to the composition and process for the production of an ultra-strong, biocompatible, electroconductive, and stretchable hydrogel, which comprises: a step (a) of physical or chemical modification of natural polymers e.g., preparation of silk nanofiber and double methacrylation of gelatin; a step (b) of graphene oxide (GO) carboxylation; a step (c) of carbodiimidation between methacrylated natural polymers of step (a) and carboxylated GO of step (b); and a step (d) of three dimensional (3D) bioprinting of step (c) with/without silk nanofiber. It was found that these steps in this disclosure give rise to a biocompatible hydrogel with high mechanical strength in the range of load-bearing soft tissue such as tendon and heart as opposed to conventional hydrogels.

Abstract: The present inventive concept provides a voltage generating apparatus for X-rays including a console that receives an X-ray irradiation signal to generate a control signal and detects the X-ray irradiation signal to generate a first detection signal, a pulse control unit that receives the control signal and the first detection signal from the console to generate a second detection signal and generates a pulse signal according to the control signal and the second detection signal, and a high voltage generating unit that generates a high voltage according to the pulse signal from the pulse control unit, and an X-ray generating apparatus having the same.

Abstract: The present inventive concept provides a method for manufacturing a filament including the steps of inserting and bonding an electrode having a desired length into a through-hole of a plate-shaped base to form a first part; bonding a wire having a desired length to one surface of a plate-shaped disc to form a second part; and bonding the electrode of the first part and the wire of the second part to form a filament, a filament manufactured by said method, and an X-ray tube having said filament.

Abstract: According to the present inventive concept, there is provided an X-ray generating apparatus including a voltage generating apparatus that generates a pulse signal according to an X-ray irradiation signal and generates a predetermined voltage according to the pulse signal, and an X-ray tube that generates X-rays according to the voltage from the voltage generating apparatus, wherein the voltage generating apparatus detects arc discharge by detecting a current of the X-ray tube.

Abstract: A resin composition comprising an oil-modified polyol component, and a filler, or a cured product thereof that exhibits low adhesion force to a predetermined adherend while exhibiting high thermal conductivity without using an adhesion force adjusting component such as a plasticizer or in a state where the use ratio thereof is minimized, are described herein.

Abstract: A display device includes: a display panel including a first substrate having a pixel area; and a cover layer. A rear surface of the first substrate is bonded to a front surface of the cover layer, and a linear flow path pattern is formed in at least one of the rear surface of the first substrate and the front surface of the cover layer at a depth from a corresponding surface.

Abstract: An electrode tab assembly includes an electrode tab having a width; and a reinforcing member located on at least one side portion of the electrode tab in a width direction to reinforce strength of the side portion of the electrode tab.

Abstract: An embodiment of a method for controlling a vehicle using a vehicle control apparatus includes determining a main occupant in a situation in which an occupant is in the vehicle, determining whether to change a route based on a conversation between the main occupant and a non-main occupant, a voice of the main occupant, or a facial expression of the main occupant, providing a determination result to the main occupant or the non-main occupant, wherein the determination result is displayed or announced by voice, and driving the vehicle based on the determination result.

Abstract: A drone integrated control device that controls a drone by unifying respective components on one board includes a flight control unit including a plurality of sensors and configured to control a path and a flight attitude of the drone, a motor control unit configured to control a rotation speed of at least one motor mounted to perform movements and takeoffs of the drone, a communication unit configured to transmit and receive control signals input to and output from the respective components included in the drone integrated control device, and a power supply unit configured to supply power to the respective components included in the drone integrated control device to operate the respective components.

Abstract: A curable composition or a thermal interface material exhibiting low adhesion force to a predetermined adherend while having a low density as well as exhibiting a high thermal conductivity is provided. It also has excellent flame retardant properties, and exhibits ejection properties and thixotropy suitable for processes in a state where halogen flame retardants or phosphorus-based flame retardants are not used, or the use ratio thereof is minimized.