Patents by Inventor An-Na Moon
An-Na Moon has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11970493Abstract: The present disclosure provides autotaxin (ATX) inhibitor compounds and compositions including said compounds. The present disclosure also provides methods of using said compounds and compositions for inhibiting ATX. Also provided are methods of preparing said compounds and compositions, and synthetic precursors of said compounds.Type: GrantFiled: October 4, 2021Date of Patent: April 30, 2024Assignee: ILDONG PHARMACEUTICAL CO., LTD.Inventors: Sung-Ku Choi, Yoon-Suk Lee, Sung-Wook Kwon, Kyung-Sun Kim, Jeong-Geun Kim, Jeong-Ah Kim, An-Na Moon, Sun-Young Park, Jun-Su Ban, Dong-Keun Song, Kyu-Sic Jang, Ju-Young Jung, Soo-Jin Lee
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Publication number: 20240072992Abstract: A homomorphic encryption operator includes: a level configuration unit configured to set an encryption level by selecting a plurality of prime numbers of different values according to a scale factor condition used for multiplication of a homomorphic encryption operation and an increase/decrease condition for increasing or decreasing consecutively selected prime numbers, and a modular multiplication operator configured to perform lightweight modular multiplication using the selected plurality of prime numbers, wherein the level configuration unit includes: a level constructor configured to select prime number sets whose number have selected Hamming weights, respectively, based on the scale factor condition and the increase/decrease condition, and wherein the level configuration unit is further configured to configure the selected prime number sets with the encryption level using a prime number table.Type: ApplicationFiled: May 5, 2023Publication date: February 29, 2024Inventors: YOUNG SIK MOON, JIYOUP KIM, HANBYEUL NA, HONG RAK SON, SEONGHYEOG CHOI
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Publication number: 20240041888Abstract: Adenosine receptor (e.g., A2A and/or A1 receptor) antagonist compounds and compositions including said compounds are disclosed. The present disclosure also provides methods of using said compounds and compositions for modulating (e.g., inhibiting or antagonizing) A2A and/or A1 receptor in a biological system. The compounds and compositions find use in various therapeutic applications including the treatment of central nervous system or neurodegenerative diseases, such as Parkinson's disease. The compounds and compositions may also find use in various therapeutic applications including the treatment of cancer and in immuno-oncology.Type: ApplicationFiled: October 2, 2023Publication date: February 8, 2024Applicant: ILDONG PHARMACEUTICAL CO., LTD.Inventors: Kyung-Sun KIM, Jeong-Ah KIM, An-Na MOON, DONG-Keun SONG, Yoon-Suk LEE, Ju-Young JUNG
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Publication number: 20240025162Abstract: Disclosed is a film for a shrinkable label with improved transparency and stiffness in the film for a shrinkable label using a non-adhesive polyolefin-based material. The present invention is a film for a shrinkable label, the film including a skin layer, a core layer, and a seal layer, wherein the skin layer and the seal layer include 70 parts by weight to 90 parts by weight of a cyclic olefin resin and 10 parts by weight to 30 parts by weight of a linear low-density polyethylene, and the core layer includes 5 parts by weight to 25 parts by weight of a cyclic olefin resin, 60 parts by weight to 85 parts by weight of a propylene copolymer, and 1 part by weight to 20 parts by weight of a modifier.Type: ApplicationFiled: November 10, 2021Publication date: January 25, 2024Inventors: Sun Hyung OH, Hyun Sup LEE, Tae Woo KIM, Jeong Min LEE, Yu Na MOON, Jun Ki KIM, Jik Soo SHIN, Byung Sam SON
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Patent number: 11806350Abstract: Adenosine receptor (e.g., A2A and/or A1 receptor) antagonist compounds and compositions including said compounds are disclosed. The present disclosure also provides methods of using said compounds and compositions for modulating (e.g., inhibiting or antagonizing) A2A and/or A1 receptor in a biological system. The compounds and compositions find use in various therapeutic applications including the treatment of central nervous system or neurodegenerative diseases, such as Parkinson's disease. The compounds and compositions may also find use in various therapeutic applications including the treatment of cancer and in immuno-oncology.Type: GrantFiled: November 17, 2021Date of Patent: November 7, 2023Assignee: ILDONG PHARMACEUTICAL CO., LTD.Inventors: Kyung-Sun Kim, Jeong-Ah Kim, An-Na Moon, Dong-Keun Song, Yoon-Suk Lee, Ju-Young Jung
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Publication number: 20230295644Abstract: Provided is a vector capable of co-expressing two different target proteins on the microbial surface using two promoters derived from Lactobacillus, and a method of expressing target proteins on the microbial surface using the vector. The vector containing foreign genes inserted therein is transformed into a microorganism, and allows different foreign proteins to be stably expressed on the surface of the microorganism. Furthermore, provided is a surface expression vector containing the gene pgsA encoding a poly-gamma-glutamate synthetase complex, and a method of expressing a target protein on the microbial surface using the vector. The vector containing foreign genes inserted therein is transformed into a microorganism, and allows the foreign proteins to be stably expressed on the surface of the microorganism.Type: ApplicationFiled: October 10, 2019Publication date: September 21, 2023Inventors: Young Chul PARK, Dae Eun KI, Gyeong Jun NAM, Se Eun BYEON, Ha Na MOON, Hyun Jun KANG, Kyung Soo HAHM
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Publication number: 20230159534Abstract: The present disclosure provides adenosine receptor (e.g., A2A and/or A1 receptor) antagonist compounds and compositions including said compounds. The present disclosure also provides methods of using said compounds and compositions for modulating (e.g., inhibiting or antagonizing) A2A and/or A1 receptor in a biological system. The compounds and compositions find use in various therapeutic applications including the treatment of cancer and in immuno-oncology. The compounds and compositions find use in various therapeutic applications including the treatment of central nervous system or neurodegenerative diseases, such as Parkinson’s disease.Type: ApplicationFiled: November 19, 2020Publication date: May 25, 2023Applicant: ILDONG PHARMACEUTICAL CO., LTD.Inventors: Yoon-Suk LEE, Sung-Wook KWON, Kyung-Sun KIM, Jeong-Geun KIM, Jeong-Ah KIM, An-Na MOON, Sun-Young PARK, Jun-Su BAN, Dong-Keun SONG, Ju-Young JUNG, Soo-Jin LEE
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Publication number: 20220380376Abstract: The present disclosure provides phosphodiesterase 5 (PDE-5) and/or phosphodiesterase 6 (PDE-6) inhibitor compounds and compositions including said compounds. In some embodiments, said compounds are nitrogen oxide (NO) donating PDE-5 and/or -6 inhibitor compounds that include a nitrogen oxide-containing donor substituent attached to a benzenesulfonamide group. The compounds can provide dual functionality for increasing protein kinase G (PKG) activity by inhibiting PDE-5 and PDE-6, and/or stimulating guanylate cyclase (sGC) via donation of nitrogen oxide (NO) from the donor substituent of the compound. The present disclosure also provides methods of using said compounds and compositions for inhibiting PDE-5 and/or -6 and increasing activity of protein kinase G (PKG). The compounds and compositions find use in therapeutic applications including in the treatment of a variety of eye diseases.Type: ApplicationFiled: May 10, 2022Publication date: December 1, 2022Inventors: Yoon-Suk LEE, Sung-Wook KWON, Kyung-Sun KIM, Jeong-Geun KIM, Jeong-Ah KIM, An-Na MOON, Sun-Young PARK, Jun-Su BAN, Dong-Keun SONG, Ju-Young JUNG, Soo-Jin LEE
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Publication number: 20220152034Abstract: Adenosine receptor (e.g., A2A and/or A1 receptor) antagonist compounds and compositions including said compounds are disclosed. The present disclosure also provides methods of using said compounds and compositions for modulating (e.g., inhibiting or antagonizing) A2A and/or A1 receptor in a biological system. The compounds and compositions find use in various therapeutic applications including the treatment of central nervous system or neurodegenerative diseases, such as Parkinson's disease. The compounds and compositions may also find use in various therapeutic applications including the treatment of cancer and in immuno-oncology.Type: ApplicationFiled: November 17, 2021Publication date: May 19, 2022Applicant: ILDONG PHARMACEUTICAL CO., LTD.Inventors: Kyung-Sun KIM, Jeong-Ah KIM, An-Na MOON, Dong-Keun SONG, Yoon-Suk LEE, Ju-Young JUNG
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Publication number: 20220153746Abstract: The present disclosure provides uses of phosphodiesterase 5 (PDE-5) and/or phosphodiesterase 6 (PDE-6) inhibitor compounds and uses of compositions including said compounds. In some embodiments, said compounds are nitrogen oxide (NO) donating PDE-5 and/or -6 inhibitor compounds that include a nitrogen oxide-containing donor substituent attached to a benzenesulfonamide group. The compounds can provide dual functionality for increasing protein kinase G (PKG) activity by inhibiting PDE-5 and PDE-6, and/or stimulating guanylate cyclase via donation of NO from the donor substituent of the compound. The present disclosure also provides methods of using said compounds and compositions for inhibiting PDE-5 and/or -6 and increasing activity of PKG. The compounds and compositions find use in the treatment of a variety of eye diseases.Type: ApplicationFiled: November 8, 2021Publication date: May 19, 2022Inventors: Yoon-Suk LEE, Kyung-Sun KIM, Jeong-Ah KIM, An-Na MOON, Dong-Keun SONG, Ju-Young JUNG
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Publication number: 20220106311Abstract: The present disclosure provides autotaxin (ATX) inhibitor compounds and compositions including said compounds. The present disclosure also provides methods of using said compounds and compositions for inhibiting ATX. Also provided are methods of preparing said compounds and compositions, and synthetic precursors of said compounds.Type: ApplicationFiled: October 4, 2021Publication date: April 7, 2022Inventors: Sung-Ku Choi, Yoon-Suk Lee, Sung-Wook Kwon, Kyung-Sun Kim, Jeong-Geun Kim, Jeong-Ah Kim, An-Na Moon, Sun-Young Park, Jun-Su Ban, Dong-Keun Song, Kyu-Sic Jang, Ju-Young Jung, Soo-Jin Lee
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Publication number: 20220033812Abstract: Provided is a galactose mutarotase gene promoter derived from Lactobacillus casei and the use thereof, and more particularly, to a Lactobacillus casei-derived galactose mutarotase gene promoter having the nucleotide sequence of SEQ ID NO: 1, an expression vector containing the promoter, and a microorganism transformed with the expression vector. A microorganism transformed with an expression vector containing the promoter may effectively express a target protein on the cell surface, and thus is useful as a vaccine vehicle or the like. Moreover, provided is a surface expression vector having pgsA, which is a gene encoding poly-gamma-glutamate synthetase, and a method of expressing a target protein on the microbial surface using the vector. The vector containing foreign genes inserted therein is transformed into a microorganism and allows a foreign protein is to be stably expressed on the surface of the microorganism.Type: ApplicationFiled: October 10, 2019Publication date: February 3, 2022Inventors: Young Chul PARK, Dae Eun KI, Gyeong Jun NAM, Se Eun BYEON, Ha Na MOON, Hyun Jun KANG, Kyung Soo HAHM
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Publication number: 20120309750Abstract: Disclosed are a novel 5-membered heterocycle derivatives of Formula I, a tautomer, pharmaceutically acceptable salt, prodrug thereof and a pharmaceutical use thereof. The 5-membered heterocycle derivatives of Formula I, a tautomer, pharmaceutically acceptable salt, prodrug thereof and compositions containing them are useful for treating a tumor.Type: ApplicationFiled: February 17, 2011Publication date: December 6, 2012Applicant: ILDONG PHARM CO., LTD.Inventors: Jae-Hoon Kang, Hong-Sub Lee, Jin-Sun Kwon, Joon-Tae Park, Chang-Sung Hong, Dong-Hyung Sin, Soo-Jung Hong, An-Na Moon, Jin-Ah Jeong, Sung-Wook Kwon