Abstract: The present disclosure relates to engineered RNA polymerase polypeptides and compositions thereof, as well as polynucleotides encoding the engineered RNA polymerase polypeptides. The present disclosure also provides methods of using the engineered RNA polymerase polypeptides or compositions thereof for producing RNA.

Abstract: Preparing a metal-containing solution or gel includes combining a metal oxide and a liquid comprising a polar organic solvent to yield a mixture, wherein the metal oxide comprises hydrogen-bonded molecular chains, and each molecular chain comprises: a metal from Groups 4-6; at least one oxyanion of a main group element from Groups 15 and 16 bound to the metal through a polar covalent bond, wherein the at least one oxyanion is optionally protonated; and at least one water molecule bound to the metal through a polar covalent bond; and heating the mixture to yield a solution or gel comprising the polar organic solvent and the metal. The solution or gel can be acidic.

Abstract: Disclosed herein are embodiments of a continuous multi-analyte monitor that can be used to measure one or more analytes, for example pH and lactate, in a patient. In some embodiments, the sensor can be implanted in the tissue of a patient, and a recording unit can be located on the skin of the patient, generally adjacent to the sensor. Detectors located on the sensor and on the recording unit can detect luminescent signals that originate from the implantable sensor and can be used to determine analyte concentrations, or otherwise relevant values.

Abstract: This document provides methods and materials involved in killing HIV infected cells (e.g., CD4 T cells). For example, methods and materials for using one or more Bcl-2 inhibitors (e.g., ABT-199) alone or in combination with one or more agents capable of reactivating HIV (e.g., latency reversing agent) to kill HIV infected cells (e.g., CD4 T cells) are provided.

Abstract: Disclosed herein is methods, systems, and aircraft for performing image analysis for aiding refueling operations. A tanker aircraft includes a single camera, a refueling boom, a camera configured to generate a 2D image of the refueling boom, a processor, and non-transitory computer readable storage media storing code. The code being executable by the processor to perform operations comprising receiving the 2D image from the single camera, determining 2D keypoints of the refueling boom located within the 2D image based on a predefined point model of the refueling boom, determining keypoints in 3D space based on the 2D keypoints to produce 3D keypoints, determining a 6DOF pose using the 2D keypoints and the 3D keypoints, and estimating a position of a tip of the refueling boom based on the 6DOF pose.

Abstract: Modular air cooling and distribution systems include a fan and heat exchanger cooling assembly and a controller which controls the fan speed based on temperature and velocity measurements. The cooling assembly includes a fluid-to-air heat exchanger and a variable speed fan. The fluid in the fluid-to-air heat exchanger may be propylene glycol or water. The heat exchanger minimizes pressure drop and maximizes heat transfer. The quantity of cooling assemblies is selected to match the indoor cooling requirements. The cooling assemblies are easily assembled together, stacked vertically, and/or connected horizontally, to match the cooling load. If additional cooling capacity is needed in the future, more cooling assemblies can easily be added, and the cooling assemblies may be expanded vertically and/or horizontally. The speed of the fans of the fan and heat exchanger assemblies are controlled based on fluid temperature and fluid velocity measurements, which may be obtained by an anemometer.

Abstract: A computer system is provided that includes one or more processors configured to receive user input for inked content to a digital canvas, and process the inked content to determine one or more writing regions. Each writing region includes recognized text and one or more document layout features associated with that writing region. The one or more processors are further configured to tokenize a target writing region of the one or more writing regions into a sequence of tokens, process the sequence of tokens of the target writing region using a task extraction subsystem that operates on tokens representing both the recognized text and the one or more document layout features of the target writing region, segment the target writing region into one or more sentence segments, and classify each of the one or more sentence segments as a task sentence or a non-task sentence.

Abstract: Delivery systems and methods of delivering devices or implants are disclosed. The devices or implants can be configured as valve repair devices or treatment devices have gripping members that are openable and closable to attach the device to leaflets of a native heart valve. The delivery systems are configured to position the device or implant and open and close the gripping members of the device or implant.

Abstract: A microfluidic device for processing a sample comprises an inlet port fluidically coupled to a closed system is disclosed. The closed system comprises a plurality of linear loading conduits, a plurality of terminating chambers, and pluralities of microchambers for receiving the sample. Also disclosed are methods for drawing sample amounts into microchambers of the microfluidic device. One method includes a step of applying a plurality of pressure pulses to contents within the microfluidic assemblies, the plurality of pressure pulses comprising a first pressure applied for a first time interval and a second pressure applied for a second time interval, wherein a volume of the sample is drawn into a plurality of microchambers of the microfluidic device. These and other embodiments of microfluidic devices and methods are disclosed.

Abstract: Methods, systems, and devices for wireless communications are described. An example method for wireless communication at a first user equipment (UE) may include receiving at least a first sidelink transmission from a second UE, wherein at least a second sidelink transmission from a third UE is scheduled contemporaneously with at least the first sidelink transmission from the second UE. The method may also include transmitting an indication in a transmission occasion to at least one of the second UE or the third UE based at least in part on a prioritization of information for the transmission occasion, wherein the indication indicates that at least the first sidelink transmission from the second UE is scheduled contemporaneously with at least the second sidelink transmission from at least the third UE.

Abstract: Disclosed herein are methods, systems, and aircraft for verifying performing automated refueling data. A method includes receiving a two-dimensional (2D) image from a camera, determining 2D keypoints of a target object located within the 2D image based on a predefined model of the target object, estimating a 6DOF pose based on the 2D keypoints and a three-dimensional model of the target object, generating an uncertainty value of the 6DOF pose, and outputting the uncertainty value of the 6DOF pose.

Abstract: This disclosure provides methods, components, devices and systems for radio frequency sensing control for an ultra-wideband system. Some aspects more specifically relate to setting up one or more sensing instances (sensing rounds) for one or more respective sensing operations. In some implementations, a first wireless device (for example a controller, an initiator) may transmit a sensing session setup request frame that indicates a set of parameters for the one or more sensing instances. For each of the sensing instances, the first wireless device may transmit a sensing control information element that includes at least a common sensing control configuration and a channel impulse response report configuration. The first wireless device may participate in the sensing operations with at least a second wireless device (for example one or more responders or controlees) during the respective sensing instances.

Abstract: A planar transformer includes: a first primary coil in a first layer of a printed circuit board (PCB); a first secondary coil in one or more second layers in the PCB; and a second secondary coil in the one or more second layers.

Abstract: The present disclosure relates to engineered RNA polymerase polypeptides and compositions thereof, as well as polynucleotides encoding the engineered RNA polymerase polypeptides. The present disclosure also provides methods of using the engineered RNA polymerase polypeptides or compositions thereof for producing RNA.

Abstract: Particular embodiments are directed to a payment service system associated with a payment service for facilitating recurring payment transactions to an external service utilizing a payment application. The payment service system receives a request to execute a payment transaction between a payor and a payee. The payment service system identifies, based on an identifier associated with the payee, a payee type for the payee, the payee type corresponding to a service provider having a payee account external to the payment service. The payment service system generates, based on the identified payee type for the payee, a transaction flow for executing the payment transaction, in which the transaction flow includes a customized sequence of user interactions to be performed to complete an execution to a payee having an account external to the payment service. In response to receiving one or more user inputs, the payment service system executes the payment transaction.

Abstract: A prosthesis for placement within a native heart valve preferably includes an expandable frame having locking tabs disposed along a proximal end. A plurality of distal anchors is disposed along a distal end of the frame. Each distal anchor is provided with a cushion cover. An outer fabric member surrounds the frame and may extend outwardly from the frame in an expanded condition for providing an improved seal in the region of a native annulus. A valve body is positioned within an interior of the expandable from for allowing blood flow in only one direction. In preferred embodiments, the cushions are positioned over enlarged head portions of the distal anchors for further reducing trauma on surrounding tissue.

Abstract: An electrochemical system comprises a plurality of stacked bipolar plates, each of which is composed of two structured half-plates that describe corrugation peaks and corrugation valleys. Coolant channels are formed between the half-plates of each bipolar plate by means of the corrugation peaks and corrugation valleys, and at the same time the outer faces of the bipolar plates delimit flow channels for operating media. A membrane assembly is located between each pair of bipolar plates. An assembly of flow channels, said assembly being mirror-symmetrical with respect to a plane on which the membrane assembly lies, transitions into an assembly which is offset in the transverse direction in a transition region between an active field and a distributing field of each bipolar plate.

Abstract: A modular control device including a plurality of electronic modules, module base, and at least two or more retention joints is provided. A mounting surface of the module base receives a retention surface of each plurality of electronic modules via the at least two or more retention joints. Each of the at least two or more retention joints have a module member associated with the retention surface and a base member associated with the mounting surface. The at least two or more retention joints are respectively positioned within a first portion and a second portion of the retention surface. The first portion and the second portion are equally a half surface area of the retention surface. The at least two or more retention joints respectively define a module interface and a retention interface. Each plurality of electronic modules is configured for input of control information.

Abstract: Certain aspects of the present disclosure provide a method for wireless communications at a first user equipment (UE). The first UE may detect at least one condition related to first resources reserved for sidelink transmissions in a first radio access technology (RAT). The first UE may perform one or more actions, based on the detection, to limit feedback request for sidelink transmissions in a second RAT.

Abstract: A memory device comprising an array of memory cells organized into a set of sub-blocks and a set of wordlines. Control logic is operatively coupled with the array of memory cells, the control logic to perform operations including: receiving a program command from a processing device, the program command including information indicative of a physical address associated with a retired wordline of the set of wordlines; in response to detecting the information within the program command, generating dummy data that is one of pseudo-random data, all one values, or all zero values; and causing the dummy data to be programmed to memory cells of multiple sub-blocks of the set of sub-blocks that are selectively connected to the retired wordline.