Abstract: The present invention provides a small molecule compound. The small molecule compound is a compound represented by the following formula (I), or a stereoisomer, geometric isomer, tautomer, hydrate, solvate, and pharmaceutically acceptable salt or prodrug thereof, wherein R1 to R5 are each independently selected from C or N; and R is selected from cycloalkyl, substituted cycloalkyl, heterocycloalkyl, substituted heterocycloalkyl, aryl, substituted aryl, heteroaryl, or substituted heteroaryl. The small molecule compound of the present invention can inhibit the JAK kinase, and is particularly used as a JAK1/Tyk2 dual inhibitor and a Tyk2 specific inhibitor.

Abstract: A pixel circuit, a driving method therefor, and a display panel. The pixel circuit includes a drive module, a data write module, a compensation module, a current leakage suppression module, and a first storage module. A first terminal of the compensation module is electrically connected to a second terminal of the drive module. The control terminal of the compensation module accesses a first light emission control signal. A first terminal of the current leakage suppression module is electrically connected to the control terminal of the drive module. A second terminal of the current leakage suppression module is electrically connected to a second terminal of the compensation module. The control terminal of the current leakage suppression module accesses the first light emission control signal. A first terminal of the first storage module is electrically connected to the second terminal of the compensation module.

Abstract: In a method for processing content of a cloud game, a cutscene is determined to be displayed in an instance of a cloud game. Cutscene identification information is generated based on the determination that the cutscene is to be displayed in the instance of the cloud game. The cutscene identification information indicates that the cutscene to be displayed. The cutscene identification information of the cutscene is sent to a cutscene server, which is configured to send cutscene data of the cutscene to a terminal device for display based on the cutscene identification information. The content of the instance of the cloud game to be displayed after the cutscene is rendered based on an end of the display of the cutscene. The rendered content is outputted to the terminal device for display after the display of the cutscene.

Abstract: This application relates to a method, an apparatus, and a system of power line communication (PLC) for the internet of things (IoT). The method includes: A sending device receives a first request from a receiving device, where the first request requests to perform channel assessment in a first time window in a power line communication periodicity; in response to the first request, the sending device sends a sounding signal required for performing channel assessment to the receiving device; the sending device receives a modulation parameter from the receiving device, where the modulation parameter is determined by performing channel assessment based on the sounding signal; and the sending device performs data transmission with the receiving device in the first time window based on the modulation parameter.

Abstract: The present invention relates to processes of preparing PD-1/PD-L1 inhibitor (R)-1-((7-cyano-2-(3?-(3-(((R)-3-hydroxypyrrolidin-1-yl)methyl)-1,7-naphthyridin-8-ylamino)-2,2?-dimethylbiphenyl-3-yl)benzo[d]oxazol-5-yl)methyl)pyrrolidine-3-carboxylic acid, or salts thereof, related synthetic intermediates, and salts of the intermediates, where the PD-1/PD-L1 inhibitor is useful in the treatment of various diseases including infectious diseases and cancer.

Abstract: Embodiments of the disclosure provide a method for encoding feature data, a method for decoding feature data, and a decoder. The method for encoding feature data includes the following. Feature data of multiple channels corresponding to a picture to-be-processed is obtained. Feature data of a reference channel in the feature data of the multiple channels is determined. Sorted feature data of the multiple channels is obtained by sorting, starting from the feature data of the reference channel, the feature data of the multiple channels in a descending order of similarity among the feature data of the multiple channels. The sorted feature data of the multiple channels is spliced to obtain a target feature frame sequence. The target feature frame sequence is encoded to generate a bitstream.

Abstract: A method, computer program, and computer system are provided for explaining generation of a flow from natural language utterances. Data corresponding to a natural language utterance is received. One or more constraints corresponding to a flow to be generated are determined based on the received natural language utterance. A flow is constructed based on the determined constraints. An explanation associated with the constructed flow is provided, and the explanation identifies parameters corresponding to constructing the flow.

Abstract: A suction nozzle device includes a large-diameter pipe, a large-diameter nozzle, a small-diameter pipe, a small-diameter nozzle, and a support mechanism for supporting the large-diameter and small-diameter pipes so as to be movable relative to each other. As the large-diameter and the small-diameter pipes move relative to each other, the large-diameter nozzle and the small-diameter nozzle selectively protrude. A nozzle can be selected from nozzles having different diameters, and the flow rate can be varied in accordance with the selection of the nozzle.

Abstract: A target tracking method and a target tracking system of a spiking neural network based on an event camera are provided. The method includes: acquiring a data stream of asynchronous events in a high dynamic scene of a target by an event camera as input data; dividing the data stream of the asynchronous events into synchronous event frames with millisecond time resolution; training a twin network based on a spiking neural network by a gradient substitution algorithm with a target image as a template image and a complete image as a searched image; and tracking the target by a trained twin network with interpolating a result of feature mapping to up-sample and obtaining the position of the target in an original image. The twin network includes a feature extractor and a cross-correlation calculator.

Abstract: A pixel circuit, a driving method of a pixel circuit, and a display panel. The pixel circuit includes an initialization module, a first storage module, a second storage module, a drive module, a data write module, a first light-emitting control module and a light-emitting module. The first light-emitting control module is connected between a first power supply and a first terminal of the drive module, the data write module is connected between a control terminal of the drive module and a data line, the light-emitting module is connected between a second terminal of the drive module and a second power supply, and the initialization module is configured to write an initialization voltage to the control terminal of the drive module and the light-emitting module in an initialization stage, and continuously write the initialization voltage to the control terminal of the drive module in a compensation stage.

Abstract: A method for forming a semiconductor device structure is provided. The method includes forming a first gate stack over a substrate. The first gate stack includes a first gate electrode and a dielectric layer between the first gate electrode and the substrate, and the first gate electrode has a void. The method includes oxidizing a side portion of the first gate electrode to form an oxide layer over the first gate electrode. The oxide layer fills the void.

Abstract: Embodiments of the disclosure provide an encoding method, a decoding method, an encoder, a decoder, and a storage medium. The method includes the following. An encoding result of a current block, a target index for the current block, and a block-coding enable flag for the current block are obtained by parsing a bitstream. A feature map splicing order is obtained. When the block-coding enable flag is valid, target block-coding motion information corresponding to the target index is determined based on the feature map splicing order and pixel position information of the current block. The encoding result of the current block is decoded based on the target block-coding motion information.

Abstract: Examples relate to a system for a microscope system, to a microscope system comprising such a system, and to a corresponding method and computer program. The system comprises one or more processors and one or more storage devices. The system is configured to obtain a trigger signal. The trigger signal indicates a desire of a user of the microscope system to display a visual representation of a control functionality associated with an input device of the microscope system. The system is configured to generate, based on the trigger signal, a visual overlay comprising the visual representation. The system is configured to provide a display signal to a display device of the microscope system, the display signal comprising the visual overlay.

Abstract: Methods and heat-treated cast aluminum alloy components for a vehicle formed from an aluminum alloy having high levels of recycled aluminum scrap are provided. The alloy may have, by mass, silicon at ?5% to ?11%, magnesium at ?0.5%, iron at ?0.2% to ?1.1%, copper at ?0.5%, zinc at ?0.5%, titanium at ?0.2%, chromium at ?0.02%, manganese at ?0.05%, strontium at ?200 ppm; an alloying element at ?50 ppm to ?500 ppm selected from the group consisting of: barium, lanthanum, samarium, europium, gadolinium, terbium, dysprosium, holmium, erbium, thulium, ytterbium, and combinations thereof, and a balance aluminum. The heat-treated cast aluminum alloy component is substantially free of faceted iron-containing intermetallics having a platelet shape and at least one region has a yield strength of ?180 MPa and an elongation of ?7%.

Abstract: Provided are a battery heating device and a control method and circuit therefor, and a power device. The battery heating device includes: a heating module including a first bridge arm, a second bridge arm, and an energy storage element; and a control module configured to control the first bridge arm and the second bridge arm, to form a circuit for discharging from a first battery cell to the energy storage element and a circuit for charging from the energy storage element and the first battery cell to a second battery cell, and/or to form a circuit for discharging from the second battery cell to the energy storage element and a circuit for charging from the energy storage element and the second battery cell to the first battery cell, for heating of the first battery cell and the second battery cell.

Abstract: A method, computer system, and a computer program product for data labeling is provided. The present invention may include receiving a plurality of labeled data points. The present invention may include identifying one or more of the plurality of labeled data points with conflicting labels. The present invention may include determining that at least one of the one or more identified labeled data points exceeds one or more conflict thresholds. The present invention may include presenting the at least one or more identified labeled data points exceeding one or more conflict thresholds to a user. The present invention may include receiving a conflict resolution from the user for the one or more identified labeled data points exceeding the one or more conflict thresholds.

Abstract: A self-contained actuator for use in a robot manipulator includes: a housing, in which are arranged in axial sequence a gear, a motor, a brake, a sensor and a motor drive. The motor drive includes wide-bandgap/WBG electronics and is arranged in heat-dissipating relationship with a free end of the housing. Through the motor and some further components, there is provided a central channel for receiving a cable connected to at least one further actuator of the robot manipulator. The channel may be angled or straight. In embodiments where the motor drive is hollow, the central channel extends between the axial ends of the actuator. There is further provided an all-in-one industrial robot comprising a robot manipulator, in which one or more self-contained actuators with the above characteristics are installed and a robot controller is physically integrated.

Abstract: An integrating sphere photometer spectral response measurement method and system. The system comprises an integrating sphere photometer and three or more reference light sources having different peak wavelengths. The integrating sphere photometer consists of an integrating sphere (1) and a broadband photodetector (2), and the broadband photodetector (2) is mounted on the sphere wall of the integrating sphere (1). Emergent light of the reference light sources is incident to the integrating sphere (1); the total spectral radiation flux Pi(?) (i=1, 2, . . . n) received by an integrating sphere photometer system is acquired; the response Mi (i=1, 2, . . . n) of a photometer of mixed light in the integrating sphere (1) is read by means of the broadband photodetector (2); an equation set is established; and the spectral responsivity Srel(?) of the integrating sphere photometer is obtained by means of numerical solution.

Abstract: The present invention discloses a neuromorphic computer supporting billions of neurons, comprising hierarchical extended architecture and algorithmic process control within the architecture; the architecture comprises multiple neuromorphic computing chips with hierarchical organization management for implementing computing tasks, each containing computing neurons and synaptic resources and forming a neural network, spike events between computing neurons within the architecture are transmitted through a hierarchical transmission mode; the algorithmic process control comprises controlling parallel processing of computing tasks within the architecture, controlling management of synchronization time within the architecture, and controlling reconstruction of neural networks within the architecture to achieve fault tolerance and robust management of computing neurons and synaptic resources. The neuromorphic computer can support spiking neural network inference calculations with a neuron scale of billions.