Abstract: Disclosed in the present invention is a synthesis method for high-purity cholesterol. The cholesterol is synthesized by using plant-derived 21-hydroxy-20-methylpregn-4-en-3-one, which is also referred to as bisnoralcohol or BA, as a raw material, and by means of steps of oxidation, Wittig reaction, acetylation, reduction, hydroxyl protection, selective hydrogenation reduction, and deprotection or hydrolysis reaction, and the purity can reach 99% or above. Aiming at defects of conventional animal-derived cholesterol, in the present invention, the cholesterol is synthesized from plant-derived raw material BA; thus, high safety is achieved, the risk of pathogenic bacteria and virus infection is avoided, high synthesis yield, high product purity, and environmental friendliness are achieved, and industrial production is facilitated.

Abstract: Provided herein are KRAS proteolysis targeting chimeras (PROTACs), compositions comprising the KRAS PROTACs, and methods of making and using the KRAS PROTACs, e.g., to promote degradation of KRAS and/or treat KRAS-associated cancers. In an embodiment, the KRAS PROTAC has the following structural formula: or a pharmaceutically acceptable salt thereof, wherein values for the variables are as described herein.

Abstract: A cell assembly includes a silicon substrate; a first doped region and a second doped region, having opposite polarities. The first doped region is an N-type doped region; the first doped region includes a first doped layer, a passivation layer, and a second doped layer; the passivation layer of the first doped region is provided on the first doped layer of the first doped region; and a conductive channel is formed in the passivation layer of the first doped region.

Abstract: A display screen and an electronic device are provided. The display screen includes a frame, a cover plate, and a display module. The cover plate and the display module are stacked on the frame. The display module includes a light-emitting unit. A surface of the cover plate is provided with an anti-glare layer formed by etching for scattering light emitted by the light-emitting unit and/or the display module includes a light-homogenizing structure for scattering the light emitted by the light-emitting unit.

Abstract: The present disclosure relates to methods and systems for providing an interactive platform to facilitate interaction between content creators and viewers. The method performed by a system includes obtaining media content performed by a content creator on an interactive platform through a first user device of the content creator. The method includes detecting a set of target objects in the media content of the content creator. The method includes generating an interaction element in response to detecting the set of target objects related to online adult entertainment in the media content of the content creator. The method includes executing an interaction mode for the interaction element. The interaction mode of the interaction element includes a first interaction mode and a second interaction mode. The interaction element facilitates interaction between the content creator and a plurality of viewers of the media content.

Abstract: A method and device for detecting an automatic closing function of a landing door, an elevator system and a non-transitory computer-readable storage medium. In the method for detecting the automatic closing function of the landing door, when a car of an elevator system stops at one of a plurality of floors, a car door of the car and a landing door associated with one of the plurality of floors are opened. Subsequently, during a closing process of the landing door, a drive mechanism of the elevator system is caused to apply a balanced driving force to the car door of the car. The balanced driving force corresponds to resistance to which the car door is subjected. Next, it is determined whether the associated landing door can be closed normally within a preset time period since the start of applying the balanced driving force to the car door.

Abstract: Systems and methods related to propulsion battery mount assemblies for micro-mobility transit vehicles are disclosed. For example, in an embodiment the battery mount assembly includes a mounting rail having a first side comprising a contoured surface configured to align with a complementary contoured surface of a frame of a micro-mobility transit vehicle and a second side comprising a battery mounting surface opposite the first side and configured to receive a first securing assembly and a second securing assembly entirely disposed thereon and separately spaced to receive a battery pack therebetween. The battery mount assembly may be installed on the frame of a micro-mobility transit vehicle to assist in expedient replacement of battery packs that electrically power the micro-mobility transit vehicle.

Abstract: Provided is a setting method for resilient checkpointing based on machine learning, which predicts a future power level in advance through a lightweight power level predictor and dynamically adjusts checkpoint intervals to accommodate a future energy input. During the operation of a power harvesting system, a resilient checkpointing mechanism assigns an appropriate checkpoint interval to a future power cycle to match a current harvesting power based on a state of a future harvesting power. Therefore, the power harvesting system with the resilient checkpointing mechanism can realize low checkpointing overhead and rollback punishment. The method involves a lightweight power level predictor based on a fully connected neural network and a resilient checkpoint setting mechanism based on power level prediction, which determines a checkpoint interval of a current cycle based on a predicted power level of a future power cycle.

Abstract: Systems, computer program products, and methods are described herein for enhanced encryption orchestration and application integration frameworks. The system performs steps of initializing a broker application to act as a data security broker within a computing environment; providing an application programming interface (API) for external application interaction; receiving and processing requests via the API for access to encrypted code and data; containerizing the code and data within an isolated environment, subject to predefined rules; monitoring usage to ensure adherence to these rules; initiating self-destruction of the container upon reaching a predetermined usage limit or condition; and securely erasing all sensitive data and code after usage completion.

Abstract: A wavelength multiplexing optical fiber transmitter, receiver, or transceiver where multiple emitters and/or photodetectors of different center wavelengths are coupled to a single optical fiber core terminus through multiple waveguides, which may be directly printed in free space. The optical assemblies described are suitable for optical data link applications, for example, to reduce a number of optical fibers needed for a given bandwidth or increase the bandwidth of a give number of optical fibers. Bidirectional fiber termination may also be implemented with an emitter and a photodetector pair coupled to a single optical fiber core terminus through multiple waveguides.

Abstract: Provided herein are compositions, methods, and systems for diagnosing orthopoxvirus infection in a subject and/or determining orthopoxvirus vaccination status in a subject.

Abstract: The present disclosure discloses a multi-sensor-based hot forming production system for an aluminum alloy sheet metal part and a control method thereof, and belongs to the field of aluminum alloy sheet metal forming manufacturing technology. A plurality of sensors are disposed in the hot forming production system, and closed-loop control of a whole process and adaptive production can be realized based on deformation properties, a microstructure evolution law, and a mechanical property change law of the aluminum alloy sheet metal part. The hot forming production system comprises a control system based on a multi-physical quantity model, an environmental heating furnace, an automated transfer and positioning device, a hot stamping and forming device, and an in-die aging device.

Abstract: This application discloses a one-inlet and two-outlet water pump which comprises a pump body, and an impeller assembly and a motor assembly set inside the pump body. The motor assembly is connected to the impeller assembly. The impeller assembly comprises the first impeller and the second impeller connected to each other, with a hollow cavity formed between the first impeller and the second impeller. The design rotation direction of the first impeller blade is opposite to that of the second impeller blade. An inlet is set at one end of the pump body, corresponding to one end of the first impeller away from the second impeller. A first outlet and a second outlet are set on a side wall of the pump body, with the first outlet and the second outlet offset by a certain angle along a circumferential direction.

Abstract: A method for eliminating jamming by OAM mode quadratic coordination is disclosed, including: a transmitter selecting a primary OAM mode and secondary OAM modes; based on a group of keys and real-time time self-defined by the transmitter and the receiver respectively, generating via the transmitter, a mode quadratic collaborative transformation sequence, and based on a mode quadratic collaborative transformation sequence, dividing input binary information bits into OAM mode index information bits and signal modulation bits, and jointly designing a position distribution of their bits in an information frame structure; determining via the transmitter, G quadratic collaborative transformation OAM modes carrying constellation point symbols activated at each hop, loading them onto each array element of an antenna to obtain G mutually orthogonal OAM mode quadratic collaborative transformation signals y, transmitting the G mutually orthogonal OAM mode quadratic collaborative transformation signals y to the receiver.

Abstract: A refrigerator includes a refrigerator main-body and an air blowing member. A storage room is provided inside the refrigerator main-body, an avoiding part in communication with the storage room is provided at the inner wall surface of the refrigerator main-body, at least part of the air blowing member is provided inside the avoiding part, and the air blowing member is for blowing air toward the storage room.

Abstract: A visual inspection system includes: a visual calibration apparatus, including a calibration member and a calibration member moving apparatus, where the calibration member moving apparatus includes a movable mounting plate, the mounting plate is able to be located at a calibration position within a movement range of the mounting plate, the calibration position is located within an inspection range of a visual inspection apparatus, and the calibration member is disposed on the mounting plate; the visual inspection apparatus, configured to obtain an image of the calibration member and send the image of the calibration member to an upper computer, and the upper computer, configured to determine, based on the image of the calibration member, a systematic calibration result of the visual inspection apparatus.

Abstract: An onboard refrigerator includes: a cabinet, a drawer, and a sliding component. The drawer is slidably provided inside the cabinet, the sliding component includes a first sliding member and a second sliding member, the first sliding member is provided on the drawer, the second sliding member is provided at an inner wall surface of the cabinet, the second sliding member has a sliding surface that is sliding-fitted to the first sliding member, and the sliding surface of the second sliding member and a plane orthogonal to a height direction of the cabinet have an included angle therebetween in a first direction, the first direction being orthogonal to the height direction and a front-rear direction of the cabinet.

Abstract: According to embodiments of the present disclosure, a method, apparatus, device and storage medium for content presentation are provided. The method comprises presenting, in a first display region of a content presentation page of an application, at least a portion of a first set of content items along a first arrangement orientation. The method further comprises presenting, in a second display region of the content presentation page of the application different from the first display region, at least a portion of a second set of content items along a second arrangement orientation different from the first arrangement orientation.

Abstract: A method according to an embodiment is for forming a capacitor structure on a wafer. A first capacitor is formed on a first side of a wafer, and a second capacitor is formed on a second side of the wafer. The capacitor structure includes the first capacitor and the second capacitor. A trench capacitor is fabricated at both ends of an interposer, which can increase capacitance, and greatly improve the stability of the supplied power.