Abstract: Methods, systems, and apparatus, including computer programs encoded on computer storage media, for identifying a plurality of n-grams in a plurality of resources found in a particular site; determining, for each of the plurality of resources, a count of n-grams that originated in the resource; determining, based on counts of n-grams that originated in the resources, a first aggregate count of n-grams that originated in the particular site; determining a second aggregate count of the plurality of n-grams that were identified in the plurality of resources found in the particular site; and determining, based on the first and second aggregate counts, a site originality score for the particular site.

Abstract: There is provided a process for preparing a perfluorovinyl ether sulfinate, comprising: a) providing a perfluorovinyl ether sulfonyl halide; and (b) reducing the perfluorovinyl ether sulfonyl halide with a reducing agent in an organic protic solvent.

Abstract: The present invention is directed to novel dihydropyrimidin-2(1H)-one compounds useful as Neurokinin-3 (NK3) receptor antagonists, pharmaceutical compositions comprising such compounds, and methods of making and using the same.

Abstract: The invention is related to a method for qualifying and quantifying carboxyl groups on the surfaces of a silicone hydrogel contact lens. The method of the invention comprises the steps of: (a) obtaining silicone hydrogel contact lenses each of which comprises a silicone hydrogel lens body (i.e., bulk material) and a coating thereon, wherein the silicone hydrogel lens body is obtained from a lens formulation free of any polymerizable component including one or more carboxyl groups, wherein the coating comprises a polymer having carboxyl groups; (b) immersing a given number of the silicone hydrogel contact lenses in a fixed volume of a C1-C4 alcohol solution of a positively-charged dye having acetate as counter anion at a given initial concentration for a time period sufficient to stain the silicone hydrogel contact lens; and (c) determining the concentration of carboxyl groups per each silicone hydrogel contact lens and/or the thickness of the coating on the silicone hydrogel contact lens.

Abstract: Described herein is an oligomer according to formula I: (I) wherein Y is an anionic group selected from the group consisting of: sulfates, carboxylates, phosphate, phosphonate, and sulfonate, wherein each X1, X2, and X3 are independently selected from F, Cl, H, and CF3; R is a linking group; each Z1 and Z2 is independently selected from F and CF3; m is at least 2; and R1 and R2 are end groups, wherein the oligomer comprises substantially no pendant functional groups, except those selected from the group consisting of: sulfates, carboxylates, phosphate, phosphonate, and sulfonate.

Abstract: A method that incorporates teachings of the present disclosure may include, for example, receiving an assignment to provide communication services to a communication device, supplying a first telephone number mapping system of a first internet protocol multimedia subsystem communication system with contact information of the communication device and a serving call session control function operating in the first internet protocol multimedia subsystem communication system, supplying a second telephone number mapping system of a second internet protocol multimedia subsystem communication system with contact information of the communication device and the serving call session control function, and receiving a session initiation protocol INVITE from an originating serving call session control function of the second internet protocol multimedia subsystem communication system for establishing communications with the communication device. Additional embodiments are disclosed.

Abstract: Described herein are compositions of Thyroid Stimulating Hormone (TSH), wherein at least one polyalkylene glycol polymer is attached to a carbohydrate site of the TSH. Also described are compositions of mutated Thyroid Stimulating Hormone (TSH) and at least one polyalkylene glycol polymer, wherein the mutated TSH comprises a TSH in which one or more amino acid residues has been substituted with cysteine residue, and the polyalkylene glycol polymer is attached to the mutated TSH at the site of the substituted cysteine residue. Pharmaceutical compositions comprising these TSH compositions and method of treating a thyroid condition in a patient in need thereof, by administering to the patient an effective amount of the pharmaceutical compositions are also described.

Abstract: Embodiments relate to an eigenvalue-based data query. An aspect includes receiving a query request that includes a query statement. Another aspect includes calculating eigenvalues of key component elements in the query statement. Another aspect includes matching eigenvalues of nodes in an execution plan of a historical query statement to the eigenvalues of the key component elements. Yet another aspect includes based on determining success of matching the eigenvalues of the key component elements to the eigenvalues of the nodes in an execution plan of the historical query statement, generating an execution plan of the query statement.

Abstract: This disclosure provides purified nucleic acids and polypeptides. Also provided are transgenic plants, seeds, and plant cells containing DNA for expression of the proteins that are useful for imparting enhanced agronomic trait(s) to transgenic crop plants, methods of making such plants and methods of making agricultural commodity including seeds and hybrid seeds from such plants.

Abstract: A toner particle includes a core including at least one resin, optionally a wax, and a colorant, and a shell comprising at least one charge control agent. The core is substantially free of the charge control agent. The toner particle has improved charging performance compared with core-shell toner particles having the charge control agent in the core of the toner particle.

Abstract: An LED driver system including an input receiving a rectified AC conductive angle modulated voltage on a rectified node, a converter, a low-pass filter, and AC detector, and a driver network. The converter is coupled to the rectified node and includes a power switching device coupled to a switching node, in which the power switching device is controlled to convert the rectified AC conductive angle modulated voltage to an output voltage and output current. The low-pass filter is configured to filter voltage of the switching node to provide a filtered voltage. The AC detector receives the filtered voltage and provides a current sense signal indicative thereof. The driver network controls duty cycle of the power switching device based on the current sense signal.

Abstract: A system that incorporates teachings of the present disclosure may include, for example, a server having a controller adapted to determine at least one network element to be designated as being in a probation mode where the network element is operably coupled to an Internet Protocol Multimedia Subsystem (IMS) network and is adapted to utilize Session Initiation Protocol, and determine communication devices to be designated as testing devices where the communication devices are user end point devices, wherein use of the network element for communication between user end points over the IMS network is limited to the testing devices. Other embodiments are disclosed.

Abstract: The invention provides isolated nucleic acid molecules which encode novel fatty acid dehydratase family members. The invention also provides recombinant expression vectors containing dehydratase nucleic acid molecules, host cells into which the expression vectors have been introduced, and methods for large-scale production of long chain polyunsaturated fatty acids (LCPUFAs), e.g., SDA, EPA and DHA.

Abstract: The invention relates to small molecules which function as inhibitors of the interaction between p53 and MDM2. The invention also relates to the use of these compounds for inhibiting cell growth, inducing cell death, inducing cell cycle arrest and/or sensitizing cells to additional agent(s).

Abstract: An electrical connector assembly includes a first connector and a second connector mating with the first connector in a mating direction. The first connector includes a mating portion defining two long walls opposite to each other and two short walls disposed oppositely, the long and short walls are connected to each other together to form a mating cavity. The second connector includes a mating tongue extending forwardly and a second shielding shell defining a mating frame surrounding the mating tongue. Wherein one of the long walls defines a pair of fool-proof portions extending outwardly from both sides thereof, the mating frame defines a pair of fool-proof slots and engaging with the fool-proof portions so as to prevent the first connector from mismating the second connector.

Abstract: A combined dish rack for feeding pets includes a main body and legs. The main body has two dish setting openings for positioning dishes. The main body and legs are detachably attached to each other. The main body on a bottom thereof has a plurality of protruding members. The legs have slots configured to receive the protruding members if the legs are attached to the main body. The legs are configured to be placed in a housing defined by a top wall and a side wall of the main body.

Abstract: Provided are a novel antibiotic preparation method and platform system based on the method, belonging to a novel drug development method. The method is based on a fixed structural formula: F—R, wherein F is an effect area, and R is an identification area. At the prior art level, the present invention can quickly develop a specific novel antibiotic for most pathogenic microorganisms or biological cells. Also provided is a platform for implementing the method, ensuring that the novel antibiotic is developed in an efficient streamlined process.

Abstract: The present invention generally relates to systems and methods for counting biomolecules or cells. In certain embodiments, the invention provides a cell counting or biomolecule counting system including: a covered chamber having a known height and configured to hold a suspension of biomolecules or cells in a sample; at least one fluorescent light source connected to at least one fluorescent light beam narrowing device; a bright-field light source connected to a bright-field light beam narrowing device; a microscope objective; a detection device; a fluorescent filter assembly to allow only excitation light to illuminate the sample and allow only emission light from the sample to be imaged by the detection device; and a movable light shutter to block bright-field light during fluorescent detection.

Abstract: A heat dissipation device for a moving-coil loudspeaker, comprising: a thermally conductive pad, a thermally conductive bar, and a heat sink, the thermally conductive pad, the thermally conductive bar and the heat sink being integrally mounted at an axially central portion of the loudspeaker; the thermally conductive bar is axially connected to the thermally conductive pad and the heat sink at top and bottom thereof respectively, the thermally conductive bar is axially provided with a through hole or a groove at a circle center thereof, the heat sink is axially provided with a through hole in which a screw is tapped, a central groove at a top end of the thermally conductive bar is aligned with a groove on the thermally conductive pad to form a straight line groove such that a communication passage leading to an exterior of the loudspeaker is for the electronic components on a circuit board.

Abstract: The present invention relates to a method for manufacturing a plurality of nanostructures comprising the steps of providing a plurality of protruding base structures (104) arranged on a surface of a first substrate (102), providing a seed layer mixture, comprising a solvent/dispersant and a seed material, in contact with the protruding base structures, providing a second substrate arranged in parallel with the first substrate adjacent to the protruding base structures, thereby enclosing a majority of the seed layer mixture between the first and second substrates, evaporating the solvent, thereby forming a seed layer (110) comprising the seed material on the protruding base structures, removing the second substrate, providing a growth mixture, comprising a growth agent, in contact with the seed layer, and controlling the temperature of the growth mixture so that nanostructures (114) are formed on the seed layer via chemical reaction in presence of the growth agent.