Abstract: Bifunctional compounds, which find utility as modulators of B-cell lymphoma 6 protein (BCL6; target protein), are described herein. In particular, the bifunctional compounds of the present disclosure contain on one end a cereblon ligand that binds to the respective E3 ubiquitin ligase and on the other end a moiety which binds the target protein, such that the target protein is placed in proximity to the ubiquitin ligase to effect degradation (and inhibition) of target protein. The bifunctional compounds of the present disclosure exhibit a broad range of pharmacological activities associated with degradation/inhibition of target protein. Diseases or disorders that result from aggregation or accumulation of the target protein are treated or prevented with compounds and compositions of the present disclosure.

Abstract: This application provides a composite positive electrode material and a preparation method thereof, a secondary battery, a battery group including the secondary battery, and an electric apparatus including the secondary battery. The composite positive electrode material includes a lithium-rich metal oxide and a positive electrode active material covering at least a partial surface of the lithium-rich metal oxide, where the positive electrode active material is formed through in-situ reaction between a positive electrode active material precursor and a free lithium compound on the surface of the lithium-rich metal oxide.

Abstract: A flight schedule optimization method based on a flight normality target is capable of carrying out pre-analysis on flight operation efficiency of a current flight schedule based on a national air traffic control service capability, and on this basis, generating a corresponding flight schedule adjustment suggestion according to a flight normality optimization target, which aims to provide a technical support means for carrying out flight schedule rationality analysis and optimization in strategic air traffic flow management.

Abstract: A display device includes: a plurality of backlight modules, where each backlight module includes a plurality of light sources capable of emitting light in at least three different colors; a color-filter-less liquid crystal display module including a plurality of pixel units arranged in an array form and a plurality of scanning lines coupled to the pixel units; where the plurality of backlight modules are arranged in parallel with the liquid crystal display module; where an orthogonal projection of each backlight module onto a plane where the liquid crystal display module is located corresponds to at least two rows of pixel units, where the pixel units in one row are along an length extension direction of each scanning line; and a driving circuit coupled to each backlight module and configured to apply a backlight driving signal to each backlight module.

Abstract: An apparatus and method for etching a material layer with a cyclic etching and deposition process. The method for etching a material layer on a substrate includes: (a) etching at least a portion of a material layer (302) on a substrate (101) in an etch chamber (100) to form an open feature (360) having a bottom surface (312) and sidewalls in the material layer (302); (b) forming a protection layer (314) on the sidewalls and the bottom surface (312) of the open feature (360) from a protection layer (314) gas mixture comprising at least one carbon-fluorine containing gas; (c) selectively removing the protection layer (314) formed on the bottom surface (312) of the open feature (360) from a bottom surface (312) open gas mixture comprising the carbon-fluorine containing gas; and (d) continuingly etching the material layer (302) from the bottom surface (312) of the open feature (360) until a desired depth of the open feature (360) is reached.

Abstract: A temperature control system and a driving method thereof, and a liquid crystal apparatus are provided.

Abstract: A radio bearer configuration method, an apparatus, and a system. The method includes: determining that a first sidelink radio bearer and a second sidelink radio bearer that are used during communication between the second terminal and a first terminal are associated with each other; and sending a first message to the first terminal, where the first message includes first indication information, and the first indication information is used to indicate that the first sidelink radio bearer is associated with the second sidelink radio bearer, where the first sidelink radio bearer is used by the first terminal to send first sidelink service data to the second terminal, and the second sidelink radio bearer is used by the second terminal to send a first radio link control RLC status report for the first sidelink service data to the first terminal.

Abstract: The present teaching relates to method, system, medium, and implementations for task management. When information related to at least one task to be carried out by a user is received, multiple features associated with each of the at least one task are predicted automatically based on a plurality prediction models, derived based on historic information related to the user in carrying out past tasks. The at least one task is then automatically scheduled in a calendar associated with the user based on the multiple features predicted for each of the at least one task to generate an updated calendar with the at least one task scheduled therein.

Abstract: Methods and apparatuses for transmitting synchronization signal in non-anchor carrier are disclosed. A method comprises transmitting a carrier configuration on an anchor carrier; and transmitting a synchronization signal in a non-anchor carrier based on the carrier configuration.

Abstract: A manufacturing data analyzing method and a manufacturing data analyzing device are provided. The manufacturing data analyzing method includes the following steps. Each of at least one numerical data, at least one image data and at least one text data is transformed into a vector. The vectors are gathered to obtain a combined vector. The combined vector is inputted into an inference model to obtain a defect cause and a modify suggestion.

Abstract: A display drive circuit, a drive method thereof, and a display device are disclosed. The display drive circuit includes: a pixel circuit and a compensation circuit, the pixel circuit includes: a drive transistor, a light emitting device, a storage capacitor, and includes: a gating sub-circuit configured to control connection and disconnection between the control electrode of the drive transistor and a control terminal of the compensation circuit and connection and disconnection between a second electrode of the light emitting device and a sensing terminal of the compensation circuit in response to a signal of a scanning line; the compensation circuit includes: a voltage generating sub-circuit configured to generate a sensing voltage according to the drive current and a target data voltage, and a voltage adjusting sub-circuit configured to adjust a voltage of the control terminal according to the sensing voltage and a voltage of a second power supply terminal.

Abstract: A bi-directional and double-punch balanced high-speed bodymaker includes a punch driving mechanism and blank pressing mechanism, wherein: the punch driving mechanism includes a crankshaft, two identical connecting rods, slide rails, sliders and punches. The crankshaft is rotationally supported by a bearing, and the crankshaft has a first crank, second crank and first and second blank pressing cams. Compared with the prior art, the swing lever and secondary connection are removed from each set of punch driving mechanism, simplifying the structure while maintaining all original functions, constituting omitting elements. It adopts two blank pressing cams and arranges the first blank pressing cam driving point of the opposite the second blank pressing cam driving point, and finally, the directions of the first and second torque are opposite and counteract each other, to maintain balance of overall torque on the plane passing the crankshaft axis during the operation of the bodymaker.

Abstract: A method of controlling a permanent magnet synchronous electric machine (PMSM) drive using a Deadbeat Predictive Current Control (DBPCC) scheme is provided. The method comprises: determining d-axis and q-axis stator current values (id, iq) representative of a measured PMSM current; determining d-axis and q-axis reference current values (id*, iq*); based on the stator current values (id, iq) and the reference current values (id*, iq*), determining d-axis and q-axis current correction values (Cd, Cq); determining corrected reference current values (id**, iq**) as a sum of the reference current values (id*, iq*) and the current correction values (Cd, Cq); and controlling the PMSM drive using the corrected reference current values (id**, iq**) as reference current inputs of the DBPCC scheme. A controller for performing the method; a system comprising the controller, a PMSM and associated power electronics; and a computer program for performing the method are also provided.

Abstract: Disclosed are a gate-on voltage generation circuit, a display panel driving device and a display device. The gate-on voltage generation circuit includes an on/off voltage output terminal, a power management integrated circuit and a voltage switching circuit. The power management integrated circuit includes a detection terminal connected to the on/off voltage output terminal, is configured for detecting a voltage output by the on/off voltage output terminal, and outputting first switch control signal or second switch control signal according to the voltage output from the on/off voltage output terminal. The voltage switching circuit includes a first input terminal for inputting a first voltage value and a second input terminal for inputting a second voltage value larger than the first voltage value. The voltage switching circuit outputs the first voltage value upon receiving the first switch control signal, and outputs the second voltage value upon receiving the second switch control signal.

Abstract: A nanoprobe system for in vivo use comprises a plasmonic-active nanoparticle and a molecular probe system. The molecular probe system comprises an oligonucleotide capable of forming a stem-loop configuration, having a first end and a second end, wherein the oligonucleotide is immobilized to the plasmonic-active nanoparticle at the first end and labeled with a Raman reporter at the second end, a placeholder strand at least partially bound to the oligonucleotide, and an attachment mechanism for attachment to a cell membrane.

Abstract: The invention features an image reader and a corresponding method for capturing a sharp distortion free image of a target, such as a one or two-dimensional bar code. In one embodiment, the image reader comprises a two-dimensional CMOS based image sensor array, a timing module, an illumination module, and a control module. The time during which the target is illuminated is referred to as the illumination period. The capture of the image by the image sensor array is driven by the timing module that, in one embodiment, is able to simultaneously expose substantially all of the pixels in the array. The time during which the pixels are collectively activated to photo-convert incident light into charge defines the exposure period for the sensor array. In one embodiment, at least a portion of the exposure period occurs during the illumination period.

Abstract: A color temperature calibration method includes: making a display screen display a test image at a target color temperature; measuring a chromaticity of a target pixel in the display screen to obtain measured color coordinates of the target pixel; comparing the measured color coordinates with standard color coordinates; if differences between the measured color coordinates and the standard color coordinates are greater than a target threshold, adjusting at least one of pixel values of the target pixel, until differences between re-obtained measured color coordinates and the standard color coordinates are not greater than the target threshold; and if differences between the measured color coordinates and the standard color coordinates are not greater than the target threshold, ending the color temperature calibration.

Abstract: A terminal according to an aspect of the present disclosure includes a control section that determine, in a case that reception of a plurality of downlink shared channels (PDSCHs) using a plurality of transmission configuration indication (TCI) states is configured, and spatial relation information is not configured for a specific UL transmission, the one or more spatial relations for the specific UL transmission, and a transmitting section that performs the specific UL transmission used for the one or more spatial relations. According to an aspect of the present disclosure, QCL parameters for multi-panel/TRP can be appropriately determined.

Abstract: A system and method for direct connect tissue fascia with a thin filiform needle piercing the skin, going underneath the skin into connective tissue fascia layer, to directly manipulate (stretch and vibrate) connective tissue fascia to reduce fascia adhesion/restriction and achieve efficient fascia release outcome.

Abstract: The present disclosure provides a radiation therapy device and a magnetic resonance guided radiation therapy system. The radiation therapy device may include an electron gun and a curved beam deflection unit. The beam deflection unit may be configured to accelerate an electron beam emitted from the electron gun within a magnetic field. The magnetic resonance guided radiation therapy system may include a radiation therapy device and a magnetic resonance imaging (MRI) device.