Abstract: The present invention is directed towards new chemical entities which primarily inhibit the human T-type calcium channels and differentially modulate other key ion channels to control cell excitability, and abnormal neuronal activity particularly involved in the development and maintenance of persistent or chronic pain, and/or neurological disorders. These novel compounds are useful in the treatment and prevention of neurological and psychiatric disorders and diseases in which these ion channels are involved. The invention is also directed towards pharmaceutical formulations comprising these compounds and the uses of these compounds.

Abstract: An example method to provide fault tolerance in a virtualized computing environment with a first host in a first fault domain and a second host in a second fault domain may include determining whether a primary virtualized computing instance and a secondary virtualized computing instance are both in the first fault domain. The secondary virtualized computing instance may be configured as a backup for the primary virtualized computing instance and supported by the first host. The method may further include: in response to determination that the primary virtualized computing instance and secondary virtualized computing instance are both in the first fault domain, selecting, from the second fault domain, the second host based on comparing a resource availability of each of a plurality of hosts that include the first host and the second host; and migrating the secondary virtualized computing instance from the first fault domain to the second fault domain.

Abstract: A method and apparatus for determining an auto white balance (AWB) gain based on determined depth information. The method may include receiving an image captured by an image sensor, determining depth information associated with the captured image, assigning weights to a plurality of illuminants based on the determined depth information, determining an auto white balance gain based on the assigned weights and statistics of the captured image, and applying the auto white balance gain to the captured image.

Abstract: The present disclosure provides a liquid crystal lens, comprising: an upper substrate, a lower substrate, and both a liquid crystal layer and spacers disposed between the upper substrate and the lower substrate; wherein the surfaces of the spacers are coated with ?/4 phase retardation film. Via the method of disposing a ?/4 phase retardation film on the surface of the spacers in the present disclosure, a part of light emitting into the ?/4 phase retardation film cannot be reflected from the film and then further decreasing leaking light caused from reflective light of spacers to achieving objects of increasing the contrast of the picture and improving 3D displaying efficiencies.

Abstract: The present disclosure provides a speech synthesis method and apparatus. The speech synthesis method includes: processing a text, to obtain a to-be-synthesized text; if a network connection exists, sending the to-be-synthesized text to an online speech synthesis system for speech synthesis; and if a fault occurs in the online speech synthesis system in a process in which the online speech synthesis system performs speech synthesis or the network connection is disrupted in an actual use process, sending a text for which the online speech synthesis system has not completed speech synthesis to an offline speech synthesis system for speech synthesis.

Abstract: An insulating mother board, an insulating harness mother board assembly and a battery module including the insulating mother board are provided. The insulating mother board includes a first end insulating board, a middle insulating board and a second end insulating board moveably connected in sequence. According to the insulating mother board, an arbitrary number of middle insulating boards can be arranged by arranging the first end insulating board and the second end insulating board on two ends of the insulating mother board respectively. There may be an arbitrary number of connection holes on the first end insulating board, the middle insulating board and the second end insulating board, each connection hole corresponds to one single battery. In this way, an assembly of different numbers of single batteries can be achieved.

Abstract: The method for sending the trunking paging includes: after receiving a group paging request, a base station sending a paging message to trunking terminals in a present cell in a predetermined paging time slot, wherein the paging message includes a group identification of a group needing to be paged. A base station for sending the trunking paging includes a receiving module and a sending module. A method for receiving the trunking paging includes: after monitoring a paging message, when determining that a group identity included in the paging message is the same as a group identity of the group to which the present terminal belongs, a trunking terminal accessing the group service, and sending a paging response to base station, or not sending a paging response to base station. A trunking terminal for receiving the trunking paging includes a monitoring module, a judging module and a group service processing module.

Abstract: Embodiments of the present invention provide a multimedia quality monitoring method, and a device. The method includes: determining reference quality of multimedia according to reference video quality and reference audio quality of the multimedia; acquiring multimedia distortion quality that is after video distortion and/or audio distortion of the multimedia occur/occurs; and determining quality of the multimedia according to the reference quality of the multimedia and the multimedia distortion quality. Therefore, accuracy of a multimedia quality monitoring result is improved.

Abstract: A method for automatically adapting to a Wi-Fi network with hidden service set identifier (SSID) is provided. The method includes a wireless access point (AP) hiding an SSID of the wireless AP and receiving a probe request frame containing request information for automatically adapting to a Wi-Fi network of the wireless AP within coverage of the wireless AP. The method also includes the wireless AP determining whether the probe request frame contains the request information for automatically adapting to the Wi-Fi network of the wireless AP and the wireless AP sending a probe response frame when the probe request frame contains the request information for automatically adapting to the Wi-Fi network of the wireless AP. Further, the method includes the wireless AP receiving a connection request sent by at least one Wi-Fi terminal, such that the at least one Wi-Fi terminal is connected to the Wi-Fi network wirelessly.

Abstract: Agents that specifically bind TIGIT are disclosed. The TIGIT-binding agents may include polypeptides, antibodies, and/or bispecific agents. Also disclosed are methods of using the agents for enhancing the immune response and/or treatment of diseases such as cancer.

Abstract: The disclosure discloses an array substrate, a liquid crystal display panel and a manufacturing method, the array substrate includes designing a data line layer and a light shield layer on a same layer, moreover, a source electrode layer, a drain electrode layer, an oxide semiconductor layer and a common electrode layer are designed on a same layer, the source electrode layer, the drain electrode layer and the common electrode layer are formed by doping the oxide semiconductor material, the source electrode layer, the drain electrode layer and the common electrode layer can be conductive by increasing conductivity thereof. By the method above, the disclosure can reduce the amount of masks in processes and costs in production significantly.

Abstract: A method for fabricating a semiconductor device includes forming a gate stack on a semiconductor substrate, forming a source/drain region on an exposed portion of the substrate, and forming a semiconductor material layer on the source/drain region. A first liner layer is deposited on the semiconductor material layer, and a second liner layer is deposited on the first liner layer. A conductive contact material is deposited on the second liner layer.

Abstract: Embodiments described herein provide a method for sealing a porous low-k dielectric film. The method includes forming a sealing layer on the porous low-k dielectric film using a cyclic process. The cyclic process includes repeating a sequence of depositing a sealing layer on the porous low-k dielectric film and treating the sealing layer until the sealing layer achieves a predetermined thickness. The treating of each intermediate sealing layer generates more reactive sites on the surface of each intermediate sealing layer, which improves the quality of the resulting sealing layer.

Abstract: The invention relates to the technical field of organic luminescent materials, in particular to a spirofluorene compound and a luminescent device thereof. Spiro difluorene compounds selected freely I compounds: Y1 and Y2 denote hydrogen, electron-absorbing groups or electron-donating groups independently, respectively; at least a substituent in X1 and X2 is the substituent shown in formula II; M denotes —S—, —P—, —SO—, —SO2—, —S(?S)—, —S(?S)(?S)—, —PO—, —PO2—, —P(?S)—, —P(?S)(?S)—, —C(?O)—; N1, N2, N3 and N4 denote carbon or nitrogen atoms independently, respectively; N is an integer of 0˜4. The spirobifluorene compound of the invention has A-D-A chemical structure, and a spatial dihedral angle of nearly 90° is formed between an electron D unit and an electron-absorbing A unit, which is good for HOMO-LUMO orbital separation of thermal activation of delayed fluorescence materials, in order to obtain ideal ?EST.

Abstract: A positioning information processing method and apparatus, where the method includes obtaining, by a terminal device, location information of at least two to-be-positioned targets, selecting, by the terminal device, a first to-be-positioned target from the at least two to-be-positioned targets according to the location information of all the to-be-positioned targets, displaying, by the terminal device, location information of the first to-be-positioned target, and indicating an orientation and a quantity of other to-be-positioned targets, different from the first to-be-positioned target, in the at least two to-be-positioned targets according to the location information of all the to-be-positioned targets.

Abstract: A method and system for updating nodes in a hierarchical data structure is described. The system receives an update to a first node representing a record in a hierarchical data structure. The system determines at least one other node that needs updating based on the update to the first node. The system compares the number of nodes that need updating based upon the update to the first node to a maximum number to determine whether the number of nodes that need updating is less than, equal to and greater than the maximum number. The system performs a synchronous update of the nodes that need updating in response to a determination that the number of nodes is less than or equal to the maximum number and an asynchronous update of the nodes that need updating in response to a determination that the number of nodes is greater than the maximum number.

Abstract: The present application discloses a touch substrate including a base substrate; a black matrix layer on the base substrate in a black matrix area of the touch substrate; and a touch electrode layer on a side of the black matrix layer distal to the base substrate in a touch electrode area of the touch substrate. The touch electrode area partially overlaps with the black matrix area thereby forming an overlapping area. The touch electrode layer includes a plurality of touch electrode blocks at least partially in the overlapping area. A touch electrode block at least partially in the overlapping area is spaced apart from adjacent touch electrode blocks by a first gap. The black matrix layer in at least a portion of a region on a side of the first gap proximal to the base substrate has a reduced thickness relative to a thickness of a remaining portion of the black matrix layer.

Abstract: An antiknock valve with both sides resisting a shock wave, and a valve body thereof. The antiknock valve includes a valve core (200) and two valve bodies (A3, A4). The valve body (A3/A4) includes a frame body (101/102), wherein two intersected supporters(2a, 2b/3a) are provided in the frame body (101/102) in a symmetrical manner, the supporters (2a, 2b/3a, 3b) intersect on a ridge-shaped column (2d/3d) and openings(2c1/3c2) are provided at intervals along the direction of the ridge-shaped column (2d/3d). The valve cores (200) are located above the openings (2c1/3c2) and the two valve bodies (A3, A4) are engaged and fixed; and one end of the valve core (200) is rotatably connected on the ridge-shaped column (2d/3d). Since the antiknock valve reduces the weight of the valve core (200), the antiknock capacity is improved, a closing speed is increases, and the antiknock valve is safer.

Abstract: An inkjet printing system includes an printhead with a nozzle face having nozzles arranged along an array direction. A pressure source is configured to provide a positive or negative pressure to an ink source. A valve is fluidically connected between the ink source and the inkjet printhead. A cleaning station is configured to confront the nozzle face across a gap. The cleaning station includes a cleaning fluid dispenser for dispensing cleaning fluid onto the nozzle face. The cleaning station includes a waste fluid collector having a vacuum inlet that is displaced from the cleaning fluid dispenser in a first direction for collecting dispensed cleaning fluid. The cleaning station includes a blower that is displaced from the cleaning fluid dispenser in a second direction opposite to the first direction. The blower is configured to direct a gas stream along the nozzle face to move dispensed cleaning fluid toward the vacuum inlet.

Abstract: There is provided a method in a wireless communications network, the method comprising: broadcasting a content stream as a broadcast service to at least one device using the wireless communications network; and sending to the at least one device a broadcast service status message, the broadcast service status message including the service areas for which the broadcast service will soon cease. By receiving an indication that the broadcast service will cease, before the broadcast service is stopped, the device can take steps to avoid buffer under-run, such as requesting and setting up a unicast service of the same content.