Patents by Inventor An Yan

An Yan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220016243
    Abstract: The present invention relates to methods, uses, and compositions for the treatment of cancer (e.g., a lung cancer; a cervical cancer; a breast cancer; a head and neck cancer; a liver cancer; a bladder cancer; a gastric cancer; an esophageal cancer; a pancreatic cancer; a kidney or renal cancer; a melanoma; an ovarian cancer; or a colorectal cancer). More specifically, the invention concerns the treatment of patients having cancer with an anti-TIGIT antagonist antibody, including treatment with an anti-TIGIT antagonist antibody in a combination therapy.
    Type: Application
    Filed: January 26, 2021
    Publication date: January 20, 2022
    Applicants: Genentech, Inc., Hoffmann-La Roche Inc.
    Inventors: Catherine LAI, Janet LAU, Anthony Jongha LEE, Shi LI, Yvonne Gail LIN-LIU, Christina Jeanne MATHENY, Diana MENDUS, Raymond D. MENG, Anh NGUYEN DUC, Jilpa Bhupendra PATEL, Thinh Quang PHAM, Isabelle Anne ROONEY, Heather Blythe STEVENS, Sarah Marie TROUTMAN, Lijia WANG, Yulei WANG, Patrick Georges Robert WILLIAMS, Benjamin WU, Yibing YAN, Aijing ZHANG, Xiaosong ZHANG, Marcus Dale BALLINGER, Hila BARAK, Elizabeth Alexandra BENNETT, Marcela Lucia CASTRO, Edward Namserk CHA, Hui Min Phyllis CHAN, Stephen CHUI, Christopher Roland COTTER, Viraj Vinay DEGAONKAR, Barbara Jennifer GITLITZ, Tien HOANG, Kimberly Mayumi KOMATSUBARA
  • Publication number: 20220020175
    Abstract: An object detection model training method, object detection method and related apparatus, relate to the field of artificial intelligence technologies such as computer vision, deep learning. An implementation includes: obtaining training sample data including a first remote sensing image and position annotation information of an anchor box of a subject to be detected in the first remote sensing image, where the position annotation information includes angle information of the anchor box relative to a preset direction; obtaining an object feature map of the first remote sensing image based on an object detection model, performing object detection on the subject to be detected based on the object feature map to obtain an object bounding box, and determining loss information between the anchor box and the object bounding box based on the angle information; updating a parameter of the object detection model based on the loss information.
    Type: Application
    Filed: September 30, 2021
    Publication date: January 20, 2022
    Inventors: Xiaodi WANG, Shumin HAN, Yuan FENG, Ying XIN, Bin ZHANG, Xiang LONG, Honghui ZHENG, Yan PENG, Zhuang JIA
  • Publication number: 20220019854
    Abstract: Techniques for unattended object detection using machine learning are disclosed. A machine learning policy, for use in identifying unattended objects in a captured image depicting one or more objects, is generated. The generating includes determining a level of occlusion in the captured image relating to the objects, and determining the machine learning policy based on the determined level of occlusion. A machine learning model is selected, from among a plurality of pre-defined machine learning models, based on the generated machine learning policy. An unattended object is detected in the captured image using the selected machine learning model.
    Type: Application
    Filed: July 16, 2020
    Publication date: January 20, 2022
    Inventors: Rong YAN, Shi Lei ZHANG, Junsong WANG, Ke Wei SUN
  • Publication number: 20220016612
    Abstract: The disclosure relates to molecularly-imprinted cross-linked micelles that can selectively hydrolyze carbohydrates.
    Type: Application
    Filed: July 6, 2021
    Publication date: January 20, 2022
    Inventor: Yan Zhao
  • Publication number: 20220015338
    Abstract: Provided herein are screening methods and animal models related to intraocular diseases such as age-related macular degeneration (AMD), for example, for identifying candidate therapeutics for treating or preventing eye diseases, such as AMD. Also provided herein are compounds/compositions that are useful for killing or inhibiting the growth of a microorganism, such as Bacillus megaterium. Further provided herein are methods of using the compounds/compositions for treating infections with a microorganism, such as Bacillus megaterium and for treating or preventing diseases or disorders associated with such infections, such as AMD.
    Type: Application
    Filed: November 12, 2019
    Publication date: January 20, 2022
    Inventors: Yan ZHANG, Lai WEI, Hui OUYANG
  • Publication number: 20220021349
    Abstract: The disclosure discloses a digital predistortion (DPD) device and method. The DPD device comprises a predistorter configured to obtain a predistortion component from a digital baseband signal using a predistortion parameter and output the predistortion component; and a weighting unit configured to: obtain one or more weighted predistortion components by applying the predistortion component to one or more weighting coefficients, and obtain one or more predistortion correction signals by combining the digital baseband signal and the one or more weighted predistortion components, wherein the one or more weighting coefficients are determined based on the digital baseband signal, the predistortion component, and a synthesized signal in a main lobe direction obtained by combining radio frequency signals from a beamforming array.
    Type: Application
    Filed: December 18, 2019
    Publication date: January 20, 2022
    Inventor: Jia YAN
  • Publication number: 20220020227
    Abstract: The present invention relates to the technical field of two-dimensional (2D)/three-dimensional (3D) modeling, and in particular to a method, system, and device for combining models in a virtual scene, and a medium. The method of the present invention includes: placing a first model into a second model; determining a filling space and a removing space of the first model; filling an overlapping space between the first model and the second model with the second model, and filling the filling space of the first model with the second model; and removing the second model with which the removing space of the first model is filled, wherein when the overlapping space between the first model and the second model is filled with the second model, and the filling space of the first model is filled with the second model, the removing space of the first model is filled with the second model. The present invention simplifies a workflow of a scene designer, reduces repetitive work, and achieves a desired effect of the models.
    Type: Application
    Filed: September 25, 2019
    Publication date: January 20, 2022
    Inventors: Yan ZHOU, Di WU
  • Publication number: 20220021756
    Abstract: Systems and methods provide secure, end-to-end high-speed data encoding and communication. In certain embodiments, this is accomplished by modifying a header portion of a data packet received from a first device and complying with a one Mobile Industry Processor Interface (MIPI) protocol to create a modified data packet that complies with a faster MIPI protocol. The header portion of the modified data packet is validated during a tunnel mode operation using an error detection process to validate the modified data packet, which can then be securely transmitted to a second device that complies with the faster MIPI protocol.
    Type: Application
    Filed: July 14, 2021
    Publication date: January 20, 2022
    Applicant: Maxim Integrated Products, Inc.
    Inventors: Paul FULLER, Yan YAN, Gary MURDOCK, Prem Ramachandran NAYAR
  • Publication number: 20220019719
    Abstract: An amplification method for a metallurgical process includes the following steps: determining a general rate equation by a metallurgical macrokinetics research method, and determining the most critical technology steps which affect a reaction rate to obtain reaction characteristics; determining physical field characteristics of a reactor to optimize the reactor by a physical simulation method and/or a numerical simulation method; according to the reaction characteristics and the physical field characteristics of the reactor, determining a single factor of a reaction period; according to an affection relationship in a metallurgical reaction process, determining a single factor amplification number; and solving pilot-scale test results by a hot state experiment or a simulation means, verifying an amplification criterion, obtaining an amplification scheme, performing industrialization, and completing metallurgical process amplification.
    Type: Application
    Filed: December 10, 2018
    Publication date: January 20, 2022
    Inventors: Tingan ZHANG, Zhihe DOU, Yan LIU, Zimu ZHANG, Qiuyue ZHAO, Guozhi LV, Jicheng HE
  • Publication number: 20220019587
    Abstract: A computer-implemented method for access path optimization is provided according to embodiments of the present disclosure. In the method, a plurality of real values of an access path factor may be collected during a specified time period. One of the real values may be generated when a query is executed on a first access path. Then, at least one second access path may be generated for the query based on the plurality of real values of the access path factor. Moreover, an optimal access path for the query may be identified from the first access path and the at least one second access path.
    Type: Application
    Filed: July 17, 2020
    Publication date: January 20, 2022
    Inventors: Xiao Xiao Chen, Xiaobo Wang, Shuo Li, Sheng Yan Sun
  • Publication number: 20220017167
    Abstract: The disclosure relates to an unmanned vehicle chassis (1). The unmanned vehicle chassis (1) comprises at least two chassis units (11), the at least two chassis units (11) being spliced to form the unmanned vehicle chassis (1). The unmanned vehicle chassis (1) is formed by splicing at least two chassis units (11), so unmanned vehicle chassis (1) of different sizes can be formed by splicing different numbers of chassis units (11) to carry cargo boxes of different sizes, without the need to specially design and develop different chassis for cargo boxes of different sizes, thereby reducing the research and development cost. The disclosure also relates to an unmanned vehicle.
    Type: Application
    Filed: August 7, 2019
    Publication date: January 20, 2022
    Applicant: BEIJING JINGDONG QIANSHI TECHNOLOGY CO., LTD.
    Inventors: Zhanhui ZHANG, Ming WANG, Shuchao WANG, Lian SHAO, Yingchun YAN
  • Publication number: 20220022188
    Abstract: Apparatus, methods, and computer-readable media for facilitating per bandwidth part TCI state or spatial relation are disclosed herein. For example, aspects disclosed herein provide techniques for enabling a UE (e.g., a reduced capability UE) to associate at least one of a TCI state or a spatial relation with respective hopping regions. An example method for wireless communication at a UE includes determining, while communicating using a first frequency range comprising a first set of frequency hops, at least one of a TCI state or a spatial relation for communicating using a second frequency range comprising a second set of frequency hops. The example method also includes communicating, after switching communication from the first frequency range to the second frequency range, using the second frequency range based on the determined at least one of the TCI state or the spatial relation.
    Type: Application
    Filed: June 8, 2021
    Publication date: January 20, 2022
    Inventors: Iyab Issam SAKHNINI, Tao LUO, Olufunmilola Omolade AWONIYI-OTERI, Yan ZHOU, Wanshi CHEN, Juan MONTOJO, Peter GAAL, Qiang WU, Mahmoud TAHERZADEH BOROUJENI, Junyi LI, Jelena DAMNJANOVIC
  • Publication number: 20220019574
    Abstract: Systems and methods for pre-allocating and utilizing storage space in a relational database are provided. In embodiments a method includes: obtaining transaction data including data regarding record insertions in a relational database, wherein each record of the record insertions is associated with a key value; identifying a type of each of the record insertions as either a random insertion type or a key range insertion type based on the database transaction data, wherein the random insertion type comprises records associated with respective key values inserted in a random order, and the key range insert type comprises records associated with a range of key values inserted within a certain time period; predicting a new range of key values associated with future record insertions based on the type of each of the record insertions; and pre-allocating page space in one or more pages of the relational database for the future record insertions.
    Type: Application
    Filed: July 17, 2020
    Publication date: January 20, 2022
    Inventors: Frances Hwa VILLAFUERTE, Hong Mei ZHANG, Xiaobo WANG, Shuo LI, Sheng Yan SUN
  • Publication number: 20220017825
    Abstract: A method for preparing biochar and hydrogen by utilizing anaerobic fermentation byproducts, the method including: (1) mixing a first straw, seeding sludge and distilled water, and then carrying out anaerobic fermentation to obtain a mixed product after fermentation; (2) performing separation on the mixed product to obtain a second straw and biogas slurry; and (3) carbonizing the second straw to obtain biochar, and collecting gas after a pressurized catalytic reaction on the biogas slurry to obtain hydrogen.
    Type: Application
    Filed: October 16, 2019
    Publication date: January 20, 2022
    Applicant: TIANJIN UNIVERSITY
    Inventors: Guanyi CHEN, Xiang GUO, Yurou MAO, Beibei YAN, Yanbin ZHANG, Junyu TAO, Wanqing LI, Zhanjun CHENG, Wenchao MA
  • Publication number: 20220021790
    Abstract: Disclosed are a camera module and a method thereof, and a terminal which relates to the field of camera technology. The camera comprises a circuit board, a sensitive chip, a bracket, and a sealing member. At least one side of the bracket is an open side, and a receiving cavity is defined between a surface of the open side facing the circuit board and a first surface of the circuit board. The sealing member is filled in the receiving cavity. The camera module improves the space utilization efficiency, reduces the width of the open side, increases the screen-to-body ratio of the terminal, and improves user's perception and user experience.
    Type: Application
    Filed: November 7, 2019
    Publication date: January 20, 2022
    Applicant: Kunshan QTech Microelectronics Co., Ltd.
    Inventors: Aiguo DENG, Yangliu XU, Yuanbin JIN, Huanhuan YAN
  • Publication number: 20220021963
    Abstract: The present disclosure provides an acoustic output apparatus. The acoustic output apparatus may include an acoustic output component and a supporting structure forming an acoustically open structure that allows the acoustic output component to acoustically communicate with the surroundings. The acoustic output component may include a plurality of acoustic drivers, each of which may be configured to output a sound with a frequency range. At least one of the acoustic drivers may include a magnetic system for generating a first magnetic field. The magnetic system may include a first magnetic component for generating a second magnetic field and at least one second magnetic component. A magnetic gap may be formed between the first magnetic component and the at least one second magnetic component. A magnetic field intensity of the first magnetic field in the magnetic gap may be greater than that of the second magnetic field in the magnetic gap.
    Type: Application
    Filed: September 30, 2021
    Publication date: January 20, 2022
    Applicant: SHENZHEN VOXTECH CO., LTD.
    Inventors: Lei ZHANG, Junjiang FU, Bingyan YAN, Fengyun LIAO, Xin QI
  • Publication number: 20220021228
    Abstract: The invention discloses a spherical magnetic charging cable and its assembling process, including a wire, a net tail, a contact spring pin, and a metal butt joint. A first shell is nested on the outer end of the wire, and the net tail is arranged through the inside of the first shell, and the net tail is connected with the wire. A light-emitting PCB is nested inside the net tail, and the light-emitting PCB is connected to the end of the wire. A magnet is arranged at the outer end of the net tail, and a contact spring pin is nested at the middle end of the magnet. A plurality of spring plates are fixedly connected to the outside of the PCB sheet, and these spring plates are connected to the light-emitting PCB, and the spring plates and the outer sides of the PCB sheet are nested with an encapsulation.
    Type: Application
    Filed: July 15, 2020
    Publication date: January 20, 2022
    Inventors: RUMENG YAN, FUJUN ZENG
  • Publication number: 20220017621
    Abstract: This invention relates generally to a combination therapy for the treatment of cancer, particularly to a combination of (i) a bifunctional molecule comprising a TGF?RII or fragment thereof capable of binding TGF? and an antibody, or antigen binding fragment thereof, that binds to an immune checkpoint protein, such as Programmed Death Ligand 1 (PD-L1) and (ii) at least one additional anti-cancer therapeutic agent.
    Type: Application
    Filed: June 24, 2021
    Publication date: January 20, 2022
    Inventors: Kin-Ming Lo, Yan Lan
  • Publication number: 20220021441
    Abstract: An instrument landing system comprises: a wideband antenna configured to receive signals in a VHF band; and a receiver coupled to the wideband antenna and configured to implement SDR functions to analyze the signals for a flight inspection. A UAS comprises: an instrument landing system comprising: a wideband antenna configured to receive signals in a VHF band; and a receiver coupled to the wideband antenna and configured to implement SDR functions to analyze the signals for a flight inspection. A method comprises: receiving, using a wideband antenna, signals in a VHF band; and implementing, using a receiver coupled to the wideband antenna, SDR functions to analyze the signals for a flight inspection.
    Type: Application
    Filed: July 20, 2021
    Publication date: January 20, 2022
    Inventors: Yan Zhang, Hernan A. Suarez Montalvo, Sudantha Perera
  • Publication number: 20220016729
    Abstract: Provided is a femtosecond laser system for processing a micro-hole array, comprising: a femtosecond laser, a half-wave plate, a polarizer, a concave lens, a convex lens, a diaphragm, a mechanical shutter, a phase-type spatial light modulator, a first plano-convex lens, a reflecting mirror, a second plano-convex lens, a dichroic mirror, a camera, a processing objective lens, a six-axis translation stage and a transmissive white light source.
    Type: Application
    Filed: September 29, 2021
    Publication date: January 20, 2022
    Inventors: Lan JIANG, Jianfeng YAN, Jiaqun LI