Abstract: A focal adhesion kinase (FAK) inhibitor compound, a composition containing the compound, and a use of the compound. The compound has a good treatment effect on cancer, pulmonary hypertension, and pathological angiogenesis, and has good clinical application prospects.

Abstract: Disclosed is a Lactobacillus plantarum and an application thereof in the production of urolithin A, belonging to the technical field of biology. The disclosure provides a Lactiplantibacillus plantarum CCFM1290 preserved in Guangdong Microbial Culture Collection Center (GDMCC) with a preservation number of GDMCC No: 62801 and a preservation date of Sep. 15, 2022. The L. plantarum CCFM1290 may convert ETs into various Uros represented by Uro-A. A fermented product or compound preparation provided by the disclosure may relieve muscle function damage. Compared with a control group, the fermented product and compound preparation may improve the swimming capability of Caenorhabditis elegans by 33.84% and 27.99%. Finally, Uro-type substances such as Uro-A obtained by this biosynthesis method may be applied to functional food development to achieve beneficial effects of delaying senescence, keeping muscles healthy, etc.

Abstract: The present disclosure provides a stacked nanosheet gate-all-around device with an air spacer and a manufacturing method. The device includes: a substrate, where a first dielectric layer is on the substrate, a gap array is in the first dielectric layer, the gap array includes multiple gap units, and each gap unit is in a fin shape above the substrate; a nanosheet stacking portion above the gap unit, including a stack formed by multiple nanosheets, and the stack formed by the nanosheets constitutes multiple conductive channels; a gate-all-around surrounding the nanosheet stacking portion; and a source/drain region on two opposite sides of the nanosheet stacking portion, where an empty spacer is between the source/drain region and the gate-all-around. An interior of the gap array and an interior of the empty spacer are filled with at least one of air, a reducing gas, or an inert gas.

Abstract: A first data management apparatus in a plurality of data management apparatuses corresponds to a first blockchain node in a blockchain network, and a second data management apparatus corresponds to a second blockchain node in the blockchain network. A storage mounted to the first data management apparatus and a storage mounted to the second data management apparatus are configured to form a storage resource pool of the blockchain network. A method includes a target data management apparatus in the plurality of data management apparatuses that receives a data operation request; and that the target data management apparatus obtains a storage address of a plurality of data shards of target data from the blockchain network based on the data operation request, and performs I/O on the target data in the storage resource pool based on the storage address of the plurality of data shards.

Abstract: The present disclosure discloses an apparatus, a method, and a device for regulating a control parameter of an excitation system and a medium. The apparatus includes a parameter obtaining module and an excitation regulation module. The parameter obtaining module is connected to a first potential transformer and a second potential transformer to obtain a voltage signal of a pumped storage generator through the first potential transformer. The excitation control module is connected to an excitation system and the parameter obtaining module to obtain a current ratio of an output voltage of the pumped storage generator to a voltage of the power grid according to the voltage signal of the pumped storage generator and the voltage signal of the power grid, and obtain a target control parameter regulation strategy for the excitation system according to the current ratio.

Abstract: The present disclosure describes a semiconductor structure that is resistant to induced eddy currents. The semiconductor device includes a substrate, a device layer having electronic devices on the substrate, and a metallization layer above the device layer. The first metallization layer includes first and second terminal traces, a switch, and capacitors. A first terminal of a capacitor of the capacitors is coupled to the first terminal trace via the switch. A second terminal of the capacitor is coupled to the second terminal trace. The first and second terminal traces are disposed along the same side of the capacitors.

Abstract: Described in certain example embodiments herein are programmable nuclease-peptidase compositions, systems, and methods for the manipulation of nucleic acids and/or polypeptides. In some embodiments, the programmable nuclease-peptidase composition comprises a repeat-associated mysterious protein (RAMP) polypeptide; a guide molecule capable of forming a RAMP-guide molecule complex with the RAMP polypeptide and directing sequence specific binding of the complex to a target polynucleotide; and a peptidase capable of binding to the RAMP polypeptide, the guide molecule, or further complexing with the RAMP-guide molecule complex, wherein binding of the RAMP-guide molecule complex to the target polynucleotide initiates binding and/or interaction of the peptidase with a target polypeptide.

Abstract: Methods, systems, and devices for wireless communications are described that provide for full-duplex communications at both a user equipment (UE) and a serving network entity in which the UE, the network entity, or both can dynamically change from full-duplex communications to half-duplex communications. A UE may be configured for full-duplex communications for a set of symbols, and may receive an indication to switch one or more symbols to a half-duplex configuration. The half-duplex configuration may correspond to an indicated half-duplex configuration in which both the network entity and UE operate in the half-duplex configuration, or may correspond to a full-duplex configuration of the network entity in which the UE operates in half-duplex and the network operates in the full-duplex configuration. Signaling that indicates one or more symbols to be switched to the half-duplex configuration may be provided in downlink control information, medium access control signaling, or both.

Abstract: A method for testing and controlling a rapid shutdown device, and a tester are provided. The method includes: transmitting a heartbeat signal of first signal strength to a target rapid shutdown device in a target rapid shutdown module to switch the target rapid shutdown device on and testing the target rapid shutdown device using a preset testing program t, on receipt of a rapid shutdown device testing request, where all rapid shutdown devices in the target rapid shutdown module are previously off; and transmitting a heartbeat signal of second signal strength to the target rapid shutdown module to switch the rapid shutdown devices on or off, on receipt of a rapid shutdown device control request, where the first signal strength is lower than the second signal strength. The rapid shutdown devices can be tested and controlled efficiently, thereby effectively avoiding safety hazards and thus protecting workers.

Abstract: Provided are an anti-CLDN-18.2 antibody-drug conjugate that specifically binds to CLDN-18.2 and a composition comprising same. Also provided are a method for using the antibody-drug conjugate of the present invention and a use thereof.

Abstract: Embodiments of the disclosure are drawn to apparatuses and methods for row hammer counter resets. Repeated access to an aggressor word line may cause increased data degradation in nearby victim word lines of the memory. The access count value of a given word line may be stored in counter memory cells positioned along that word line. The count values may be randomly or pseudo-randomly initialized. In some examples, a memory device may utilize residual charges that are present on the counter cells during start-up to initialize the counter memory cells. In some other examples, a memory device may utilize threshold voltage compensation (VtC) settings at start-up to initialize the counter memory cells. In some other examples, a memory device may utilize a combination of the residual charges that are present on the counter cells and VtC settings on start-up to initialize the counter memory cells.

Abstract: A system and method for providing a short-term power bridging architecture, particularly tailored to improvements in electrochemical cell packs that include an aggregation of electrochemical cells having at least one electrode using a TMCCC. A rack architecture for a power bridging rack, includes a power path; and a low voltage path; wherein elements disposed in the power path include protection elements and provide a protection function; wherein the low voltage path is divided into a control section and an interface section; wherein the control section provides a balance function; and wherein the interface section interfaces to one or more devices.

Abstract: A method for improving DAS signal-to-noise ratio by means of local FK transform. The method includes: acquiring seismic wavefield data; segmenting the seismic wavefield data into a plurality of pieces of local data, wherein each piece of local data has the same dimension as the seismic wavefield data; processing each piece of local data by means of the following steps: performing FK transform to obtain an intermediate signal, removing some FK spectrum components from the intermediate signal according to scanning energy which corresponds to the intermediate signal under different apparent slowness, and performing two-dimensional inverse FFT on the intermediate signal, from which some FK spectrum components are removed; and combining all the processed local data, so as to obtain new seismic wavefield data.

Abstract: A method and apparatus may be used in multi-AP and multi-wireless transmit/receive unit joint transmissions. The apparatus may be configured to transmit a joint transmission request on a first medium, and receive a joint transmission response on the first medium. In response, the apparatus my perform a joint transmission negotiation on a second medium and transmit data on the second medium based on the joint transmission negotiation. The apparatus may be configured to perform coordinated sectorized or beamformed transmissions through access point (AP)/PCP negotiations. The apparatus may provide an indication of support for joint transmission and coordinated sectorized or beamformed transmissions. The method and apparatus may also implement multi-AP/WTRU request-to-send (RTS)/clear-to-send (CTS) procedures. The apparatus may be configured to perform coordinated sectorized or beamforming grouping.

Abstract: An organic aluminum sol and a preparation method thereof related to chemical technology fields. Organic mixed acids are used to react with aluminum powder to prepare organic aluminum sol as a precursor for preparing alumina fiber. The aluminum powder, formic acid, and oxalic acid are used as raw materials, the oxalic acid and the formic acid are firstly mixed to be even according to a preset ratio to obtain a mixed acid solution, and the aluminum powder is then completely reacted with the mixed acid solution to obtain an aluminum carboxylate solution under a condensation reflux condition, and the aluminum carboxylate solution is finally filtered to obtain the aluminum carboxylate sol that is clear and transparent. A chemical formula of a composition of the organic aluminum sol is expressed as: Al(OH)x(HCOO)y(COO—COO)z, wherein 0<x<2, 0<y<2, and 0<z<1.

Abstract: The present disclosure relates to a display panel and a display device. In the display panel, multiple transfer lines are arranged in a layer different from a layer in which first signal lines are located, and the transfer lines are connected to parts of the first signal lines close to bending sections through transfer holes. Multiple transfer holes are close to an edge of a non-display area along a first direction in sequence and are away from the edge of the non-display area along a second direction in sequence.

Abstract: Provided are a microfluidic substrate, and a microfluidic chip. The microfluidic substrate includes a flow channel structure, the flow channel structure includes a conveying flow channel including an input end and an output end; a recovery assembly including a waste liquid tank, and a second micro flow channel in communication with the waste liquid tank at one end and in communication with the output end of the conveying flow channel at another end; and multiple detection assemblies arranged between the input end and the output end. Each detection assembly includes a first fluid tank, a first micro flow channel and a second fluid tank, which are in communication in turn. The first fluid tank communicates with the conveying flow channel, and a reagent is provided in at least one second fluid tank. A critical rotational speed of the first micro flow channel for blocking a fluid is set as a first rotational speed, and the second micro flow channel is configured to block the fluid at the first rotational speed.

Abstract: In an approach, a processor performs document layout analysis on a document generating a plurality of textual regions; extracts characteristics from each of the plurality of textual regions and associates the respective characteristics to the respective textual region as metadata; classifies each of the plurality of textual regions as an optical character recognition (OCR) region, non-OCR valuable region, or non-OCR non-valuable region using a classifier; performs OCR on each OCR region generating an OCR output; identifies associated constant OCR data from a constant OCR data repository for each non-OCR valuable region; merges the associated constant OCR data with the OCR output generating a complete OCR data for the received document; performs data extraction on the complete OCR data to identify data fields and key-value pairs generating extracted data; and determines whether the extracted data is valid based on a set of rules.

Abstract: A method and apparatus for data writing and reading relate to the field of storage. The data writing method includes: during data writing, re-sorting various subdata contained in target data to generate a writing sequence, wherein the writing sequence is different from an original arrangement sequence of the subdata in the target data; executing writing operation on the subdata according to the writing sequence; and locking the writing sequence, or prohibiting execution of an action for generating the writing sequence after determining that the writing operation is executed on all the subdata. By re-sorting the subdata of the target data and writing the data in a manner of disturbing the original arrangement sequence, the difficulty in cracking data stored in a memory can be increased, and the security of data storage can be ensured.

Abstract: An implementation method for a paper-based visually identifiable anti-counterfeiting electronic seal is achieved through functional software that is configured with an authentication communication interface. An electronic seal pattern includes a fixed information part and a dynamic information part, and the later includes an associated code of stamped sample and an associated code of authorized counterpart. An operator needs to provide a communication tool number of an authorized counterpart, serving as an associated code to be embedded into the seal pattern for intuitive display. The software binds the code to stamped samples, permitting the authorized counterpart to authenticate, extract, or consult the samples through a communication tool. Using the authentication communication interface, the authorized counterpart can perform anti-counterfeiting verification on the stamped samples.