Abstract: The present application relates to a hydrogen peroxide-responsive Keap1-Nrf2 PPI inhibitor prodrug, and a preparation method therefor. The hydrogen peroxide-responsive Keap1-Nrf2 PPI inhibitor prodrug pro2 has a chemical structure as shown below. By modifying a key carboxyl pharmacophore in a Keap1-Nrf2 inhibitor with a H2O2-responsive thiazolidinone moiety, a novel ROS-responsive antioxidant prodrug pro2 is synthesized. The H2O2 activated prodrug pro2 can simultaneously achieve targeted activation of Nrf2 and enhancement of therapeutic efficacy in the body. The prodrug is based on the concept of ROS activation-ROS clearance therapy, is the first example of a H2O2-responsive prodrug suitable for oral administration, and is expected to be used clinically by virtue of the characteristics of druggability and high targeting ability.

Abstract: A water pH detection sensor and a use of a ruthenium-iridium electrode as a PH sensing material. The water pH detection sensor includes a ruthenium-iridium electrode and a reference electrode, and the pH value of a solution to be detected is obtained by means of a voltage between the ruthenium-iridium electrode and the reference electrode. The ruthenium-iridium electrode is used as the pH sensing material, the electrode potential of the material in a solution has a good linear correspondingly relationship with a hydrogen ion concentration, and the material has the features of a wide pH value response range, a high response speed, a stable response performance and repeated measurement and use, and is suitable for different practical application scenarios.

Abstract: An optical imaging lens includes six lens elements. The object-side surface of the first lens element has a convex part in a vicinity of the periphery of the first lens element, the image-side surface of the second lens element has a concave part in a vicinity of the periphery of the first lens element, the object-side surface of the third lens element has a convex part in a vicinity of the optical axis, the image-side surface of the fourth lens element has a convex part in a vicinity of the periphery of the fourth lens element, the image-side surface of the fifth lens element has a concave part in a vicinity of the optical axis, and the sixth lens element has negative refractive power.

Abstract: An array substrate, a detection method for the array substrate, and a tiled display panel. In the array substrate, each of pixels (1) comprises sub-pixels (01) of at least three colors and a. pixel driving chip (02) for driving each sub-pixel (01) to emit light; each sub-pixel (01) comprises at least one inorganic light-emitting diode; a display area (A1) further comprises: a positive signal line (Tian) connected to a positive electrode of each inorganic light-emitting diode, and a data signal line (Din), a scanning line (Sn), and a reference signal line (Vm) connected to each pixel driving chip (02); each pixel driving chip (02) is used for writing signals of the data signal line (Dm) into the sub-pixels (01) of different colors under the control of the corresponding scanning line (Sn) in a time division manner.

Abstract: The present invention discloses an acrylate oligomer, the acrylate oligomer is obtained by a reaction of isocyanate group-terminated oligomer and formate-terminated ethylene glycol methacrylate. After the acrylate oligomer provided by the present invention is photocured, the molecular structure, cross-linking density and other network structure characteristics of the acrylate oligomer can be changed through specific post-processing. Since the formate component formed after heat treatment has no water absorption and has a low glass transition temperature, the final material obtained after heat treatment has a lower water absorption rate and glass transition temperature. The present invention also provides a preparation method and an application method of the acrylate oligomer.

Abstract: A method of treating microbial biomass includes mixing the microbial biomass in a liquid to form a suspension, the microbial biomass having an initial color, and exposing the suspension to light to form treated microbial biomass, the treated microbial biomass having a treated color. The treated color is lighter than the initial color. The microbial biomass can also have an initial taste and odor that are stronger than a treated taste and odor of the treated microbial biomass.

Abstract: The present disclosure provides a three-dimensional hydrogel-graphene-based biosensor and a preparation method thereof, belonging to the technical field of biosensors. The present disclosure provides a three-dimensional hydrogel-graphene-based biosensor, including a substrate, an electrode layer, a graphene film, and a three-dimensional hydrogel material layer that are stacked in sequence; where the three-dimensional hydrogel material layer is formed of a hydrogel material having a three-dimensional network structure; the hydrogel material is obtained by polymerization of raw materials including an acrylamide monomer and a modified probe molecule; and the modified probe molecule is a probe molecule modified with an acrylamide group. The three-dimensional hydrogel-graphene-based biosensor has a desirable stability and a high sensitivity.

Abstract: Signal transmission method and device, signal reception method and device and a terminal are provided. The signal transmission method includes: transmitting P synchronous signal blocks SSBs in a synchronous period, wherein the P SSBs are divided into Q groups, any of the Q groups includes at least one SSB, both P and Q are positive integers greater than or equal to 1; when a synchronization period includes at least two SSBs, a time-domain location of at least one of the SSBs is preconfigured or carried through a physical broadcast channel PBCH.

Abstract: The present application relates to anti-TIGIT antibodies or antigen binding fragments thereof, nucleic acid encoding the same, therapeutic compositions thereof, and their use to enhance T-cell function to upregulate cell-mediated immune responses and for the treatment of T cell dysfunctional disorders, such as tumor immunity, for the treatment of infectious diseases and cancer.

Abstract: Techniques disclosed herein cope with temperature effects in non-volatile memory systems. A control circuit is configured to sense a current temperature of the memory system and read, verify, program, and erase data in non-volatile memory cells by modifying one or more read/verify/program/erase parameters based on a temperature compensation value. The control circuit is further configured to read, verify, program, and erase data by accessing a historical temperature value stored in the memory system, the historical temperature value comprising a temperature at which a previous read, verify, program or erase occurred and measuring a current temperature value. The control circuit determines the temperature compensation value by applying a smoothing function.

Abstract: Apparatuses, systems, and techniques to evaluate layers of a neural network. In at least one embodiment, one or more layers of a neural network are evaluated based, at least in part, on a single memory access.

Abstract: A display method for a display assembly, a display system, and a display device of a vehicle column A, and a storage medium. According to the display method, by means of a conversion relationship between a coordinate system of a target feature model and a camera coordinate system of a driver monitoring assembly and a conversion relationship between the coordinate system of the target feature model and a world coordinate system, a conversion relationship between the camera coordinate system and the world coordinate system is obtained, a coordinate of the display assembly in the world coordinate system can be converted into a coordinate in the camera coordinate system, and thus whether a driver watches the display assembly can be simply determined.

Abstract: The present disclosure provides a method for preparing an interlayer insulating layer and a method for manufacturing a thin film transistor, and a thin film transistor, belongs to the field of display technology, and can solve the problem of poor resistance to breakdown of the interlayer insulating layer in the related art. The method for preparing an interlayer insulating layer includes the following steps: forming a silicon oxide layer with a first reaction gas and forming a silicon nitride layer with a second reaction gas such that hydrogen content in the silicon nitride layer is less than or equal to hydrogen content in the silicon oxide layer.

Abstract: An image decoding method performed by a decoding apparatus, according to the present document, comprises the steps of: acquiring image information comprising a flag indicating whether or not one chroma quantization parameter table is to be applied with respect to chroma components, and prediction information and residual information regarding the chroma components; on the basis of the flag, deriving a chroma quantization parameter for the chroma components; deriving residual samples for the chroma components on the basis of the residual information and the chroma quantization parameter; and generating a reconstructed picture on the basis of prediction samples, which have been derived on the basis of the prediction information, and the residual samples.

Abstract: A system for testing linear displacement of multiple linear motors simultaneously under various signals and electrical power supplies includes a testing device, a first processing device, and a second processing device. The first processing device outputs a first start signal to a plurality of first motors to control operation of the plurality of first motors. The second processing device receives a test start signal output by the first processing device, and outputs a first test trigger signal to the test device according to the test start signal. The testing device receives the first test trigger signal, and measures displacements of the moving end of the first motor according to the first test trigger signal.

Abstract: The disclosed technology is generally directed towards, for interworking function interworking group call services, configuring each of the interworking groups with a separate group home server, with the servers coupled to one another via an interworking function. The interworking function receives a floor taken message from one server, and, in response, obtains a floor grant from the other server, which facilitates communication from a device to which the floor was granted to other devices, including devices associated with the other server. If the interworking function receives colliding floor taken messages from both servers, the interworking function performs mediation to determine which server/user has a higher priority level. The interworking function acknowledges the floor taken message to the higher priority server, and sends a floor request (with high priority) message to the other server, which triggers a floor revoke message to a device on the lower priority side.

Abstract: Systems and methods for enhancing wellness in a habitable space are provided. In some forms, an example system for enhancing wellness in a habitable space includes a control system having a processor, communication circuitry, and a memory. The communication circuitry of the control system is configured to communicate with one or more devices positioned within the habitable space. One or more sensors may also be positioned proximate the habitable space to detect indicia (e.g., biometric characteristics of a user, behavioral characteristics of a user, and environmental characteristics) and communicate the detected indicia to the control system. Based at least in part on the detected indicia, the control system is configured to trigger initiation of a scene in the habitable space by communicating a signal to at least one of the devices in the habitable space to adjust operation thereof.

Abstract: Disclosed is an improved fuel cell apparatus. The fuel cell apparatus comprises at least one fuel cell, the fuel cell comprising two bipolar plates (200a 200b), one providing an anode side, and the other providing a cathode side, the fuel cell being configured to have a fuel inlet and a fuel outlet, and a membrane electrode assembly (422) disposed between the fuel inlets (201) and fuel outlets (203) of the bipolar plates. The at least one fuel cell is retained by a housing, the housing comprising a first outer plate and a second outer plate, each located on an opposite face of the at least one fuel cell. The housing further comprises a cooling element support which is adapted to support one or more fans that are adapted to provide an air flow toward the at least one fuel cell.

Abstract: A handover method and a communication apparatus are provided. The method includes: A target access network device obtains a first message and information used for transmitting multicast data, where the first message is used for requesting to establish a resource for handing over a terminal device to the target access network device. The target access network device sends a second message, where the second message indicates the established resource on the target access network device; receives a first packet from a user plane network element, where the first packet corresponds to the information used for transmitting the multicast data; and sends the first packet to the terminal device. In this way, the terminal device is handed over from a source access network device to the target access network device when the terminal device receives the multicast data.

Abstract: Disclosed are a power grid-friendly control method and system for a data center cooling system. The method includes: dividing an equipment room into a plurality of pieces of subspace in advance, with a plurality of servers and a cooling device comprised in each piece of subspace; obtaining total power consumption of the servers in each piece of subspace; performing priority sorting on the total power consumption of the servers in each piece of subspace; obtaining a real-time power supply energy consumption value of a power grid; determining, whether an energy supply is sufficient; and if the energy supply is sufficient, skipping turning off the cooling device in the subspace; or if the energy supply is not sufficient, turning off a cooling device, till it is determined that the energy supply is sufficient, thus minimizing impact of turning off the cooling system on stability.