Abstract: Methods and compositions containing a phorbol ester or a derivative of a phorbol ester are provided for the treatment and prevention of stroke and the sequelae of stroke. Additional compositions and methods are provided which employ a phorbol ester or derivative compound in combination with at least one additional agent to yield more effective treatment tools to treat or prevent stroke and the long term effects of stroke in mammalian subjects.

Abstract: Optionally substituted 4,5,7,8-tetrahydro-(optionally 4-oxo, 4-thioxo or 4-imino)-2H-imidazo[1,2-a]pyrrolo[3,4-e]pyrimidine or 4,5,7,8,9-pentahydro-(optionally 4-oxo, 4-thioxo or 4-imino)-2H-pyrimido[1,2-a]pyrrolo[3,4-e]pyrimidine compounds or Compounds of Formula (I), processes for their production, their use as pharmaceuticals and pharmaceutical compositions comprising the same.

Abstract: Systems and devices configured to reduce thermal design clearances (e.g., between stationary nozzles connected to the inner casing and rotor buckets connected to the rotor) in turbines by actively controlling casing movements and/or locations during turbine operation are disclosed. In one embodiment, a clearance management system includes: a first inner casing support arm shaped to connect to an inner casing of a turbine and extend through an outer casing of the turbine; a seal system disposed about the first inner casing support arm and configured to connect to the outer casing; and a set of actuators disposed on a turbine foundation of the turbine and connected to the first inner casing support arm, the set of actuators located external to the outer casing and configured to adjust a position of the inner casing relative to the outer casing via manipulation of the first inner casing support arm.

Abstract: Methods and compositions containing a phorbol ester or a derivative of a phorbol ester are provided for the treatment of chronic and acute conditions. Such conditions may be caused by disease, be symptoms or sequelae of disease. Chronic and acute conditions may be due to viral infections such as HIV and AIDS, neoplastic diseases stroke, kidney disease, urinary incontinence, autoimmune disorders, Parkinson's disease, prostate hypertrophy, aging, or the treatment of such diseases. Additional compositions and methods are provided which employ a phorbol ester or derivative compound in combination with at least one additional agent to yield more effective treatment tools against acute and chronic conditions in mammalian subjects.

Abstract: The present invention directs to a centrifugal filtration device, for separating living cells, including a spindle (28), a rotary arm (211) which is connected vertically to the spindle (28) and rotates as the spindle rotates, and a microporous membrane filter (31) which is mounted on the rotary arm (211). The microporous membrane filter (31) includes an inlet (311), an outlet (312), a front cavity (313) having the inlet (311) formed thereon, a rear cavity (314) having the outlet (312) formed thereon, and a filter membrane (315) arranged between the front cavity and the rear cavity; the diameter of each filter pore formed in the filter membrane is smaller than that of the cell which needs to be separated. The present invention also discloses a cell separation system.

Abstract: A computer system includes at least one processor and at least one memory operably coupled to the at least one processor. The memory includes a memory pool and a database partitioned into multiple fragments. Each of the fragments is allocated a block of memory from the memory pool and the fragments store compressed data in a columnar table format. A database operation is applied in a compressed format to the compressed data in at least one of the fragments.

Abstract: In a method for beamforming in a multiple input multiple output (MIMO) communication system, a data unit is received from a communication device via a MIMO communication channel, and it is determined whether the data unit satisfies one or more selection criteria. Further, when it is determined that the data unit satisfies the one or more selection criteria, the data unit is selected to be used in developing a steering matrix for transmitting data units to the communication device.

Abstract: A tractor assembly includes a connection unit which is connected between the tractor and the wheel chair. The connection unit includes a fixing member, a top link unit, a bottom link unit and a swing rod so as to form a four-link mechanism. The connection unit includes an engaging unit with an engaging section, and a position unit. The top link unit has a reception hole and the positioning unit has a push rod. When the push rod is located at the first position, the reception hole is closed. When the push rod is located at the second position, the push rod is retracted and the reception hole is exposed. The bottom link unit is pivoted about one end of the swing rod to move the other end of the swing rod to the position of the reception hole, the engaging section is inserted into the reception hole.

Abstract: Chimeric peptides or fusion proteins are disclosed that include a RhoGAP activity domain and at least one specificity domain that targets a specific Rho protein. The fusion proteins can be used to inhibit any GTPase activity within a cell. The fusion proteins are particularly advantageous for the treatment of cancer. The present invention generally relates to chimeric peptides capable of regulating GTPases, and more particularly, to methods of targeting individual GTPases by using GTPase-activating proteins. Such proteins may be used for the treatment of cancers and other GTPase-related diseases. This invention relates to nucleic acid molecules and the encoded GTPase activating proteins, and variants thereof, and to the use of these molecules in the characterization, diagnosis, prevention, and treatment of cell signaling, immune, and cell proliferative disorders, particularly cancer. Disclosed herein are compounds and methods for regulating transcription of a selected gene.

Abstract: Disclosed herein are thermally conductive blended polycarbonate compositions with improved thermal conductivity and mechanical performance properties. The resulting compositions, comprising one or more polycarbonate polymers and one or more thermally conductive fillers, can be used in the manufacture of articles requiring thermally conductive materials with improved mechanical properties such as electronic devices. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

Abstract: The present invention relates to a method and device for monitoring APU turbine vane fracture and rotor shaft jam. The method for monitoring APU turbine vane fracture and rotor shaft jam comprises: acquiring APU messages at multiple time points within a period; obtaining the operation parameters of the APU according to the APU messages, the operation parameters including at least the start time STA; calculating the average value AVG and the deviation index ? of the start time STA within the period; and determining the circumstance of the turbine vane fracture and rotation shaft jam of APU is in stable phase, decline phase or malfunction phase according to the deviation index ?.

Abstract: Embodiments of the present invention provide a method, a device and a communications system for network convergence, which can support a charging manner of a network to which an access user belongs. The method for network convergence includes: after authentication of an access user is successful, receiving, by a second gateway, a PDN connection establishment message corresponding to the access user, where the message carries an access user identifier and is sent by a first gateway, the first gateway is a gateway of a first network in which the access user is currently located, and a service borne by the PDN connection corresponding to the access user includes a network side service of the access user in the first network; and initiating, by the second gateway, according to the access user identifier, a charging procedure corresponding to the access user.

Abstract: The present invention relates to a method for detecting addition of engine lubricant, comprising: determining whether the difference value between the lubricant quantity at a first timing and that at a second timing is greater than a first threshold value; delaying a period and determining whether the difference value between the lubricant quantity at a third timing and that at a fourth timing is greater than a second threshold value in response to that the difference value between the lubricant quantity at the first timing and that at the second timing is greater than the first threshold value; and detecting the lubricant increment in response to that the difference value between the lubricant quantity at the third timing and that at the fourth timing is greater than the second threshold value.

Abstract: The present invention discloses a method for uplink multi-user cooperation communication, including a first, and a second source node and a target node. When transmitting a signal to the target node, the first source node also transmits the signal to the second source node, the second source node changing to a relay node of the first source node and forwarding the signal to the target node; the target node obtains its reception Signal Noise Ratio (SNR) by using a maximal ratio combining mode according to the signal directly transmitted from the first source node and the signal forwarded from the second source node, sets a precoding policy according to the reception SNR, and selects the optimal precoding as a precoding vector which is used when the first source node transmits a signal to the target node.

Abstract: A multi-mode wireless transceiver and a multi-mode switching method thereof are disclosed to provide at least one wireless transceiving interface capable of dynamically switching between multiple frequency bands. The wireless transceiver comprises: a first RF transceiving circuit for transceiving RF signals of a first frequency band; a second RF transceiving circuit for transceiving RF signals of a second frequency band; a first frequency synthesizer and a second frequency synthesizer for generating a first carrier of the first frequency band and a second carrier of the second frequency band respectively; and a switching circuit for outputting the first carrier to the first RF transceiving circuit, and for determining to output one of the first and second carriers to the second RF transceiving circuit according to a control signal.

Abstract: A coordinate measuring machine has 1) an anchor beam with a top end and a bottom end, 2) at least one support beam having a top end and a bottom end, and 3) a cross-beam supported on the top ends of both the anchor beam and the at least one support beam. In addition, the coordinate measuring machine also has 4) a base supporting the bottom ends of the anchor beam and the at least one support beam. At least one of the at least one support beams has a first spring and a second spring. In preferred embodiments, the first spring is adapted to allow movement and is spaced from the second spring in a direction that is generally parallel with the longitudinal axis of the cross-beam.

Abstract: A child safety seat includes a seat base and a safety-belt clamping device disposed on the seat base, and is disposed to a car seat by a safety belt. The safety-belt clamping device includes a bottom seat, a rotatable clamping arm connected pivotally to an end of the bottom seat, and a retainer mounted to an opposite end of the bottom seat and retaining releasably a free end of the rotatable clamping arm thereon. The seat base has a mounting groove. The bottom seat is disposed fixedly on the seat base. The rotatable clamping arm and the retainer are disposed within the mounting groove. When the rotatable clamping arm is retained on the retainer, the safety belt is clamped between the rotatable clamping arm and two sidewalls defining the mounting groove.

Abstract: Technologies are described herein for implementing a universal modulation coding mechanism for a data channel. A user data sequence comprising a first number of bits is received. The user data sequence is encoded into a codeword sequence comprising a second number of bits utilizing a modulation encoder. The modulation encoder may encode the user data sequence based on a set of Markov state transition probabilities. The modulation encoder may implement a data de-compressor algorithm from a lossless data compression scheme. The codeword sequence is output to the data channel. The codeword sequence is subsequently received from the data channel, and the user data sequence is decoded from the codeword sequence utilizing a modulation decoder. The modulation decoder may decode the user data sequence based on the same set of Markov states transition probabilities. The modulation de-coder may implement the data compressor algorithm from the lossless data compression scheme.

Abstract: An impeller of an advection-type fan includes a metal base plate, a shaft and a plurality of plastic blades. The metal base plate includes a shaft-coupling portion and a peripheral portion, with a first plane facing in a first direction and a second plane facing in a second direction opposite to the first direction arranged between the shaft-coupling portion and the peripheral portion. The metal base plate is in a plane form between the shaft-coupling portion and the peripheral portion. The shaft has a fixing end and a free end. The fixing end is coupled with the shaft-coupling portion, and the free end extends in the first direction. Each plastic blade has a coupling portion and an air-driving portion. The coupling portion is coupled with the peripheral portion, and the air-driving portion extends in the second direction.

Abstract: A circuit includes a full-bridge converter circuit coupled to a transformer for converting a first voltage level to a second voltage level. A sensing circuit is coupled to the transformer for sensing a size of a load coupled to the transformer. A digital feedback circuit is coupled to the full-bridge converter and to the sensing circuit for adjusting a rate at which the full-bridge converter is switched based on a signal received from the sensing circuit.