Abstract: Scheduling System Information (SI) in a radio communication system is disclosed. System Frame Number (SFN) and position of System Information is determined in accordance with the SFN. The SI-x is established, and all SIs on the radio frames are distributed discretely at different times for sending. An SI scheduling system and a UE are also disclosed. The technical solution under the present invention optimizes scheduling of SI, avoids excessive network load caused by sequentially sending of all SIs on different sub-frames, and improves the efficiency of scheduling user data.

Abstract: The present invention relates to N-(hetero)aryl-pyrrolidine derivatives of Formula I: which are JAK inhibitors, such as selective JAK1 inhibitors, useful in the treatment of JAK-associated diseases including, for example, inflammatory and autoimmune disorders, as well as cancer.

Abstract: A method for high throughput discovery of proteins fluorescently labeled at a cysteine residue and that undergo a change in fluorescence ratio at 2 wavelengths upon binding an unbound analyte is described. Probes are disclosed which are labeled at a cysteine residue and also probes labeled at both cysteine and lysine with two different fluorophores. These probes are useful for characterization and measurement of hydrophobic species in a fluid sample, particularly characterization and measurement of levels of unbound free fatty acids. A profile of unbound free fatty acids can be determined for an individual which can be used to determine the individual's relative risk for disease.

Abstract: Fibers are spun from a supported array of nanotubes. Fibers are spun using a spinning shaft with, for example, a hook shaped end that contacts the supported nanotubes and twists some of them around each other to begin the fiber. As the twisted nanotubes detach from the support, the shaft moves away from and along the supported array in a controlled direction and at a controlled speed as it spins to twist and detach additional nanotubes from the support and extend the length of the fiber. If the array is pretreated with a dilute polymer solution, excess solution is squeezed out of the growing fiber during spinning, and the polymer may be cured at elevated temperature to provide a strong nanotube composite fiber.

Abstract: Aspects of the invention pertain to enhanced zooming capability of user devices. A user device such as a mobile phone with a camera may capture images of different objects of interest. The capture and zooming limitations of the user device are overcome by replacing, supplementing or otherwise enhancing the image taken with one or more geo-coded images stored in a database. For instance, if the user attempts to zoom in on a feature of an object of interest and exceeds the zooming capability of the user device, a request is sent to a remote server to provide an image showing the feature of the object of interest at a desired resolution. The server determines which, if any, stored images correlate to the captured image of the object of interest. The resulting imagery is provided to the user device and is presented on a display.

Abstract: An electronic device includes a body, a cover, a sliding apparatus, and a latch assembly. The body defines two sliding slots. The sliding apparatus is received in the slots and is slidable relative thereto. The cover is foldable on the body and is rotatably coupled to the sliding apparatus. The latch assembly is fixed to the sliding apparatus. When the latch assembly clasps the body, the sliding apparatus is unlatched from the electronic device, and the cover is slidable relative to the body and is unfolded while the cover slides away from the body.

Abstract: This invention provides novel compounds that are modulators of gamma secretase. The compounds have the formula (I) wherein R2 is a fused bicyclic ring of the formula (II). Also disclosed are methods of modulating gamma secretase activity and methods of treating Alzheimer's disease using the compounds of formula (I).

Abstract: In its many embodiments, the present invention provides a novel class of 5-membered, nitrogen-containing heterocyclic compounds as modulators of gamma secretase, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with the central nervous system using such compounds or pharmaceutical compositions.

Abstract: The present invention provides immunostimulatory combinations of TLR ligands and therapeutic and/or prophylactic methods that include administering an immunostimulatory combination to a subject. In general, the immunostimulatory combinations described herein can provide an increased immune response compared to other immunostimulatory combinations and/or compositions.

Abstract: The present invention relates to nanostructured materials (including nanowires) for use in batteries. Exemplary materials include carbon-comprising, Si-based nanostructures, nanostructured materials disposed on carbon-based substrates, and nanostructures comprising nanoscale scaffolds. The present invention also provides methods of preparing battery electrodes, and batteries, using the nanostructured materials.

Abstract: The present invention provides compounds useful, for example, for treating metabolic disorders in a subject. Such compounds have the general formula I or the general formula III: where the definitions of the variables are provided herein. The present invention also provides compositions that include, and methods for using, the compounds in preparing medicaments and for treating metabolic disorders such as, for example, type II diabetes.

Abstract: Embodiments of this invention disclose a service processing method, a communication system and related device, for making it easier for a user to set up and manage ring personal group, and capable of enhancing system safety. The method comprises: acquiring, by a management client, a ring personal group processing request of a user; and transmitting, by the management client, the ring personal group processing request to a service server over a mobile network, so that the by service server performs the corresponding processing according to the ring personal group processing request. Embodiments of this invention further provide a communication system and related device. Embodiments of this invention make it convenient for the user to set up and manage ring personal group, and make it possible to reduce unnecessary network traffic and enhance system safety.

Abstract: Provided herein are systems and methods for storage, retrieval and sampling of materials.

Abstract: This invention provides variant sequences to miR398 targets in copper/zinc superoxide dismutase (CSD) genes resulting in resistance to down regulation of the CSD by the miR398.

Abstract: The present invention relates to chemokine receptor binding compounds, pharmaceutical compositions and their use. More specifically, the present invention relates to modulators of chemokine receptor activity, preferably modulators of CCR5. These compounds demonstrate protective effects against infection of target cells by a human immunodeficiency virus (HIV).

Abstract: Novel benzamide compounds including their pharmaceutically acceptable isomers, salts, hydrates, solvates and prodrug derivatives having activity against mammalian factor Xa are described. Compositions containing such compounds are also described. The compounds and compositions are useful in vitro or in vivo for preventing or treating coagulation disorders.

Abstract: A data visualization and analysis system (“DVAS”) is described, which provides techniques and data models for modeling, storing, retrieving, analyzing, and visually representing large data sets in a rapid, lightweight, flexible, and highly interactive fashion. A data model and various techniques are described with reference to trace data sets, which are files or other data storage constructs used to record information regarding certain defined events occurring during operation of a computing system or a portion thereof. The DVAS receives and parses one or more trace data sets to create a data model that includes a number of layers and other inner or auxiliary data structures. Based on the data model, the DVAS visually renders one or more sets of geometric objects in accordance with different drawing modes. The drawing modes, which are dynamic and interactive, enable users to effectively visually identify patterns within the trace data sets.

Abstract: NS4B is one of the non-structural proteins of classical swine fever virus. By using functional genetics, we have discovered, in the predicted amino acid sequence of NS4B of CSFV strain Brescia, a motif that resembles those found in the toll-like receptor (TLR) proteins, a group of host cell proteins involved in the development of anti-viral mechanisms. We have located the TLR motif in two groups of amino acid triplets at amino acid positions 2531-3 (residues IYK) and 2566-8 (residues VGI) of the CSFV NS4B glycoprotein. We have constructed a recombinant CSFV (derived from an infectious clone containing the genetic information of the highly virulent strain Brescia) containing amino acid substitutions in the three amino acid residues at positions 2566, 2567 and 2568, where the VGI triplet has been replaced by an AAA triplet inside the NS4B glycoprotein. The obtained virus, named NS4B-VGIv, was completely attenuated in swine, showing a limited ability in spreading during the infection in vivo.

Abstract: The present invention relates to mutant ?8 desaturase genes, which have the ability to convert eicosadienoic acid [20:2 ?-6, EDA] to dihomo-?-linolenic acid [20:3, DGLA] and/or eicosatrienoic acid [20:3 ?-3, ETrA] to eicosatetraenoic acid [20:3 ?-3, ETA]. Isolated nucleic acid fragments and recombinant constructs comprising such fragments encoding ?8 desaturase along with methods of making long-chain polyunsaturated fatty acids (PUFAs) using these mutant ?8 desaturases in plants and oleaginous yeast are disclosed.

Abstract: Compositions, pharmaceutical preparations and methods are disclosed for protecting non-neoplastic cells from damage caused by cancer chemotherapeutic agents or radiation therapy, during the course of cancer therapy or bone marrow transplant. These are based on the use of chemoprotective inducing agents that induce or increase production of cellular detoxification enzymes in target cell populations. The compositions and methods are useful to reduce or prevent hair loss, gastrointestinal distress and lesions of the skin and oral mucosa that commonly occur in patients undergoing cancer therapy. Also disclosed is a novel assay system for identifying new chemoprotective inducing agents.