Abstract: The present disclosure provides a method for evaluating a geological storage amount of carbon dioxide (CO2) in a fractured-vuggy carbonate reservoir, including: performing image identification on a three-dimensional scanned image of a rock sample to obtain identified rock information; inputting the identified rock information to a computational fluid dynamics-based numerical simulator for constructing a fractured-vuggy rock structure model, and obtaining geometric topological information of the rock sample based on the fractured-vuggy rock structure model; inputting relevant parameters of the rock sample and the geometric topological information to a multi-scale multi-phase flow numerical model for numerical simulation of multi-phase flow migration of CO2 in models of different scales and obtaining a multi-scale numerical simulation result; and calculating a multi-scale CO2 storage efficiency based on the multi-scale numerical simulation result.

Abstract: Provided are certain BCL-2 inhibitors, pharmaceutical compositions thereof, and methods of use thereof.

Abstract: A first terminal obtains a first transmission resource that is sent by an access network device and that is used by the first terminal to send data on a sidelink, where the sidelink is a wireless communication link between the first terminal and a second terminal, and the first transmission resource is a resource of an unlicensed spectrum. The first terminal performs a channel access procedure on the unlicensed spectrum. The first terminal sends first information to the access network device when the first terminal determines that a failure occurs in the channel access procedure performed on the unlicensed spectrum, where the first information is used to request to allocate a second transmission resource to the sidelink of the unlicensed spectrum.

Abstract: An electronic device including circuitry configured to send a request to a core network, wherein the request informs the core network that the electronic device is capable of aggregating data and relaying data from other electronic devices; receive one or more aggregation policies from the core network, wherein the one or more aggregation policies provide parameters that instruct how the electronic device is to aggregate and relay data; receive data from the other electronic devices; aggregate the data from the other electronic devices based on the parameters; and send the aggregated data to the core network.

Abstract: A method of categorizing text entries on a document can include determining, for each of a plurality of text bounding boxes in the document, respective text, respective coordinates, and respective input embeddings. The method may further include defining a graph of the plurality of bounding boxes, the graph comprising a plurality of connections among the plurality of bounding boxes, each connection comprising a first and second bounding box and zero or more respective intermediate bounding boxes. The method may further include determining a respective attention value for each connection according to a quantity of intermediate bounding boxes in the connection and, based on a the respective attention values and a transformer-based machine learning model applied to the respective input embeddings and respective coordinates, determining output embeddings for each bounding box and, based on the respective output embeddings, generating a bounding box label for each bounding box.

Abstract: A chip cooler with high pressure bearing capacity installed on a chip it cools. The chip cooler has a cooler body having a refrigerant channel formed corresponding to the internal construction of the cooler body and configured to guide the flow of a refrigerant, and two liquid inlet and outlet channels formed corresponding to the construction at an edge of the cooler body, connected to the refrigerant channel and configured to transversely communicate the inside and outside of the cooler body; and a reinforced connecting piece is disposed in at least one of the two liquid inlet and outlet channels, the reinforced connecting piece at least connects opposite upper and lower wall surfaces of the liquid inlet and outlet channel, and a flow gap exists between the reinforced connecting piece and the liquid inlet and outlet channel.

Abstract: Provided is a stress blank angle eliminating device and method for a dynamic true triaxial electromagnetic Hopkinson bar. Objectives of eliminating influence of a stress blank angle in a sample in a test and preventing permanent deformation caused by mutual collision between the Hopkinson bars are achieved. The adjustable test device for eliminating the stress blank angle eliminates influence of the stress blank angle generated by the sample in a triaxial six-direction dynamic impact test process, and is convenient for obtaining real dynamic failure parameters of the sample.

Abstract: A bispecific antibody simultaneously targeting two different epitopes or targets is coupled with a camptothecin drug to form a bispecific antibody-toxin conjugate that is stable in treatment and excellent in uniformity, and a drug-to-antibody ratio (DAR) thereof is 6.0-8.0. The antibody-toxin conjugate has a structure as represented by general formula (I), wherein Ab represents the bispecific antibody simultaneously targeting two different epitopes or targets, which is coupled with a linker-camptothecin drug. In addition, the present invention further relates to a preparation and purification method for the antibody-toxin conjugate, and an application thereof in tumor treatment. Furthermore, the present invention further relates to a linker-drug compound capable of being coupled with Ab to form the antibody-toxin conjugate.

Abstract: The present disclosure provides antibody drug conjugates comprising antibodies and antigen-binding fragments thereof that bind to human CEA and a linker-payload, a pharmaceutical composition comprising the anti-CEA antibody drug conjugate, and use of the anti-CEA antibody drug conjugate for treating a CEA-related diseases or disorders.

Abstract: Embodiments of the present disclosure relate to a method, a device and a computer readable media for use with robot. The robot has at least one arm. The method includes receiving a force applied onto a force sensor attached at an end of the arm; determining a first vector from the force sensor; determining a second vector based on a torque of a joint of the robot, the joint being coupled to the arm; and determining a transformation relation between the first vector and the second vector.

Abstract: The present disclosure relates to methods and devices for memory erase. In one example, a method for operating a memory device includes increasing a voltage of a source line (SL) coupled to a memory string from an initial voltage at a beginning of a time period, where the voltage of the SL is increased to an erase voltage at an end of the time period. The memory device can apply a first voltage to a first word line (WL) before the end of the time period. The memory device can apply a second voltage to a second WL adjacent to the first WL before the end of the time period. The memory device can further apply a third voltage to the second WL no later than the end of the time period, where the third voltage is higher than the second voltage.

Abstract: A control system provides automated control of gas washout of a patient interface, such as a mask or nasal prongs. A gas washout vent assembly of the system may include a variable exhaust area such as one defined by overlapping apertures of the assembly or a conduit having a variable gas passage channel. The vent assembly may be formed by nested structures, such as conic or cylindrical members, each having an opening of the overlapping apertures. The vent assembly may be attached substantially near or included with the patient interface. An actuator of the assembly, such as a solenoid or voice coil, manipulates an aperture of the vent assembly. The actuator may be configured for control by a controller to change the exhaust area of the vent assembly based on various methodologies including, for example, sleep detection, disordered breathing event detection, rebreathing volume calculation and/or leak detection.

Abstract: Disclosed is a non-natural amatoxin-type antibody conjugate, said conjugate similar to the natural amatoxin is linked to a biopharmaceutically acceptable salt with a target biomolecule so as to obtain stability in blood plasma, and efficiently kill tumor cells in cells.