Patents by Inventor Ana Belén García García

Ana Belén García García has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • IMIDAZO[1,2-B]PYRIDAZINE BASED TRICYCLIC COMPOUNDS AS INHIBITORS OF HASPIN AND THERAPEUTIC USES THEREOF
    Publication number: 20240199630
    Abstract: The present invention relates to a group of compounds with a tricyclic core based on imidazo[1,2-b]pyridazine of formula (I): which are inhibitors of HASPIN, whose activity is required for the proliferation of certain tumoral cells, so the compounds of the invention are useful for the prevention and/or treatment of cancer, alone or in combination with chemotherapeutic agents.
    Type: Application
    Filed: March 23, 2022
    Publication date: June 20, 2024
    Inventors: Joaquín PASTOR FERNÁNDEZ, Sonia MARTÍNEZ GONZÁLEZ, Carmen BLANCO APARICIO, Ana Belén GARCÍA GARCÍA, Sonsoles RODRÍGUEZ ARÍSTEGUI, Cristina Ana GÓMEZ DE LA OLIVA, María Isabel ALBARRÁN SANTIÑO, Antonio CEBRIÁ GÓMEZ, Marcos MALUMBRES MARTÍNEZ
  • Macrocyclic compounds as protein kinase inhibitors
    Patent number: 9808466
    Abstract: There is provided compounds of formula I, wherein R1, R2a, R2b, R2c, X, Y, Z, R3 and ring A/B have meanings given in the description, and pharmaceutically-acceptable esters, amides, solvates or salts thereof, which compounds are useful in the treatment of diseases in which inhibition of a protein or lipid kinase (e.g. PI3-K, particularly class I PI3K, PIM family kinase and/or mTOR) is desired and/or required, and particularly in the treatment of cancer. The invention also relates to combinations containing such compounds.
    Type: Grant
    Filed: January 26, 2016
    Date of Patent: November 7, 2017
    Inventors: Joaquín Pastor Fernández, Rosa María Álvarez Escobar, Rosario Concepción Riesco Fagundo, Ana Belén García García, Antonio Rodríguez Hergueta, Jose Ignacio Martín Hernando, Carmen Blanco Aparicio, David Álvaro Cebrián Muñoz
  • MACROCYCLIC COMPOUNDS AS PROTEIN KINASE INHIBITORS
    Publication number: 20160296528
    Abstract: There is provided compounds of formula I, wherein R1, R2a, R2b, R2c, X, Y, Z, R3 and ring A/B have meanings given in the description, and pharmaceutically-acceptable esters, amides, solvates or salts thereof, which compounds are useful in the treatment of diseases in which inhibition of a protein or lipid kinase (e.g. PI3-K, particularly class I PI3K, PIM family kinase and/or mTOR) is desired and/or required, and particularly in the treatment of cancer. The invention also relates to combinations containing such compounds.
    Type: Application
    Filed: January 26, 2016
    Publication date: October 13, 2016
    Inventors: Joaquin Pastor Fernández, Rosa María Álvarez Escobar, Rosario Concepción Riesco Fagundo, Ana Belén García García, Antonio Rodríguez Hergueta, Jose Ignacio Martín Hernando, Carmen Blanco Aparicio, David Álvaro Cebrián Muñoz
  • Macrocyclic compounds as protein kinase inhibitors
    Patent number: 9284334
    Abstract: There is provided compounds of formula I, wherein R1, R2a, R2b, R2c, X, Y, Z, R3 and ring A/B have meanings given in the description, and pharmaceutically-acceptable esters, amides, solvates or salts thereof, which compounds are useful in the treatment of diseases in which inhibition of a protein or lipid kinase (e.g. PI3-K, particularly class I PI3K, PIM family kinase and/or mTOR) is desired and/or required, and particularly in the treatment of cancer. The invention also relates to combinations containing such compounds.
    Type: Grant
    Filed: May 18, 2012
    Date of Patent: March 15, 2016
    Assignee: Fundación Centro Nacional de Investigaciones Oncologicas Carlos III
    Inventors: Joaquin Pastor Fernández, Rosa Maria Álvarez Escobar, Rosario Concepción Riesco Fagundo, Ana Belén García García, Antonio Rodriguez Hergueta, Jose Ignacio Martín Hernando, Carmen Blanco Aparicío, David Álvaro Cebrián Muñoz
  • MACROCYCLIC COMPOUNDS AS PROTEIN KINASE INHIBITORS
    Publication number: 20140256717
    Abstract: There is provided compounds of formula I, wherein R1, R2a, R2b, R2c, X, Y, Z, R3 and ring A/B have meanings given in the description, and pharmaceutically-acceptable esters, amides, solvates or salts thereof, which compounds are useful in the treatment of diseases in which inhibition of a protein or lipid kinase (e.g. PI3-K, particularly class I PI3K, PIM family kinase and/or mTOR) is desired and/or required, and particularly in the treatment of cancer. The invention also relates to combinations containing such compounds.
    Type: Application
    Filed: May 18, 2012
    Publication date: September 11, 2014
    Applicant: Centro Nacional de Investigaciones Oncológicas (CNIO)
    Inventors: Joaquín Pastor Fernández, Rosa Maria Álvarez Escobar, Rosario Concepción Riesco Fagundo, Ana Belén García García, Antonio Rodríguez Hergueta, Jose Ignacio Martin Hernando, Carmen Blanco Aparicio, David Álvaro Cebrián Muñoz
  • Imidazolothiadiazoles for use as protein kinase inhibitors
    Patent number: 8563550
    Abstract: There is provided compounds of formula (I), wherein Z, M, R1, X, R2, R3 and B have meanings given in the description, and pharmaceutically-acceptable esters, amides, solvates or salts thereof, which compounds are useful in the treatment of diseases in which inhibition of a protein kinase (e.g. a PIM family kinase or PI3-K) is desired and/or required, and particularly in the treatment of cancer.
    Type: Grant
    Filed: September 29, 2008
    Date of Patent: October 22, 2013
    Inventors: Paolo Pevarello, Ana Maria Garcia Collazo, Ana Belen Garcia Garcia
  • Imidazolothiadiazoles for Use as Protein Kinase Inhibitors
    Publication number: 20110190289
    Abstract: There is provided compounds of formula (I), wherein Z, M, R1, X, R2, R3 and B have meanings given in the description, and pharmaceutically-acceptable esters, amides, solvates or salts thereof, which compounds are useful in the treatment of diseases in which inhibition of a protein kinase (e.g. a PIM family kinase or PI3-K) is desired and/or required, and particularly in the treatment of cancer.
    Type: Application
    Filed: September 29, 2008
    Publication date: August 4, 2011
    Applicant: Centro Nacional De Investigaciones Oncologicas (CNIO)
    Inventors: Paolo Pevarello, Ana Maria Garcia Collazo, Ana Belen Garcia Garcia