Patents by Inventor Ana Cristina Calvo Royo

Ana Cristina Calvo Royo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS OF INCREASING MUSCLE MASS USING NON-TOXIC TETANUS TOXIN C FRAGMENT (TTC)
    Publication number: 20170151316
    Abstract: The present disclosure relates to the use of the non-toxic proteolytic C fragment of tetanus toxin and plasmids encoding such protein fragment to increase muscle mass and/or muscle strength in a subject in need thereof. As such, methods of ameliorating the severity of a pathological condition characterized, at least in part, by a decreased amount, development, or metabolic activity of muscle are provided. The disclosed compositions and method are also useful for the treatment of condition in which increase in muscle mass and muscle strength are desirable, including cosmetic uses.
    Type: Application
    Filed: July 1, 2015
    Publication date: June 1, 2017
    Applicant: SPHERIUM BIOMED, S.L.
    Inventors: Jordi ORTIZ SAGRISTA, Ramon BOSSER ARTAL, Laura MORENO MARTINEZ, Ana Cristina CALVO ROYO, Maria Jesus MUÑOZ GONZALVO, Pilar ZARAGOZA FERNANDEZ, Rosario OSTA PINZOLAS
  • Therapeutic Use of the Encoding Sequence of the Carboxy-Terminal Domain of the Heavy Chain of the Tetanus Toxin
    Publication number: 20160017008
    Abstract: The present invention relates to the therapeutic use of the encoding sequence of the carboxy-terminal domain of the heavy chain of the tetanus toxin and of the polypeptide encoded by said sequence, preferably for the treatment of amyotrophic lateral sclerosis (ALS).
    Type: Application
    Filed: December 15, 2014
    Publication date: January 21, 2016
    Inventors: MARIA MORENO IGOA, ANA CRISTINA CALVO ROYO, MARIA JESÚS MUÑOZ GONZALVO, MARIA PILAR ZARAGOZA FERNÁNDEZ, ROSARIO OSTA PINZOLAS, JOSÉ AGUILERA AVILA
  • Therapeutic use of the encoding sequence of the carboxy-terminal domain of the heavy chain of the tetanus toxin
    Patent number: 8945586
    Abstract: The present invention relates to the therapeutic use of the carboxy-terminal domain of the heavy chain of the tetanus toxin for the treatment of amyotrophic lateral sclerosis (ALS).
    Type: Grant
    Filed: April 5, 2010
    Date of Patent: February 3, 2015
    Assignees: University of Zaragoza, Autonomous University of Barcelona
    Inventors: María Moreno Igoa, Ana Cristina Calvo Royo, Maria Jesús Muñoz Gonzalvo, Maria Pilar Zaragoza Fernández, Rosario Osta Pinzolas, José Aguilera Avila
  • METHOD FOR THE DIAGNOSIS, PROGNOSIS AND MONITORING OF MUSCULAR DEGENERATION
    Publication number: 20130316933
    Abstract: The invention relates to methods based on the quantification of a set of biomarkers, preferably in biological samples isolated from skeletal muscle, for performing the diagnosis, prognosis and/or monitoring of muscular degeneration, preferably muscular degeneration caused by motor neuron diseases, more preferably amyotrophic lateral sclerosis (ALS); and to a kit for the diagnosis, prognosis and monitoring of said type of diseases. The method in the invention for the prognosis and/or monitoring of muscular degeneration makes it possible to determine the rate of progression of said degeneration (fast or slow rate of progression in relation to the normal rate of progression).
    Type: Application
    Filed: December 7, 2011
    Publication date: November 28, 2013
    Applicant: Universidad de Zaragoza
    Inventors: Rosario Osta Pinzolas, Maria Jesus Munoz Gonzalvo, Pilar Zaragoza Fernandez, Ana Cristina Calvo Royo, Raquel Manzano Martinez, Alberto Garcia Redondo, Paz Torre Merino
  • Therapeutic Use of the Encoding Sequence of the Carboxy-Terminal Domain of the Heavy Chain of the Tetanus Toxin
    Publication number: 20100261656
    Abstract: The present invention relates to the therapeutic use of the encoding sequence of the carboxy-terminal domain of the heavy chain of the tetanus toxin and of the polypeptide encoded by said sequence, preferably for the treatment of amyotrophic lateral sclerosis (ALS).
    Type: Application
    Filed: April 5, 2010
    Publication date: October 14, 2010
    Applicants: UNIVERSITY OF ZARAGOZA, AUTONOMOUS UNIVERSITY OF BARCELONA
    Inventors: Maria Moreno Igoa, Ana Cristina Calvo Royo, Maria Jesús Muñoz Gonzalvo, Maria Pilar Zaragoza Fernández, Rosario Osta Pinzolas, José Aguilera Avila