Abstract: A defoamed aqueous composition including 5 to 75 weight-% of at least one anionic polymer, 0.05 to 5 weight-% of at least one water insoluble liquid defoamer and 0.005 to 3 weight-% of at least one polysaccharide, based on 100 weight-% of the composition. The composition gives predictable air content in non-air entrained and air-entrained mortar and concrete.

Abstract: A device (1) for parallel dispensing a print medium (10) onto a substrate, in particular for producing one or more conductor tracks on a semiconductor substrate, having a printing unit (6), which includes a plurality of dispenser nozzles for simultaneous discharge of the print medium (10), and having a drive (5), which is configured to generate a relative movement between the printing unit (6) and the substrate (4) in a movement direction (7). At least first usnd second dispenser nozzles are arranged spaced apart from one another transversely in relation to the movement direction (7). The first dispenser nozzle and a third dispenser nozzle are arranged spaced apart from one another along a common first longitudinal axis at a first nozzle spacing, and the first longitudinal axis runs parallel to the movement direction (7).

Abstract: A hybrid material includes a protein matrix and nanoparticles (NPs) of a type of Cu; a preparation method thereof; and the uses thereof. The hybrid material displays activity that inhibits SARS-CoV-2 proteins, which makes it usable as a biocidal agent and as an agent for coating and disinfecting materials selected from metal, paper, textiles and approved surgical face masks.

Abstract: Methods for the treatment of non-hardened cement compositions, especially returned concrete, and admixtures suitable to be used in such methods. The admixtures include modified starch and a sugar. Also, solid granules obtained by the methods and fresh concrete or mortar utilizing solid granules thus obtained.

Abstract: A defoamed aqueous composition including 5 to 75 weight-% of at least one anionic polymer, 0.05 to 5 weight-% of at least one water insoluble liquid defoamer and 0.005 to 3 weight-% of at least one polysaccharide, based on 100 weight-% of the composition. The composition gives predictable air content in non-air entrained and air-entrained mortar and concrete.

Abstract: The present invention relates to a compound of formula (I) for use as a medicine, in particular for use in the treatment of diseases mediated by the actvation of the protein kinase Erk1/2, such as neurogenerative illnesses like Alzheimer's and related dementia, epilepsy, Parkinson's disease, Huntington's disease, or stroke, and likewise relates to the pharmaceutical compositions containing said compound. The compound of formula (I) effectively inhibits the activation of the enzyme Erk1/2 induced by the tissue plasminogen activator (TPA) and also effectively inhibits the apoptosis generated by the ?-amyloid peptide.

Abstract: The present invention relates to a compound of formula (I) for use as a medicine, in particular for use in the treatment of diseases mediated by the actvation of the protein kinase Erk1/2, such as neurogenerative illnesses like Alzheimer's and related dementia, epilepsy, Parkinson's disease, Huntington's disease, or stroke, and likewise relates to the pharmaceutical compositions containing said compound. The compound of formula (I) effectively inhibits the activation of the enzyme Erk1/2 induced by the tissue plasminogen activator (TPA) and also effectively inhibits the apoptosis generated by the ?-amyloid peptide.

Abstract: Process for purifying 3,4-dihydroxyphenylglycol (DHPG) from any part of the plant, from the products or by-products derived from olive trees or any other vegetable product of the families Oleaceae, Orobanchaceae, Plantaginaceae, Compositae, Lamiaceae, Acanthaceae and/or Scrophulariaceae, and which comprises 1 or more steps wherein the initial product is introduced into at least one ion-exchange resin column, and in potentially subsequent steps the product eluted in the preceding column is introduced into an ion-exchange resin and/or a non-ionic adsorption resin column. Moreover, it relates to the DHPG extract obtainable by means of the process disclosed and to the applications thereof.

Abstract: Sequences and protocols for treatment of eye conditions by use of RNA interference are disclosed. Target genes are selected from those responsible for aqueous flow or aqueous outflow, while particularly preferred conditions to be treated include glaucoma and uveitis.

Abstract: The present invention relates to methods and compositions that decrease intraocular pressure (IOP) of the eye. The compositions of the invention comprise short interfering nucleic acid molecules (siNA) including, but not limited to, siRNA that decrease expression of genes associated with production or drainage of intraocular fluid. The compositions of the invention can be used in the preparation of a medicament for the treatment of an eye conditions displaying increased IOP such as glaucoma, infection, inflammation, uveitis, and diabetic retinopathy. The methods of the invention comprise the administration to a patient in need thereof an effective amount of one or more siNAs of the invention.

Abstract: The present invention relates to a method for obtaining purified hydroxytyrosol from products and by-products derived from the olive tree by means of two-step chromatographic treatment. The invention uses a non-activated ion exchange resin chromatographic method, followed by a second treatment on an XAD-type absorbent non-ionic resin which concentrates and completely purifies the hydroxytyrosol by means of elution with a methanol or ethanol:water dissolution (from 30 to 33%). The method of the invention can also be applied to two-phase pomaces, three-phase pomaces and stones if they are subjected to a steam explosion process.

Abstract: The present invention relates to a method for obtaining purified hydroxytyrosol from products and by-products derived from the olive tree by means of two-step chromatographic treatment. The invention uses a non-activated ion exchange resin chromatographic method, followed by a second treatment on an XAD-type absorbent non-ionic resin which concentrates and completely purifies the hydroxytyrosol by means of elution with a methanol or ethanol:water dissolution (from 30 to 33%). The method of the invention can also be applied to two-phase pomaces, three-phase pomaces and stones if they are subjected to a steam explosion process.