Patents by Inventor Ana Luisa FERREIRA SIMPLICIO

Ana Luisa FERREIRA SIMPLICIO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Brain permeant peptidomimetic beta-secretase 1 inhibitors for the treatment or prophylaxis of neurological disorders or conditions
    Patent number: 9919021
    Abstract: The present application presents novel peptidomimetic substituted hydroxyethylene compounds, which are inhibitors of beta amyloid cleavage enzyme, capable to permeate the brain and to achieve therapeutic concentrations in the target organ, the brain. These compounds are incorporated in pharmaceutical compositions and applied in the treatment or prophylaxis of neurological disorders or conditions and also other disorders or conditions including Down's syndrome and diabetes.
    Type: Grant
    Filed: April 15, 2016
    Date of Patent: March 20, 2018
    Assignee: IBET—INSTITUTO DE BIOLOGIA EXPERIMENTAL E TECNOLÓGICA
    Inventors: Helder Joao Ferreira Vila Real, Ana Luisa Ferreira Simplicio, Olga Iranzo Casanova, Christopher David Maycock
  • BRAIN PERMEANT PEPTIDOMIMETIC BETA-SECRETASE 1 INHIBITORS FOR THE TREATMENT OR PROPHYLAXIS OF NEUROLOGICAL DISORDERS OR CONDITIONS
    Publication number: 20170296618
    Abstract: The present application presents novel peptidomimetic substituted hydroxyethylene compounds, which are inhibitors of beta amyloid cleavage enzyme, capable to permeate the brain and to achieve therapeutic concentrations in the target organ, the brain. These compounds are incorporated in pharmaceutical compositions and applied in the treatment or prophylaxis of neurological disorders or conditions and also other disorders or conditions including Down's syndrome and diabetes.
    Type: Application
    Filed: April 15, 2016
    Publication date: October 19, 2017
    Inventors: Helder Joao FERREIRA VILA REAL, Ana Luisa FERREIRA SIMPLICIO, Olga IRANZO CASANOVA, Christopher David MAYCOCK