Patents by Inventor Ana M. Soto

Ana M. Soto has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Androgen-induced suppressor of cell proliferation and uses thereof
    Patent number: 6994992
    Abstract: The invention provides novel AS3 nucleic acid sequences, AS3 polypeptides, anti-AS3 antibodies, and methods for modulating cell proliferation and detecting compounds that modulate cell proliferation. Diagnostic and therapeutic methods utilizing compositions of the invention are also provided.
    Type: Grant
    Filed: February 24, 2000
    Date of Patent: February 7, 2006
    Assignee: Trustees of Tufts College
    Inventors: Ana M. Soto, Carlos Sonnenschein, Peter Geck, Jozsef Szelei
  • Inhibiting proliferation of cancer cells
    Publication number: 20020123080
    Abstract: A method of testing cancer cells is described. Assays are provided for determining the potential for inhibiting cancer cells proliferation using albumin-derived peptides. The methods of the present invention allow for drug screening as well as for evaluation of biopsied tumors.
    Type: Application
    Filed: August 14, 2001
    Publication date: September 5, 2002
    Applicant: Tufts University
    Inventors: Carlos Sonnenschein, Ana M. Soto
  • Inhibiting proliferation of cancer cells
    Patent number: 6274305
    Abstract: A method of testing cancer cells is described. Assays are provided for determining the potential for inhibiting cancer cells proliferation using albumin-derived peptides. The methods of the present invention allow for drug screening as well as for evaluation of biopsied tumors.
    Type: Grant
    Filed: December 19, 1996
    Date of Patent: August 14, 2001
    Assignee: Tufts University
    Inventors: Carlos Sonnenschein, Ana M. Soto
  • In-vitro methods for identifying compositions which are agonists and antagonists of androgens
    Patent number: 5135849
    Abstract: The present invention provides general protocols by which a substance may be identified and characterized as an androgen agonist and/or an androgen antagonist. The described protocols are in-vitro methods which utilize androgen dependent cells in culture and a medium comprising an inhibitor endogenous to the sera of humans and animals which is able to prevent the proliferation of these cultured cells in-vitro. The methodology is rapid, reproducible, and accurate; and provides the major advantage of being able to test large numbers of unevaluated substances for their androgen agonistic and/or antagonistic properties as primary properties or secondary side-effects.
    Type: Grant
    Filed: April 18, 1989
    Date of Patent: August 4, 1992
    Assignee: Trustees of Tufts College
    Inventors: Ana M. Soto, Carlos Sonnenschein
  • In-vitro methods for identifying compositions which are agonists and antagonists of estrogens
    Patent number: 4859585
    Abstract: The present invention provides two general protocols by which a substance may be identified and characterized as an estrogen agonist and/or an estrogen antagonist. The protocols are in-vitro methods which utilize estrogen dependent cells in culture and a medium comprising an inhibitor endogenous to the sera of adult humans which is able to prevent the proliferation of cultured cells in-vitro. The methodology is rapid, reproducible, accurate and provides the major advantage of being able to screen large numbers of substances for their primary or secondary side effects in a large variety of medical and environmental applications.
    Type: Grant
    Filed: April 17, 1986
    Date of Patent: August 22, 1989
    Assignee: Trustees of Tufts College
    Inventors: Carlos Sonnenschein, Ana M. Soto